node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
nadA | nadB | STM0756 | STM2641 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.999 |
nadA | nadR | STM0756 | STM4580 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.969 |
nadA | pncA | STM0756 | STM1293 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | 0.820 |
nadA | pnuC | STM0756 | STM0757 | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | NMN family, nucleoside/purine/pyrimidine transporter; Required for nicotinamide riboside transport across the inner membrane. | 0.993 |
nadB | nadA | STM2641 | STM0756 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.999 |
nadB | nadR | STM2641 | STM4580 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.965 |
nadB | pncA | STM2641 | STM1293 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | 0.910 |
nadB | pnuC | STM2641 | STM0757 | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | NMN family, nucleoside/purine/pyrimidine transporter; Required for nicotinamide riboside transport across the inner membrane. | 0.961 |
nadR | nadA | STM4580 | STM0756 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.969 |
nadR | nadB | STM4580 | STM2641 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.965 |
nadR | pncA | STM4580 | STM1293 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | 0.823 |
nadR | pnuC | STM4580 | STM0757 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | NMN family, nucleoside/purine/pyrimidine transporter; Required for nicotinamide riboside transport across the inner membrane. | 0.987 |
nadR | serB | STM4580 | STM4578 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Similar to E. coli 3-phosphoserine phosphatase (AAC77341.1); Blastp hit to AAC77341.1 (322 aa), 93% identity in aa 1 - 322. | 0.565 |
nadR | trpR | STM4580 | STM4583 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Transcriptional repressor for trp operon and aroH; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | 0.410 |
pncA | nadA | STM1293 | STM0756 | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.820 |
pncA | nadB | STM1293 | STM2641 | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.910 |
pncA | nadR | STM1293 | STM4580 | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.823 |
pncA | pnuC | STM1293 | STM0757 | Nicotinamidase/ pyrazinamidase; Similar to E. coli orf, hypothetical protein (AAC74838.1); Blastp hit to AAC74838.1 (219 aa), 80% identity in aa 7 - 219. | NMN family, nucleoside/purine/pyrimidine transporter; Required for nicotinamide riboside transport across the inner membrane. | 0.899 |
pnuC | nadA | STM0757 | STM0756 | NMN family, nucleoside/purine/pyrimidine transporter; Required for nicotinamide riboside transport across the inner membrane. | Quinolinate synthetase, A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.993 |
pnuC | nadB | STM0757 | STM2641 | NMN family, nucleoside/purine/pyrimidine transporter; Required for nicotinamide riboside transport across the inner membrane. | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.961 |