STRINGSTRING
ydiM ydiM ynfM ynfM menD menD yfcJ yfcJ yfcL yfcL trxC trxC pheA pheA yhhS yhhS yhjE yhjE trxA trxA cybC cybC yjjG yjjG yjeS yjeS yadB yadB fhuA fhuA fhuC fhuC araJ araJ cyoD cyoD cyoC cyoC cyoB cyoB cyoA cyoA fepA fepA fes fes fepB fepB cydB cydB aroA aroA ycfJ ycfJ STM1269 STM1269 aroD aroD ydiB ydiB ydiN ydiN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ydiMSimilar to E. coli putative transport system permease protein (AAC74760.1); Blastp hit to AAC74760.1 (404 aa), 79% identity in aa 1 - 395. (403 aa)
ynfMSimilar to E. coli putative transport protein (AAC74668.1); Blastp hit to AAC74668.1 (417 aa), 91% identity in aa 1 - 417. (417 aa)
menD2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (556 aa)
yfcJSimilar to E. coli putative transport protein (AAC75382.1); Blastp hit to AAC75382.1 (392 aa), 88% identity in aa 1 - 392. (392 aa)
yfcLPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75385.1); Blastp hit to AAC75385.1 (92 aa), 85% identity in aa 1 - 91. (91 aa)
trxCSimilar to E. coli putative thioredoxin-like protein (AAC75635.1); Blastp hit to AAC75635.1 (139 aa), 94% identity in aa 1 - 139; Belongs to the thioredoxin family. (139 aa)
pheAChorismate mutase P; Bifuctional; similar to E. coli chorismate mutase-P and prephenate dehydratase (AAC75648.1); Blastp hit to AAC75648.1 (386 aa), 90% identity in aa 1 - 385. (386 aa)
yhhSPutative MFS family transport protein; Similar to E. coli putative transport (AAC76498.1); Blastp hit to AAC76498.1 (419 aa), 89% identity in aa 1 - 419. (419 aa)
yhjESimilar to E. coli putative transport protein (AAC76548.1); Blastp hit to AAC76548.1 (440 aa), 94% identity in aa 1 - 440. (440 aa)
trxAThioredoxin 1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Belongs to the thioredoxin family. (109 aa)
cybCCytochrome b(562); Electron-transport protein of unknown function. (128 aa)
yjjGPutative haloacid dehalogenase-like hydrolase; Similar to E. coli putative phosphatase (AAC77327.1); Blastp hit to AAC77327.1 (225 aa), 91% identity in aa 1 - 225. (226 aa)
yjeSPutative Fe-S protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (384 aa)
yadBPutative glutamyl t-RNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (313 aa)
fhuAIron complex outermembrane recepter protein; Similar to E. coli outer membrane protein receptor for ferrichrome, colicin M, and phages T1, T5, and phi80 (AAC73261.1); Blastp hit to AAC73261.1 (747 aa), 68% identity in aa 1 - 747. (729 aa)
fhuCHydroxymate-dependent iron transport; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of hydroxymate-dependent iron transport (AAC73262.1); Blastp hit to AAC73262.1 (265 aa), 92% identity in aa 1 - 265. (265 aa)
araJMFS family, arabinose polymer transporter; Similar to E. coli involved in either transport or processing of arabinose polymers (AAC73499.1); Blastp hit to AAC73499.1 (394 aa), 85% identity in aa 1 - 388. (390 aa)
cyoDSimilar to E. coli cytochrome o ubiquinol oxidase subunit IV (AAC73532.1); Blastp hit to AAC73532.1 (109 aa), 93% identity in aa 1 - 109. (109 aa)
cyoCSimilar to E. coli cytochrome o ubiquinol oxidase subunit III (AAC73533.1); Blastp hit to AAC73533.1 (204 aa), 96% identity in aa 1 - 204. (204 aa)
cyoBSimilar to E. coli cytochrome o ubiquinol oxidase subunit I (AAC73534.1); Blastp hit to AAC73534.1 (663 aa), 95% identity in aa 1 - 663; Belongs to the heme-copper respiratory oxidase family. (663 aa)
cyoASimilar to E. coli cytochrome o ubiquinol oxidase subunit II (AAC73535.1); Blastp hit to AAC73535.1 (315 aa), 95% identity in aa 1 - 315. (318 aa)
fepASimilar to E. coli outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D (AAC73685.1); Blastp hit to AAC73685.1 (746 aa), 81% identity in aa 1 - 746. (751 aa)
fesSimilar to E. coli enterochelin esterase (AAC73686.1); Blastp hit to AAC73686.1 (374 aa), 74% identity in aa 2 - 369. (404 aa)
fepBABC superfamily (peri_perm); similar to E. coli ferric enterobactin (enterochelin) binding protein; periplasmic component (AAC73693.1); Blastp hit to AAC73693.1 (318 aa), 79% identity in aa 1 - 318. (318 aa)
cydBSimilar to E. coli cytochrome d terminal oxidase polypeptide subunit II (AAC73828.1); Blastp hit to AAC73828.1 (379 aa), 92% identity in aa 1 - 379. (379 aa)
aroA3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa)
ycfJPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74194.1); Blastp hit to AAC74194.1 (179 aa), 94% identity in aa 1 - 178. (179 aa)
STM1269Putative chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (181 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of a lys-170 at the active site. Belongs to the type-I 3-dehydroquinase family. (252 aa)
ydiBPutative shikimate 5-dehydrogenase; The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD. (288 aa)
ydiNSimilar to E. coli putative amino acid/amine transport protein (AAC74761.1); Blastp hit to AAC74761.1 (423 aa), 85% identity in aa 3 - 412. (411 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.