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gntR gntR yhjC yhjC yiaG yiaG yiaJ yiaJ yidC yidC yieP yieP rho rho yihW yihW yijO yijO iclR iclR hfq hfq ytfH ytfH araC araC dksA dksA yafC yafC ybaO ybaO fimA fimA ybdO ybdO ybeF ybeF nagC nagC deoR deoR ydhB ydhB ynfL ynfL yneJ yneJ ydcR ydcR ydcI ydcI fliA fliA yeeY yeeY yegW yegW yfeC yfeC yfeD yfeD yfhH yfhH yfiE yfiE galR galR ygbI ygbI yhaJ yhaJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gntRTranscriptional repressor gnt-I; gntUKR; GalR/LacI family; similar to E. coli regulator of gluconate (gnt) operon (AAC76463.1); Blastp hit to AAC76463.1 (313 aa), 97% identity in aa 1 - 304. (331 aa)
yhjCSimilar to E. coli putative transcriptional regulator LYSR-type (AAC76546.1); Blastp hit to AAC76546.1 (323 aa), 66% identity in aa 25 - 320; Belongs to the LysR transcriptional regulatory family. (299 aa)
yiaGPutative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC76579.1); Blastp hit to AAC76579.1 (96 aa), 79% identity in aa 1 - 96. (96 aa)
yiaJIclR family transcriptional repressor; Similar to E. coli putative regulator (AAC76598.1); Blastp hit to AAC76598.1 (282 aa), 91% identity in aa 16 - 276. (266 aa)
yidCPutative preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (548 aa)
yiePPutative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC76778.1); Blastp hit to AAC76778.1 (181 aa), 82% identity in aa 1 - 181. (234 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa)
yihWPutative glycerol-3-phosphate regulon repressor; DeoR family; similar to E. coli putative DEOR-type transcriptional regulator (AAD13446.1); Blastp hit to AAD13446.1 (269 aa), 89% identity in aa 9 - 263. (267 aa)
yijOSimilar to E. coli putative ARAC-type regulatory protein (AAC76936.1); Blastp hit to AAC76936.1 (283 aa), 89% identity in aa 1 - 282. (283 aa)
iclRAcetate operon transcriptional repressor; Regulation of the glyoxylate bypass operon, which encodes isocitrate lyase, malate synthase as well as isocitrate dehydrogenase kinase/phosphorylase. (274 aa)
hfqHost factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Plays a central regulatory role in the microbial response to space flight conditions. Is essential for virulence and is required for efficient invasion of non-phagocytic cells. (102 aa)
ytfHPutative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC77169.1); Blastp hit to AAC77169.1 (156 aa), 90% identity in aa 35 - 152. (128 aa)
araCTranscriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. (281 aa)
dksAdnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. (151 aa)
yafCSimilar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 90% identity in aa 1 - 303; Belongs to the LysR transcriptional regulatory family. (304 aa)
ybaOSimilar to E. coli putative LRP-like transcriptional regulator (AAC73550.1); Blastp hit to AAC73550.1 (181 aa), 95% identity in aa 30 - 181. (152 aa)
fimAMajor type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs; Belongs to the fimbrial protein family. (185 aa)
ybdOSimilar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. (300 aa)
ybeFSimilar to E. coli putative transcriptional regulator LYSR-type (AAC73730.1); Blastp hit to AAC73730.1 (266 aa), 68% identity in aa 1 - 266; Belongs to the LysR transcriptional regulatory family. (317 aa)
nagCSimilar to E. coli transcriptional repressor of nag (N-acetylglucosamine) operon (AAC73770.1); Blastp hit to AAC73770.1 (406 aa), 94% identity in aa 1 - 406. (406 aa)
deoRSimilar to E. coli transcriptional repressor for deo operon, tsx, nupG (AAC73927.1); Blastp hit to AAC73927.1 (252 aa), 83% identity in aa 1 - 252. (252 aa)
ydhBSimilar to E. coli putative transcriptional regulator LYSR-type (AAC74731.1); Blastp hit to AAC74731.1 (310 aa), 90% identity in aa 1 - 310; Belongs to the LysR transcriptional regulatory family. (310 aa)
ynfLSimilar to E. coli putative transcriptional regulator LYSR-type (AAC74667.1); Blastp hit to AAC74667.1 (297 aa), 83% identity in aa 1 - 297; Belongs to the LysR transcriptional regulatory family. (299 aa)
yneJSimilar to E. coli putative transcriptional regulator LYSR-type (AAC74599.1); Blastp hit to AAC74599.1 (293 aa), 84% identity in aa 1 - 283; Belongs to the LysR transcriptional regulatory family. (290 aa)
ydcRPutative gntR family regulatory protein; Similar to E. coli multi modular; putative transcriptional regulator; also putative ATP-binding component of a transport system (AAC74521.1); Blastp hit to AAC74521.1 (468 aa), 87% identity in aa 1 - 468. (474 aa)
ydcISimilar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 83% identity in aa 48 - 353; Belongs to the LysR transcriptional regulatory family. (307 aa)
fliASigma F (sigma 28) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. May regulate the expression of genes involved in virulence. (239 aa)
yeeYSimilar to E. coli putative transcriptional regulator LYSR-type (AAC75076.1); Blastp hit to AAC75076.1 (316 aa), 87% identity in aa 8 - 309; Belongs to the LysR transcriptional regulatory family. (304 aa)
yegWPutative gntR family regulatory protein; Similar to E. coli putative transcriptional regulator (AAC75162.1); Blastp hit to AAC75162.1 (248 aa), 92% identity in aa 1 - 248. (248 aa)
yfeCPutative negative regulator; Similar to E. coli orf, hypothetical protein (AAC75455.1); Blastp hit to AAC75455.1 (119 aa), 79% identity in aa 1 - 119. (120 aa)
yfeDPutative negative regulator; Similar to E. coli orf, hypothetical protein (AAC75456.1); Blastp hit to AAC75456.1 (130 aa), 70% identity in aa 1 - 129. (130 aa)
yfhHPutative ABC superfamily transport protein; Membrane; similar to E. coli orf, hypothetical protein (AAC75614.1); Blastp hit to AAC75614.1 (306 aa), 83% identity in aa 25 - 306. (282 aa)
yfiESimilar to E. coli putative transcriptional regulator LYSR-type (AAC75630.1); Blastp hit to AAC75630.1 (308 aa), 78% identity in aa 16 - 305; Belongs to the LysR transcriptional regulatory family. (299 aa)
galRTranscriptional repressor of galETK operon; Repressor of the galactose operon. Binds galactose as an inducer (By similarity). (342 aa)
ygbIPutative regulatory protein, deoR family; Similar to E. coli putative DEOR-type transcriptional regulator (AAC75777.1); Blastp hit to AAC75777.1 (265 aa), 86% identity in aa 11 - 263. (254 aa)
yhaJSimilar to E. coli putative transcriptional regulator LYSR-type (AAC76140.1); Blastp hit to AAC76140.1 (298 aa), 96% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. (298 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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