STRINGSTRING
trxB trxB selD selD sufS sufS STM1498 STM1498 STM1499 STM1499 STM1557 STM1557 metG metG cysN cysN cysD cysD metC metC selA selA metE metE metB metB metH metH STM4446 STM4446
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
trxBSimilar to E. coli thioredoxin reductase (AAC73974.1); Blastp hit to AAC73974.1 (321 aa), 96% identity in aa 1 - 320. (322 aa)
selDSelenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (347 aa)
sufSSelenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. (406 aa)
STM1498Similar to E. coli putative oxidoreductase, major subunit (AAC74660.1); Blastp hit to AAC74660.1 (808 aa), 91% identity in aa 2 - 807; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (811 aa)
STM1499Putative dimethyl sulphoxide reductase, chain A1; Similar to E. coli putative oxidoreductase, major subunit (AAC74659.1); Blastp hit to AAC74659.1 (808 aa), 86% identity in aa 1 - 808; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (813 aa)
STM1557Putative aminotransferase; Similar to E. coli enzyme that may degrade or block biosynthesis of endogenous mal inducer, probably aminotrasferase (AAC74694.1); Blastp hit to AAC74694.1 (390 aa), 33% identity in aa 3 - 382. (400 aa)
metGMethionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (677 aa)
cysNATP-sulfurylase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (479 aa)
cysDATP-sulfurylase, subunit 1; Similar to E. coli ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2 (AAC75794.1); Blastp hit to AAC75794.1 (302 aa), 97% identity in aa 1 - 302. (302 aa)
metCCystathionine beta-lyase; Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. (395 aa)
selASelenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (463 aa)
metE5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (754 aa)
metBSimilar to E. coli cystathionine gamma-synthase (AAC76921.1); Blastp hit to AAC76921.1 (386 aa), 96% identity in aa 1 - 386. (386 aa)
metHB12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). (1256 aa)
STM4446Putative selenocysteine synthase; [L-seryl-tRNA(Ser) selenium transferase]. (372 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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