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oxyR | Regulatory protein sensor for oxidative stress; Regulates intracellular hydrogen peroxide (LysR family); similar to E. coli activator, hydrogen peroxide-inducible genes (AAC76943.1); Blastp hit to AAC76943.1 (305 aa), 95% identity in aa 1 - 305; Belongs to the LysR transcriptional regulatory family. (305 aa) | ||||
malE | Maltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. (399 aa) | ||||
hfq | Host factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Plays a central regulatory role in the microbial response to space flight conditions. Is essential for virulence and is required for efficient invasion of non-phagocytic cells. (102 aa) | ||||
rof | Modulator of Rho-dependent transcription termination; Similar to E. coli orf, hypothetical protein (AAC73300.1); Blastp hit to AAC73300.1 (86 aa), 81% identity in aa 1 - 86. (86 aa) | ||||
rnhA | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (155 aa) | ||||
ybaK | Putative cytoplasmic protein; Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. (159 aa) | ||||
ahpC | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa) | ||||
ahpF | Alkyl hydroperoxide reductase, F52a subunit; Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. (521 aa) | ||||
ybiT | Putative ATPase component of ABC transporter with duplicated ATPase domain; Similar to E. coli putative ATP-binding component of a transport system (AAC73907.1); Blastp hit to AAC73907.1 (530 aa), 96% identity in aa 1 - 530. (530 aa) | ||||
uup | Contains duplicated ATPase domain; similar to E. coli putative ATP-binding component of a transport system (AAC74035.1); Blastp hit to AAC74035.1 (635 aa), 94% identity in aa 1 - 634. (635 aa) | ||||
rne | RNase E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1067 aa) | ||||
katE | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (750 aa) | ||||
ssrA | Secretion system regulator: Sensor component; SpiR (gi|1498305). (920 aa) | ||||
pspA | Phage shock protein; Negative regulatory gene for the psp opreon; similar to E. coli phage shock protein, inner membrane protein (AAC74386.1); Blastp hit to AAC74386.1 (222 aa), 91% identity in aa 1 - 222. (222 aa) | ||||
pspF | Similar to E. coli psp operon transcriptional activator (AAC74385.1); Blastp hit to AAC74385.1 (330 aa), 86% identity in aa 6 - 330. (326 aa) | ||||
yobF | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74894.1); Blastp hit to AAC74894.1 (47 aa), 93% identity in aa 1 - 47. (47 aa) | ||||
pykA | Pyruvate kinase II; Glucose stimulated; similar to E. coli pyruvate kinase II, glucose stimulated (AAC74924.1); Blastp hit to AAC74924.1 (480 aa), 98% identity in aa 1 - 480. (480 aa) | ||||
yfhP | Hypothetical protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (164 aa) | ||||
srmB | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (444 aa) | ||||
ygdP | Putative invasion protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (176 aa) | ||||
vapC | Putative nucleic acid-binding protein; Toxic component of a type II toxin-antitoxin (TA) system. A site-specific tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Does not cleave tRNA(Met), tRNA(Arg2), tRNA(His), tRNA(Leu), tRNA(Phe) tRNA(Thr1), tRNA(Tyr) or tRNA(Val). Overexpression in E.coli inhibits translation, leads to loss of cell growth and degradation of tRNA(fMet), these effects are neutralized by expression of cognate antitoxin VapB. Expression also activates translation initiation at c [...] (132 aa) | ||||
fusA | Protein chain elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPas [...] (704 aa) | ||||
yheS | Contains duplicated ATPase domain; similar to E. coli putative ATP-binding component of a transport system (AAC76377.1); Blastp hit to AAC76377.1 (637 aa), 93% identity in aa 1 - 631. (635 aa) | ||||
rtcA | RNA 3'-terminal phosphate cyclase (with b3419); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (339 aa) | ||||
rtcB | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76446.1); Blastp hit to AAC76446.1 (408 aa), 87% identity in aa 1 - 408. (405 aa) | ||||
rtcR | Sigma N (sigma 54)-dependent regulator of rtcBA expression; EBP family; similar to E. coli putative 2-component regulator (AAC76447.1); Blastp hit to AAC76447.1 (532 aa), 84% identity in aa 1 - 527. (527 aa) | ||||
cyaA | Adenylate cyclase. (SW:CYAA_SALTY). (848 aa) | ||||
katG | Catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (726 aa) |