node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
metB | metC | STM4100 | STM3161 | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | Cystathionine beta-lyase; Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. | 0.968 |
metB | metE | STM4100 | STM3965 | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.991 |
metB | metF | STM4100 | STM4105 | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | 5,10-methylenetetrahydrofolate reductase. (SW:METF_SALTY); Belongs to the methylenetetrahydrofolate reductase family. | 0.979 |
metB | metG | STM4100 | STM2155 | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.403 |
metB | metJ | STM4100 | STM4099 | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | Transcriptional repressor of all met genes but metF; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. It is also autoregulated (By similarity); Belongs to the MetJ family. | 0.972 |
metC | metB | STM3161 | STM4100 | Cystathionine beta-lyase; Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | 0.968 |
metC | metE | STM3161 | STM3965 | Cystathionine beta-lyase; Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.994 |
metC | metF | STM3161 | STM4105 | Cystathionine beta-lyase; Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. | 5,10-methylenetetrahydrofolate reductase. (SW:METF_SALTY); Belongs to the methylenetetrahydrofolate reductase family. | 0.957 |
metC | metJ | STM3161 | STM4099 | Cystathionine beta-lyase; Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. | Transcriptional repressor of all met genes but metF; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. It is also autoregulated (By similarity); Belongs to the MetJ family. | 0.913 |
metE | metB | STM3965 | STM4100 | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | 0.991 |
metE | metC | STM3965 | STM3161 | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Cystathionine beta-lyase; Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. | 0.994 |
metE | metF | STM3965 | STM4105 | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 5,10-methylenetetrahydrofolate reductase. (SW:METF_SALTY); Belongs to the methylenetetrahydrofolate reductase family. | 0.996 |
metE | metG | STM3965 | STM2155 | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.932 |
metE | metJ | STM3965 | STM4099 | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Transcriptional repressor of all met genes but metF; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. It is also autoregulated (By similarity); Belongs to the MetJ family. | 0.899 |
metF | metB | STM4105 | STM4100 | 5,10-methylenetetrahydrofolate reductase. (SW:METF_SALTY); Belongs to the methylenetetrahydrofolate reductase family. | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | 0.979 |
metF | metC | STM4105 | STM3161 | 5,10-methylenetetrahydrofolate reductase. (SW:METF_SALTY); Belongs to the methylenetetrahydrofolate reductase family. | Cystathionine beta-lyase; Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. | 0.957 |
metF | metE | STM4105 | STM3965 | 5,10-methylenetetrahydrofolate reductase. (SW:METF_SALTY); Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.996 |
metF | metG | STM4105 | STM2155 | 5,10-methylenetetrahydrofolate reductase. (SW:METF_SALTY); Belongs to the methylenetetrahydrofolate reductase family. | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.434 |
metF | metJ | STM4105 | STM4099 | 5,10-methylenetetrahydrofolate reductase. (SW:METF_SALTY); Belongs to the methylenetetrahydrofolate reductase family. | Transcriptional repressor of all met genes but metF; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. It is also autoregulated (By similarity); Belongs to the MetJ family. | 0.954 |
metG | metB | STM2155 | STM4100 | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Similar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. | 0.403 |