STRINGSTRING
cfa cfa STM1330 STM1330 STM1633 STM1633 STM1634 STM1634 STM1635 STM1635 araH araH pocR pocR sopA sopA vapC vapC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cfaSimilar to E. coli cyclopropane fatty acyl phospholipid synthase (AAC74733.1); Blastp hit to AAC74733.1 (382 aa), 90% identity in aa 1 - 382. (382 aa)
STM1330Putative DNA/RNA non-specific endonuclease. (284 aa)
STM1633Similar to E. coli putative periplasmic binding transport protein (AAC74987.1); Blastp hit to AAC74987.1 (266 aa), 25% identity in aa 19 - 232. (253 aa)
STM1634Putative amino acid ABC transporter permease component; Similar to E. coli putative transport system permease protein (former yecC) (AAC74985.1); Blastp hit to AAC74985.1 (222 aa), 31% identity in aa 14 - 213. (215 aa)
STM1635Putative ABC-type polar amino acid transport system; ATPase component; similar to E. coli putative ATP-binding component of a transport system (AAC76303.1); Blastp hit to AAC76303.1 (252 aa), 42% identity in aa 11 - 230. (243 aa)
araHPutative intracellular protease/amidase; Similar to E. coli 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis (AAC73527.1); Blastp hit to AAC73527.1 (198 aa), 30% identity in aa 9 - 183. (185 aa)
pocRPropanediol utilization protein; Positive regulatory protein of pdu and cob operons. (303 aa)
sopASecreted effector protein of Salmonella; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway. Required for inducing polymorphonuclear leukocytes migration across the intestinal epithelium. Preferentially uses host UBE2D1 (UBCH5A), UBE2D2 (UBCH5B) and UBE2L3 (UBCH7) as E2 ubiquitin-conjugating enzymes. (782 aa)
vapCPutative nucleic acid-binding protein; Toxic component of a type II toxin-antitoxin (TA) system. A site-specific tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Does not cleave tRNA(Met), tRNA(Arg2), tRNA(His), tRNA(Leu), tRNA(Phe) tRNA(Thr1), tRNA(Tyr) or tRNA(Val). Overexpression in E.coli inhibits translation, leads to loss of cell growth and degradation of tRNA(fMet), these effects are neutralized by expression of cognate antitoxin VapB. Expression also activates translation initiation at c [...] (132 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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