12 items (Salmonella enterica Typhimurium) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

co-expression

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Your Input:
	ompR	Response regulator in two-component regulatory system with EnvZ; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (By similarity). Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (By similarity). (239 aa)
	rpoA	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
	rpoB	RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa)
	pstS	High-affinity phosphate transporter; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
	yfcF	Putative glutathione-S-transferase; Similar to E. coli orf, hypothetical protein (AAC75361.1); Blastp hit to AAC75361.1 (214 aa), 80% identity in aa 1 - 214. (214 aa)
	gst	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200. (201 aa)
	yliJ	Putative glutathione S-transferase; Similar to E. coli putative transferase (AAC73925.1); Blastp hit to AAC73925.1 (210 aa), 82% identity in aa 3 - 210. (208 aa)
	kdpE	Response regulator in two-component regulatory system with KdpD; Regulates kdp operon encoding a high-affinity K translocating ATPase (OmpR family); similar to E. coli regulator of kdp operon (transcriptional effector) (AAC73788.1); Blastp hit to AAC73788.1 (225 aa), 91% identity in aa 1 - 224. (225 aa)
	phoB	Regulates pho regulon (OmpR family); similar to E. coli positive response regulator for pho regulon, sensor is PhoR (or CreC) (AAC73502.1); Blastp hit to AAC73502.1 (229 aa), 95% identity in aa 1 - 229. (229 aa)
	rpoC	RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa)
	STM4267	Putative glutathione S-transferase; Belongs to the GST superfamily. (222 aa)
	basR	Response regulator in two-component regulatory system with BasS; Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd, ais, arnBCADTEF and eptA-basRS loci, all involved in resistance to polymyxin. Represses the transcription of pmrD. Plays a role in the adaptation of the organism to the host environment, in particular to neutrophils, and therefore it plays a role in virulence as well. (222 aa)

Your Current Organism:

Salmonella enterica Typhimurium

NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
STM4267	gst	STM4267	STM1451	Putative glutathione S-transferase; Belongs to the GST superfamily.	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200.	0.912
STM4267	rpoA	STM4267	STM3415	Putative glutathione S-transferase; Belongs to the GST superfamily.	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.634
STM4267	rpoB	STM4267	STM4153	Putative glutathione S-transferase; Belongs to the GST superfamily.	RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.402
STM4267	rpoC	STM4267	STM4154	Putative glutathione S-transferase; Belongs to the GST superfamily.	RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.445
STM4267	yfcF	STM4267	STM2348	Putative glutathione S-transferase; Belongs to the GST superfamily.	Putative glutathione-S-transferase; Similar to E. coli orf, hypothetical protein (AAC75361.1); Blastp hit to AAC75361.1 (214 aa), 80% identity in aa 1 - 214.	0.901
STM4267	yliJ	STM4267	STM0862	Putative glutathione S-transferase; Belongs to the GST superfamily.	Putative glutathione S-transferase; Similar to E. coli putative transferase (AAC73925.1); Blastp hit to AAC73925.1 (210 aa), 82% identity in aa 3 - 210.	0.915
gst	STM4267	STM1451	STM4267	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200.	Putative glutathione S-transferase; Belongs to the GST superfamily.	0.912
gst	rpoA	STM1451	STM3415	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200.	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.620
gst	rpoB	STM1451	STM4153	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200.	RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.402
gst	rpoC	STM1451	STM4154	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200.	RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.445
gst	yfcF	STM1451	STM2348	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200.	Putative glutathione-S-transferase; Similar to E. coli orf, hypothetical protein (AAC75361.1); Blastp hit to AAC75361.1 (214 aa), 80% identity in aa 1 - 214.	0.925
gst	yliJ	STM1451	STM0862	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200.	Putative glutathione S-transferase; Similar to E. coli putative transferase (AAC73925.1); Blastp hit to AAC73925.1 (210 aa), 82% identity in aa 3 - 210.	0.926
phoB	pstS	STM0397	STM3857	Regulates pho regulon (OmpR family); similar to E. coli positive response regulator for pho regulon, sensor is PhoR (or CreC) (AAC73502.1); Blastp hit to AAC73502.1 (229 aa), 95% identity in aa 1 - 229.	High-affinity phosphate transporter; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.	0.819
pstS	phoB	STM3857	STM0397	High-affinity phosphate transporter; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.	Regulates pho regulon (OmpR family); similar to E. coli positive response regulator for pho regulon, sensor is PhoR (or CreC) (AAC73502.1); Blastp hit to AAC73502.1 (229 aa), 95% identity in aa 1 - 229.	0.819
rpoA	STM4267	STM3415	STM4267	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Putative glutathione S-transferase; Belongs to the GST superfamily.	0.634
rpoA	gst	STM3415	STM1451	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Similar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200.	0.620
rpoA	rpoB	STM3415	STM4153	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoA	rpoC	STM3415	STM4154	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoA	yfcF	STM3415	STM2348	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Putative glutathione-S-transferase; Similar to E. coli orf, hypothetical protein (AAC75361.1); Blastp hit to AAC75361.1 (214 aa), 80% identity in aa 1 - 214.	0.628
rpoA	yliJ	STM3415	STM0862	RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Putative glutathione S-transferase; Similar to E. coli putative transferase (AAC73925.1); Blastp hit to AAC73925.1 (210 aa), 82% identity in aa 3 - 210.	0.634

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