STRINGSTRING
STM3121 STM3121 STM0293 STM0293 STM0294 STM0294 safA safA rpsV rpsV STM1633 STM1633 STM1634 STM1634 sopA sopA cdd cdd STM2230 STM2230 STM2231 STM2231 STM2240 STM2240 STM3117 STM3117 STM3119 STM3119 STM3123 STM3123 STM3777 STM3777 STM4030 STM4030 STM4449 STM4449 STM4489 STM4489
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STM3121Putative transcriptional regulator (gi|5852589); Belongs to the LysR transcriptional regulatory family. (292 aa)
STM0293Putative cytoplasmic protein. (148 aa)
STM0294Putative cytoplasmic protein. (145 aa)
safAPutative outer membrane protein. (170 aa)
rpsV30S ribosomal subunit protein S22; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein. Belongs to the SRA family. (47 aa)
STM1633Similar to E. coli putative periplasmic binding transport protein (AAC74987.1); Blastp hit to AAC74987.1 (266 aa), 25% identity in aa 19 - 232. (253 aa)
STM1634Putative amino acid ABC transporter permease component; Similar to E. coli putative transport system permease protein (former yecC) (AAC74985.1); Blastp hit to AAC74985.1 (222 aa), 31% identity in aa 14 - 213. (215 aa)
sopASecreted effector protein of Salmonella; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway. Required for inducing polymorphonuclear leukocytes migration across the intestinal epithelium. Preferentially uses host UBE2D1 (UBCH5A), UBE2D2 (UBCH5B) and UBE2L3 (UBCH7) as E2 ubiquitin-conjugating enzymes. (782 aa)
cddCytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (294 aa)
STM2230Putative peptidase; Similar to E. coli SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC (AAC74267.1); Blastp hit to AAC74267.1 (139 aa), 38% identity in aa 22 - 139; Belongs to the peptidase S24 family. (167 aa)
STM2231ssrB-regulated factor; Similar to msgA; virulence protein msga (SW:MSGA_SALTY). (96 aa)
STM2240Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74633.1); Blastp hit to AAC74633.1 (362 aa), 84% identity in aa 251 - 362, 43% identity in aa 14 - 238. (329 aa)
STM3117Putative lactoylglutathione lyase; Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidoglycan layer of the cell wall. (144 aa)
STM3119Putative monoamine oxidase; Similar to E. coli putative aldehyde dehydrogenase (AAC74469.1); Blastp hit to AAC74469.1 (681 aa), 29% identity in aa 530 - 661. (175 aa)
STM3123Similar to E. coli putative arylsulfatase regulator (AAC76803.1); Blastp hit to AAC76803.1 (411 aa), 36% identity in aa 4 - 248, 34% identity in aa 230 - 387. (394 aa)
STM3777Putative cytoplasmic protein. (119 aa)
STM4030Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76117.1); Blastp hit to AAC76117.1 (138 aa), 45% identity in aa 19 - 138. (148 aa)
STM4449Putative copG family helix-turn-helix protein; Similar to E. coli negative regulator of translation (AAC74637.1); Blastp hit to AAC74637.1 (79 aa), 46% identity in aa 1 - 79. (80 aa)
STM4489Putative superfamily I DNA helicases; Similar to E. coli putative frameshift suppressor (AAC77264.1); Blastp hit to AAC77264.1 (338 aa), 68% identity in aa 1 - 338. (1171 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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