node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
invJ | sipB | STM2892 | STM2885 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | Cell invasion protein; Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chape [...] | 0.984 |
invJ | spaO | STM2892 | STM2891 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.992 |
invJ | spaP | STM2892 | STM2890 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.999 |
invJ | spaQ | STM2892 | STM2889 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | 0.946 |
sipB | invJ | STM2885 | STM2892 | Cell invasion protein; Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chape [...] | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | 0.984 |
sipB | spaO | STM2885 | STM2891 | Cell invasion protein; Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chape [...] | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.930 |
sipB | spaP | STM2885 | STM2890 | Cell invasion protein; Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chape [...] | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.861 |
sipB | spaQ | STM2885 | STM2889 | Cell invasion protein; Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chape [...] | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | 0.788 |
spaO | invJ | STM2891 | STM2892 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | 0.992 |
spaO | sipB | STM2891 | STM2885 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | Cell invasion protein; Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chape [...] | 0.930 |
spaO | spaP | STM2891 | STM2890 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.993 |
spaO | spaQ | STM2891 | STM2889 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | 0.988 |
spaP | invJ | STM2890 | STM2892 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | 0.999 |
spaP | sipB | STM2890 | STM2885 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | Cell invasion protein; Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chape [...] | 0.861 |
spaP | spaO | STM2890 | STM2891 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.993 |
spaP | spaQ | STM2890 | STM2889 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | 0.999 |
spaQ | invJ | STM2889 | STM2892 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the SpaN family. | 0.946 |
spaQ | sipB | STM2889 | STM2885 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | Cell invasion protein; Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chape [...] | 0.788 |
spaQ | spaO | STM2889 | STM2891 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.988 |
spaQ | spaP | STM2889 | STM2890 | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | Surface presentation of antigens; Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. | 0.999 |