Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hilC | hilD | STM2867 | STM2875 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | 0.692 |
| hilC | invA | STM2867 | STM2896 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | 0.649 |
| hilC | invC | STM2867 | STM2894 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Surface presentation of antigens; Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells. | 0.504 |
| hilC | invF | STM2867 | STM2899 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Invasion protein; Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.957 |
| hilC | invG | STM2867 | STM2898 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Outer membrane invasion protein; Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane. | 0.599 |
| hilC | invH | STM2867 | STM2900 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Invasion protein; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Pilot protein that is required for the proper localization of the secretin InvG/SctC in the outer membrane. Required for the secretion of the Sip virulence factors. | 0.688 |
| hilC | prgH | STM2867 | STM2874 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Cell invasion protein; Required for invasion of epithelial cells. | 0.936 |
| hilC | prgI | STM2867 | STM2873 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Cytoplasmic cell invasion protein; Required for invasion of epithelial cells; Belongs to the MxiH/PrgI/YscF family. | 0.779 |
| hilC | prgK | STM2867 | STM2871 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Cell invasion protein; Required for invasion of epithelial cells. Could be involved in protein secretion; Belongs to the YscJ lipoprotein family. | 0.641 |
| hilC | sipA | STM2867 | STM2882 | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | Cell invasion protein; Actin-binding protein that interferes with host cell actin cytoskeleton. It stimulates actin polymerization and counteracts F- actin destabilizing proteins. Potentiates SipC activity; both are required for an efficient bacterial internalization. In vitro, forms a complex with host cell protein T-plastin increasing actin bundling. It inhibits ADF/cofilin-directed depolymerization both by preventing binding of ADF and cofilin and by displacing them from F-actin. Also protects F-actin from gelsolin-directed severing and reanneals gelsolin-severed F-actin fragments; [...] | 0.844 |
| hilD | hilC | STM2875 | STM2867 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | araC family bacterial regulatory helix-turn-helix protein; Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1). | 0.692 |
| hilD | invA | STM2875 | STM2896 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Invasion protein; Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | 0.780 |
| hilD | invC | STM2875 | STM2894 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Surface presentation of antigens; Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells. | 0.664 |
| hilD | invF | STM2875 | STM2899 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Invasion protein; Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with SicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE. | 0.957 |
| hilD | invG | STM2875 | STM2898 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Outer membrane invasion protein; Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane. | 0.635 |
| hilD | invH | STM2875 | STM2900 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Invasion protein; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Pilot protein that is required for the proper localization of the secretin InvG/SctC in the outer membrane. Required for the secretion of the Sip virulence factors. | 0.855 |
| hilD | prgH | STM2875 | STM2874 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Cell invasion protein; Required for invasion of epithelial cells. | 0.978 |
| hilD | prgI | STM2875 | STM2873 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Cytoplasmic cell invasion protein; Required for invasion of epithelial cells; Belongs to the MxiH/PrgI/YscF family. | 0.885 |
| hilD | prgK | STM2875 | STM2871 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Cell invasion protein; Required for invasion of epithelial cells. Could be involved in protein secretion; Belongs to the YscJ lipoprotein family. | 0.786 |
| hilD | sipA | STM2875 | STM2882 | Regulatory helix-turn-helix proteins, araC family; HilD (gi|4455108). | Cell invasion protein; Actin-binding protein that interferes with host cell actin cytoskeleton. It stimulates actin polymerization and counteracts F- actin destabilizing proteins. Potentiates SipC activity; both are required for an efficient bacterial internalization. In vitro, forms a complex with host cell protein T-plastin increasing actin bundling. It inhibits ADF/cofilin-directed depolymerization both by preventing binding of ADF and cofilin and by displacing them from F-actin. Also protects F-actin from gelsolin-directed severing and reanneals gelsolin-severed F-actin fragments; [...] | 0.927 |
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