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icdA icdA gst gst zwf zwf gnd gnd yfcF yfcF pepB pepB gshA gshA gshB gshB speC speC gsp gsp ggt ggt gor gor STM4267 STM4267 ybgL ybgL pepA pepA speE speE pepD pepD ybdK ybdK speF speF ybgJ ybgJ ybgK ybgK yliJ yliJ pepN pepN btuE btuE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
icdAIsocitrate dehydrogenase in e14 prophage; Specific for NADP+; similar to E. coli isocitrate dehydrogenase, specific for NADP+ (AAC74220.1); Blastp hit to AAC74220.1 (416 aa), 96% identity in aa 1 - 416. (416 aa)
gstSimilar to E. coli glutathionine S-transferase (AAC74707.1); Blastp hit to AAC74707.1 (201 aa), 84% identity in aa 1 - 200. (201 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
gndGluconate-6-phosphate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
yfcFPutative glutathione-S-transferase; Similar to E. coli orf, hypothetical protein (AAC75361.1); Blastp hit to AAC75361.1 (214 aa), 80% identity in aa 1 - 214. (214 aa)
pepBPutative aminopeptidase; Probably plays an important role in intracellular peptide degradation; Belongs to the peptidase M17 family. (427 aa)
gshAGlutamate--cysteine ligase. (SW:GSH1_SALTY); Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (518 aa)
gshBSimilar to E. coli glutathione synthetase (AAC75984.1); Blastp hit to AAC75984.1 (316 aa), 90% identity in aa 1 - 313. (315 aa)
speCSimilar to E. coli ornithine decarboxylase isozyme (AAC76002.1); Blastp hit to AAC76002.1 (731 aa), 87% identity in aa 21 - 731. (711 aa)
gspBifunctional; similar to E. coli glutathionylspermidine synthetase/amidase (AAC76024.1); Blastp hit to AAC76024.1 (619 aa), 90% identity in aa 1 - 618; glutathionylspermidine amidase. (618 aa)
ggtSimilar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. (580 aa)
gorSimilar to E. coli glutathione oxidoreductase (AAC76525.1); Blastp hit to AAC76525.1 (450 aa), 94% identity in aa 1 - 450. (450 aa)
STM4267Putative glutathione S-transferase; Belongs to the GST superfamily. (222 aa)
ybgLPutative lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (244 aa)
pepAAminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (503 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (286 aa)
pepDSimilar to E. coli aminoacyl-histidine dipeptidase (peptidase D) (AAC73341.1); Blastp hit to AAC73341.1 (485 aa), 92% identity in aa 1 - 485. (485 aa)
ybdKPutative cytoplasmic protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity. (372 aa)
speFSimilar to E. coli ornithine decarboxylase isozyme, inducible (AAC73787.1); Blastp hit to AAC73787.1 (732 aa), 91% identity in aa 1 - 732. (732 aa)
ybgJSimilar to E. coli putative carboxylase (AAC73805.1); Blastp hit to AAC73805.1 (218 aa), 86% identity in aa 1 - 218. (218 aa)
ybgKSimilar to E. coli putative carboxylase (AAC73806.1); Blastp hit to AAC73806.1 (310 aa), 84% identity in aa 1 - 310. (310 aa)
yliJPutative glutathione S-transferase; Similar to E. coli putative transferase (AAC73925.1); Blastp hit to AAC73925.1 (210 aa), 82% identity in aa 3 - 210. (208 aa)
pepNSimilar to E. coli aminopeptidase N (AAC74018.1); Blastp hit to AAC74018.1 (870 aa), 94% identity in aa 1 - 870. (870 aa)
btuEVitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. (183 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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