STRINGSTRING
ppc ppc pfp pfp pgi pgi B1806_03495 B1806_03495 B1806_03320 B1806_03320 B1806_03310 B1806_03310 B1806_11595 B1806_11595 tpiA tpiA eno eno pgk pgk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppcUnannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (904 aa)
pfpUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (417 aa)
pgiUnannotated protein; Belongs to the GPI family. (764 aa)
B1806_03495Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
B1806_03320Unannotated protein; Belongs to the pyruvate kinase family. (490 aa)
B1806_03310Unannotated protein; Belongs to the class I fructose-bisphosphate aldolase family. (334 aa)
B1806_11595Unannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (345 aa)
tpiAUnannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (245 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (428 aa)
pgkUnannotated protein; Belongs to the phosphoglycerate kinase family. (392 aa)
Your Current Organism:
Metallibacterium scheffleri
NCBI taxonomy Id: 993689
Other names: DSM 24874, JCM 17596, M. scheffleri, Metallibacterium scheffleri Ziegler et al. 2013, gamma proteobacterium DKE, strain DKE6
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.