STRINGSTRING
yhgG yhgG fhuE fhuE rstB rstB rstA rstA tonB tonB exbD exbD exbB exbB feoA feoA feoB feoB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yhgGPutative cytoplasmic protein; May function as a transcriptional regulator that controls feoABC expression. (78 aa)
fhuEOuter membrane receptor for Fe(III)-coprogen; Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid uptake; similar to E. coli outer membrane receptor for ferric iron uptake (AAC74186.1); Blastp hit to AAC74186.1 (729 aa), 81% identity in aa 5 - 729. (724 aa)
rstBSensory histidine kinase in two-component regulatory system with RstA; Similar to E. coli sensor histidine protein kinase (RstA regulator) (AAC74681.1); Blastp hit to AAC74681.1 (433 aa), 82% identity in aa 1 - 433. (433 aa)
rstASimilar to E. coli response transcriptional regulatory protein (RstB sensor) (AAC74680.1); Blastp hit to AAC74680.1 (242 aa), 84% identity in aa 4 - 242. (243 aa)
tonBTonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates such as cobalamin, and various iron compounds (such as iron dicitrate, enterochelin, aerobactin, etc.). In the absence of TonB these receptors bind their substrates but do not carry out active transport. TonB also interacts with some colicins and is involved in the energy-dependent, irreversible steps of bacteriophages phi 80 and T1 infection. It could act to transduce energy from the cytoplasmic membrane to specific en [...] (242 aa)
exbDtonB-dependent uptake of B colicins; similar to E. coli uptake of enterochelin; tonB-dependent uptake of B colicins (AAC76041.1); Blastp hit to AAC76041.1 (141 aa), 93% identity in aa 1 - 141. (141 aa)
exbBUptake of enterochelin; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity). (244 aa)
feoASimilar to E. coli ferrous iron transport protein A (AAC76433.1); Blastp hit to AAC76433.1 (75 aa), 96% identity in aa 1 - 75. (75 aa)
feoBFerrous iron transport protein B; Probable transporter for a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (772 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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