node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
iagB | invA | STM2877 | STM2896 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | 0.624 |
iagB | invB | STM2877 | STM2895 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion- competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone SopA, SopE, SopE2 and SipA; Belongs to the SpaK family. | 0.930 |
iagB | invC | STM2877 | STM2894 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Surface presentation of antigens; Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells. | 0.872 |
iagB | invE | STM2877 | STM2897 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Invasion protein; Involved in the triggering of intracellular events that lead to microbial internalization. These events include increase in calcium level, redistribution of actin microfilaments, and changes in the normal structure of the microvilli. Encoded within the type III secretion system (SPI-1 TTSS), it is essential for the translocation of protein effectors into host cells. Forms a complex with SipB and SipC in the presence of their chaperone SicA. Positively regulates the secretion of SPI-1 TTSS effector proteins SipB, SipC and SipD and negatively influences the secretion of [...] | 0.842 |
iagB | invF | STM2877 | STM2899 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Invasion protein; Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.559 |
iagB | invG | STM2877 | STM2898 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Outer membrane invasion protein; Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane. | 0.967 |
iagB | invH | STM2877 | STM2900 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Invasion protein; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Pilot protein that is required for the proper localization of the secretin InvG/SctC in the outer membrane. Required for the secretion of the Sip virulence factors. | 0.718 |
iagB | invI | STM2877 | STM2893 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.978 |
iagB | invJ | STM2877 | STM2892 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | 0.839 |
iagB | orgA | STM2877 | STM2869 | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | Putative flagellar biosynthesis/type III secretory pathway protein; Oxygen-regulated protein required for bacterial internalization. | 0.682 |
invA | iagB | STM2896 | STM2877 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family. | 0.624 |
invA | invB | STM2896 | STM2895 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion- competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone SopA, SopE, SopE2 and SipA; Belongs to the SpaK family. | 0.973 |
invA | invC | STM2896 | STM2894 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Surface presentation of antigens; Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells. | 0.999 |
invA | invE | STM2896 | STM2897 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Invasion protein; Involved in the triggering of intracellular events that lead to microbial internalization. These events include increase in calcium level, redistribution of actin microfilaments, and changes in the normal structure of the microvilli. Encoded within the type III secretion system (SPI-1 TTSS), it is essential for the translocation of protein effectors into host cells. Forms a complex with SipB and SipC in the presence of their chaperone SicA. Positively regulates the secretion of SPI-1 TTSS effector proteins SipB, SipC and SipD and negatively influences the secretion of [...] | 0.998 |
invA | invF | STM2896 | STM2899 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Invasion protein; Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.959 |
invA | invG | STM2896 | STM2898 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Outer membrane invasion protein; Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane. | 0.999 |
invA | invH | STM2896 | STM2900 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Invasion protein; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Pilot protein that is required for the proper localization of the secretin InvG/SctC in the outer membrane. Required for the secretion of the Sip virulence factors. | 0.877 |
invA | invI | STM2896 | STM2893 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.989 |
invA | invJ | STM2896 | STM2892 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | 0.997 |
invA | orgA | STM2896 | STM2869 | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Putative flagellar biosynthesis/type III secretory pathway protein; Oxygen-regulated protein required for bacterial internalization. | 0.704 |