STRINGSTRING
glk glk pgm pgm csgD csgD zwf zwf dgcQ dgcQ bglX bglX pckA pckA bcsC bcsC yhjN yhjN yhjQ yhjQ yhjS yhjS pgi pgi
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glkGlucokinase; Similar to E. coli glucokinase (AAC75447.1); Blastp hit to AAC75447.1 (321 aa), 93% identity in aa 1 - 321; Belongs to the bacterial glucokinase family. (321 aa)
pgmPhosphoglucomutase; Similar to E. coli phosphoglucomutase (AAC73782.1); Blastp hit to AAC73782.1 (546 aa), 97% identity in aa 1 - 546. (546 aa)
csgDPutative transcriptional regulator; Necessary for transcription of the csgAB operon. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription (By similarity). (216 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
dgcQPutative inner membrane protein; Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Involved in the regulation of cellulose production (By similarity). (570 aa)
bglXPeriplasmic beta-D-glucoside glucohydrolase; Periplasmic beta-glucosidase precursor. (SW:BGLX_SALTY); Belongs to the glycosyl hydrolase 3 family. (765 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (539 aa)
bcsCendo-1,4-D-glucanase; Hydrolyzes carboxymethylcellulose; Belongs to the glycosyl hydrolase 8 (cellulase D) family. (369 aa)
yhjNPutative cellulose synthase; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. (766 aa)
yhjQPutative ATPase involved in chromosome partitioning; Essential for cellulose biosynthesis. May play a role in subcellular localization of an active cellulose biosynthesis apparatus at the bacterial cell pole (By similarity); Belongs to the BcsQ family. (250 aa)
yhjSPutative cytoplasmic protein; Required for cellulose biosynthesis. May have protease activity , but BcsA is not targeted. Binds bis-(3'-5') cyclic diguanylic acid (c-di-GMP) ; Belongs to the BcsE family. (523 aa)
pgiSimilar to E. coli glucosephosphate isomerase (AAC76995.1); Blastp hit to AAC76995.1 (549 aa), 95% identity in aa 1 - 548. (549 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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