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stbE stbE sbp sbp oat oat iroE iroE iroD iroD iroC iroC acrD acrD hisD hisD narX narX asr asr topB topB phoH phoH hha hha ldcC ldcC iroB iroB kgtP kgtP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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stbEPutative fimbriae; Similar to E. coli periplasmic chaperone, required for type 1 fimbriae (AAC77272.1); Blastp hit to AAC77272.1 (241 aa), 30% identity in aa 32 - 241. (252 aa)
sbpSulfate transport protein; This protein specifically binds sulfate and is involved in its transmembrane transport; Belongs to the prokaryotic sulfate-binding protein family. (329 aa)
oatPutative acetylornithine aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (429 aa)
iroEPutative hydrolase of the alpha/beta superfamily. (311 aa)
iroDEnterochelin esterase-like protein (Fes); Similar to E. coli enterochelin esterase (AAC73686.1); Blastp hit to AAC73686.1 (374 aa), 31% identity in aa 3 - 362. (414 aa)
iroCPutative ATP binding cassette (ABC) transporter; Similar to E. coli ATP-binding transport protein; multicopy suppressor of htrB (AAC74000.1); Blastp hit to AAC74000.1 (582 aa), 26% identity in aa 14 - 582, 29% identity in aa 34 - 565. (1217 aa)
acrDRND family aminoglycoside/multidrug efflux pump; Similar to E. coli sensitivity to acriflavine, integral membrane protein, possible efflux pump (AAC75523.1); Blastp hit to AAC75523.1 (1037 aa), 94% identity in aa 1 - 1037. (1037 aa)
hisDHistidinal dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa)
narXSensory histidine kinase in two component regulatory system with NarL; Senses nitrate/nitrite; regulates anaerobic respiration and fermentation; similar to E. coli nitrate/nitrate sensor, histidine protein kinase acts on NarL regulator (AAC74306.1); Blastp hit to AAC74306.1 (598 aa), 86% identity in aa 1 - 598. (598 aa)
asrAcid shock protein; Required for growth and/or survival at acidic conditions. (94 aa)
topBDNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] (649 aa)
phoHSimilar to E. coli PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation (AAC74105.1); Blastp hit to AAC74105.1 (354 aa), 92% identity in aa 71 - 354. (284 aa)
hhaHemolysin expression modulating protein (involved in environmental regulation of virulence factors); Interacts with H-NS and in this complex might contact DNA, which could provide an additional surface for DNA binding to the H-NS- Hha complex; may not bind DNA in the absence of H-NS. In vitro improves the ability of H-NS to bind DNA under a precise set of conditions. (72 aa)
ldcCSimilar to E. coli lysine decarboxylase 2, constitutive (AAC73297.1); Blastp hit to AAC73297.1 (713 aa), 91% identity in aa 1 - 712. (713 aa)
iroBPutative glycosyl transferase; Related to UDP-glucuronosyltransferase. (371 aa)
kgtPSimilar to E. coli alpha-ketoglutarate permease (AAC75640.1); Blastp hit to AAC75640.1 (432 aa), 88% identity in aa 1 - 432. (433 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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