node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STM1301 | hisI | STM1301 | STM2078 | Putative mutator MutT protein; Similar to E. coli orf, hypothetical protein (AAC74829.1); Blastp hit to AAC74829.1 (135 aa), 77% identity in aa 1 - 135; Belongs to the Nudix hydrolase family. | phosphoribosyl-AMP cyclohydrolase; Bifunctional; histidine biosynthesis bifunctional protein HISIE [includes:phosphoribosyl-amp cyclohydrolase ]. (SW:HIS2_SALTY); phosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family. | 0.872 |
STM1301 | mazG | STM1301 | STM2954 | Putative mutator MutT protein; Similar to E. coli orf, hypothetical protein (AAC74829.1); Blastp hit to AAC74829.1 (135 aa), 77% identity in aa 1 - 135; Belongs to the Nudix hydrolase family. | Putative pyrophosphatase; Similar to E. coli orf, hypothetical protein (AAC75823.1); Blastp hit to AAC75823.1 (263 aa), 93% identity in aa 2 - 263. | 0.775 |
STM1301 | yeaZ | STM1301 | STM1820 | Putative mutator MutT protein; Similar to E. coli orf, hypothetical protein (AAC74829.1); Blastp hit to AAC74829.1 (135 aa), 77% identity in aa 1 - 135; Belongs to the Nudix hydrolase family. | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | 0.713 |
dnaK | hflB | STM0012 | STM3296 | Chaperone Hsp70; Acts as a chaperone. | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.916 |
dnaK | yeaZ | STM0012 | STM1820 | Chaperone Hsp70; Acts as a chaperone. | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | 0.414 |
hflB | dnaK | STM3296 | STM0012 | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Chaperone Hsp70; Acts as a chaperone. | 0.916 |
hisI | STM1301 | STM2078 | STM1301 | phosphoribosyl-AMP cyclohydrolase; Bifunctional; histidine biosynthesis bifunctional protein HISIE [includes:phosphoribosyl-amp cyclohydrolase ]. (SW:HIS2_SALTY); phosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family. | Putative mutator MutT protein; Similar to E. coli orf, hypothetical protein (AAC74829.1); Blastp hit to AAC74829.1 (135 aa), 77% identity in aa 1 - 135; Belongs to the Nudix hydrolase family. | 0.872 |
hisI | mazG | STM2078 | STM2954 | phosphoribosyl-AMP cyclohydrolase; Bifunctional; histidine biosynthesis bifunctional protein HISIE [includes:phosphoribosyl-amp cyclohydrolase ]. (SW:HIS2_SALTY); phosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family. | Putative pyrophosphatase; Similar to E. coli orf, hypothetical protein (AAC75823.1); Blastp hit to AAC75823.1 (263 aa), 93% identity in aa 2 - 263. | 0.527 |
hisI | yeaZ | STM2078 | STM1820 | phosphoribosyl-AMP cyclohydrolase; Bifunctional; histidine biosynthesis bifunctional protein HISIE [includes:phosphoribosyl-amp cyclohydrolase ]. (SW:HIS2_SALTY); phosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family. | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | 0.604 |
mazG | STM1301 | STM2954 | STM1301 | Putative pyrophosphatase; Similar to E. coli orf, hypothetical protein (AAC75823.1); Blastp hit to AAC75823.1 (263 aa), 93% identity in aa 2 - 263. | Putative mutator MutT protein; Similar to E. coli orf, hypothetical protein (AAC74829.1); Blastp hit to AAC74829.1 (135 aa), 77% identity in aa 1 - 135; Belongs to the Nudix hydrolase family. | 0.775 |
mazG | hisI | STM2954 | STM2078 | Putative pyrophosphatase; Similar to E. coli orf, hypothetical protein (AAC75823.1); Blastp hit to AAC75823.1 (263 aa), 93% identity in aa 2 - 263. | phosphoribosyl-AMP cyclohydrolase; Bifunctional; histidine biosynthesis bifunctional protein HISIE [includes:phosphoribosyl-amp cyclohydrolase ]. (SW:HIS2_SALTY); phosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family. | 0.527 |
yeaZ | STM1301 | STM1820 | STM1301 | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | Putative mutator MutT protein; Similar to E. coli orf, hypothetical protein (AAC74829.1); Blastp hit to AAC74829.1 (135 aa), 77% identity in aa 1 - 135; Belongs to the Nudix hydrolase family. | 0.713 |
yeaZ | dnaK | STM1820 | STM0012 | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | Chaperone Hsp70; Acts as a chaperone. | 0.414 |
yeaZ | hisI | STM1820 | STM2078 | Putative molecular chaperone; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does n [...] | phosphoribosyl-AMP cyclohydrolase; Bifunctional; histidine biosynthesis bifunctional protein HISIE [includes:phosphoribosyl-amp cyclohydrolase ]. (SW:HIS2_SALTY); phosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family. | 0.604 |