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pduD pduD pflF pflF pduA pduA pduJ pduJ pduK pduK pduL pduL pduO pduO pduP pduP pduQ pduQ pduS pduS pduT pduT pduV pduV ackA ackA eutL eutL eutC eutC eutA eutA eutG eutG eutE eutE eutN eutN eutD eutD eutT eutT eutS eutS mreB mreB aldB aldB polA polA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pduDPropanediol utilization dehydratase, medium subunit; Part of the PduCDE complex that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. Is required for S.typhimurium growth on 1,2-propanediol as the sole carbon and energy source. (224 aa)
pflFSimilar to E. coli putative formate acetyltransferase (AAC73910.1); Blastp hit to AAC73910.1 (810 aa), 95% identity in aa 1 - 810. (810 aa)
pduAPolyhedral bodies; propanediol utilization protein PDUA. (SW:PDUA_SALTY). (94 aa)
pduJPropanediol utilization protein; Polyhedral bodies; similar to E. coli detox protein (AAC75510.1); Blastp hit to AAC75510.1 (111 aa), 64% identity in aa 17 - 101. (91 aa)
pduKPropanediol utilization protein; Polyhedral bodies; similar to E. coli detox protein (AAC75510.1); Blastp hit to AAC75510.1 (111 aa), 35% identity in aa 9 - 92. (160 aa)
pduLPropanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. Is also able to catalyze the reverse reaction. To a lesser extent, also displays phosphate acetyltransferase activity. Belongs to the PduL family. (210 aa)
pduOPropanediol utilization B12 related protein; Belongs to the Cob(I)alamin adenosyltransferase family. (336 aa)
pduPPropanediol utilization CoA-dependent propionaldehyde dehydrogenase; Similar to E. coli ethanolamine utilization; similar to acetaldehyde dehydrogenase (AAC75508.1); Blastp hit to AAC75508.1 (467 aa), 45% identity in aa 1 - 466. (464 aa)
pduQPropanediol utilization propanol dehydrogenase; Similar to E. coli CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; pyruvate-formate-lyase deactivase (AAC74323.1); Blastp hit to AAC74323.1 (891 aa), 40% identity in aa 574 - 860, 35% identity in aa 456 - 556. (370 aa)
pduSPropanediol utilization protein; Polyhedral bodies; similar to E. coli putative membrane protein (AAC74701.1); Blastp hit to AAC74701.1 (740 aa), 33% identity in aa 131 - 448, 37% identity in aa 33 - 93. (451 aa)
pduTPropanediol utilization protein; Polyhedral bodies; similar to E. coli detox protein (AAC75510.1); Blastp hit to AAC75510.1 (111 aa), 41% identity in aa 16 - 93, 31% identity in aa 16 - 90. (184 aa)
pduVPropanediol utilization protein PDUV. (SW:PDUV_SALTY). (150 aa)
ackAAcetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. (400 aa)
eutLPutative carboxysome structural protein; May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place; Belongs to the EutL/PduB family. (219 aa)
eutCEthanolamine ammonia-lyase, light chain; Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. (298 aa)
eutACPPZ-55 prophage protein; May protect the EutBC lyase from inhibition. (467 aa)
eutGPutative transport protein in ethanolamine utilization; May act on the acetaldehyde produced from the degradation of ethanolamine; Belongs to the iron-containing alcohol dehydrogenase family. (395 aa)
eutEPutative aldehyde oxidoreductase in ethanolamine utilization; May act as an acetaldehyde dehydrogenase that converts acetaldehyde into acetyl-CoA. (467 aa)
eutNPutative detox protein in ethanolamine utilization; May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place; To cyanobacterial carbon dioxide concentrating mechanism protein CcmL. (99 aa)
eutDEthanolamine utilization protein EUTD. (SW:EUTD_SALTY). (338 aa)
eutTPutative ethanolamine utilization cobalamin adenosyltransferase; Converts CNB12 to ADOB12. (267 aa)
eutSPutative ethanol utilization carboxysome structural protein; May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place; Belongs to the EutS/PduU family. (111 aa)
mreBRod shape-determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature. (347 aa)
aldBLactaldehyde dehydrogenase; similar to E. coli aldehyde dehydrogenase B (lactaldehyde dehydrogenase) (AAC76612.1); Blastp hit to AAC76612.1 (542 aa), 96% identity in aa 31 - 542. (512 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template. (928 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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