STRINGSTRING
aroC aroC nadA nadA B1806_07770 B1806_07770 B1806_07645 B1806_07645 dapF dapF aroQ aroQ aroE aroE B1806_01270 B1806_01270 B1806_01875 B1806_01875 ppc ppc B1806_05120 B1806_05120 hutI hutI B1806_10260 B1806_10260 GCA_002077135_01647 GCA_002077135_01647 B1806_10675 B1806_10675 dapD dapD hutU hutU dapA dapA B1806_05595 B1806_05595 GCA_002077135_02232 GCA_002077135_02232 aroA aroA asd asd dapB dapB B1806_12590 B1806_12590 aspA aspA B1806_12255 B1806_12255 B1806_00275 B1806_00275 kynU kynU B1806_08280 B1806_08280 B1806_14195 B1806_14195 mdh mdh aroK aroK aroB aroB B1806_10035 B1806_10035 dapE dapE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aroCUnannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (362 aa)
nadAUnannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (325 aa)
B1806_07770Unannotated protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1047 aa)
B1806_07645Unannotated protein. (761 aa)
dapFUnannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa)
aroQUnannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa)
aroEUnannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa)
B1806_01270Unannotated protein. (214 aa)
B1806_01875Unannotated protein. (124 aa)
ppcUnannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (904 aa)
B1806_05120Unannotated protein. (90 aa)
hutIUnannotated protein. (408 aa)
B1806_10260Unannotated protein; Belongs to the folylpolyglutamate synthase family. (436 aa)
GCA_002077135_01647Unannotated protein. (1574 aa)
B1806_10675Unannotated protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (868 aa)
dapDUnannotated protein; Belongs to the transferase hexapeptide repeat family. (274 aa)
hutUUnannotated protein; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (560 aa)
dapAUnannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa)
B1806_05595Unannotated protein. (164 aa)
GCA_002077135_02232Unannotated protein. (373 aa)
aroAUnannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (441 aa)
asdUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa)
dapBUnannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (271 aa)
B1806_12590Unannotated protein. (1634 aa)
aspAUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
B1806_12255Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (303 aa)
B1806_00275Unannotated protein. (628 aa)
kynUUnannotated protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (420 aa)
B1806_08280Unannotated protein; In the C-terminal section; belongs to the homoserine dehydrogenase family. (822 aa)
B1806_14195Unannotated protein. (89 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
aroKUnannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (186 aa)
aroBUnannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa)
B1806_10035Unannotated protein. (607 aa)
dapEUnannotated protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (377 aa)
Your Current Organism:
Metallibacterium scheffleri
NCBI taxonomy Id: 993689
Other names: DSM 24874, JCM 17596, M. scheffleri, Metallibacterium scheffleri Ziegler et al. 2013, gamma proteobacterium DKE, strain DKE6
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