Putative hydrogenase protein; Similar to E. coli putative DMSO reductase anchor subunit (AAC74662.1); Blastp hit to AAC74662.1 (284 aa), 30% identity in aa 6 - 200.

Similar to E. coli hydrogenase activity (AAC75761.1); Blastp hit to AAC75761.1 (255 aa), 96% identity in aa 1 - 255.

Putative hydrogenase protein; Similar to E. coli putative DMSO reductase anchor subunit (AAC74662.1); Blastp hit to AAC74662.1 (284 aa), 30% identity in aa 6 - 200.

Similar to E. coli involved in electron transport from formate to hydrogen, Fe-S centers (AAC75755.1); Blastp hit to AAC75755.1 (175 aa), 95% identity in aa 1 - 173.

Putative hydrogenase protein; Similar to E. coli putative DMSO reductase anchor subunit (AAC74662.1); Blastp hit to AAC74662.1 (284 aa), 30% identity in aa 6 - 200.

Hydrogenase maturation protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.

L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).

Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.

Transcriptional repressor gnt-I; gntUKR; GalR/LacI family; similar to E. coli regulator of gluconate (gnt) operon (AAC76463.1); Blastp hit to AAC76463.1 (313 aa), 97% identity in aa 1 - 304.

Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.

Response regulator in two-component regulatory system with EnvZ; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (By similarity). Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (By similarity).

Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.

Response regulator in two-component regulatory system with PhoQ; Member of the two-component regulatory system PhoP/PhoQ which regulates the expression of genes involved in virulence, adaptation to acidic and low Mg(2+) environments and resistance to host defense antimicrobial peptides. Essential for intramacrophage survival of S.typhimurium. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repressio [...]

L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).

Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.

ABC superfamily (membrane) heme exporter protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.

Heme exporter protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.

Heme exporter protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.

ABC superfamily (membrane) heme exporter protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.

DAACS family C4-dicarboxylic acids transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.

Dcu family anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.

DAACS family C4-dicarboxylic acids transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.

Regulatory protein P-II 2; Nitrogen assimilation by glutamine synthetase; regulates GlnL (NRII) and GlnE (ATase); similar to E. coli nitrogen regulatory protein P-II 2 (AAC73553.1); Blastp hit to AAC73553.1 (112 aa), 97% identity in aa 1 - 112.

Dcu family anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.

DAACS family C4-dicarboxylic acids transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.

Dcu family anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.

DcuC family, dicarboxylate transporter; Similar to E. coli transport of dicarboxylates (AAC73722.1); Blastp hit to AAC73722.1 (461 aa), 92% identity in aa 1 - 460.

DcuC family, dicarboxylate transporter; Similar to E. coli transport of dicarboxylates (AAC73722.1); Blastp hit to AAC73722.1 (461 aa), 92% identity in aa 1 - 460.

Dcu family anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.

4.5S-RNP protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the [...]

DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state, and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. Replenishes negative supercoiling downstream of highly transcribed genes to help control overall chromosomal supercoiling density. E.coli makes 15% more negative supercoils in pBR322 plasmid DNA than S.typhimurium; the S.typhimurium GyrB s [...]

Formate channel 1; putative FNT family member; similar to E. coli probable formate transporter (formate channel 1) (AAC73990.1); Blastp hit to AAC73990.1 (285 aa), 95% identity in aa 1 - 285.

Similar to E. coli hydrogenase activity (AAC75761.1); Blastp hit to AAC75761.1 (255 aa), 96% identity in aa 1 - 255.

Formate channel 1; putative FNT family member; similar to E. coli probable formate transporter (formate channel 1) (AAC73990.1); Blastp hit to AAC73990.1 (285 aa), 95% identity in aa 1 - 285.

Anaerobic ribonucleoside-triphosphate reductase; Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. Belongs to the anaerobic ribonucleoside-triphosphate reductase family.

Formate channel 1; putative FNT family member; similar to E. coli probable formate transporter (formate channel 1) (AAC73990.1); Blastp hit to AAC73990.1 (285 aa), 95% identity in aa 1 - 285.

Putative formate acetyltransferase; Acts as a radical domain for damaged PFL and possibly other radical proteins.

Regulatory protein (P-II) for nitrogen assimilation by glutamine synthetase (ATase); P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity).

Regulatory protein P-II 2; Nitrogen assimilation by glutamine synthetase; regulates GlnL (NRII) and GlnE (ATase); similar to E. coli nitrogen regulatory protein P-II 2 (AAC73553.1); Blastp hit to AAC73553.1 (112 aa), 97% identity in aa 1 - 112.