STRINGSTRING
sucD sucD B1806_04475 B1806_04475 B1806_06315 B1806_06315 B1806_06545 B1806_06545 B1806_07650 B1806_07650 B1806_14945 B1806_14945 B1806_14935 B1806_14935 pckG pckG B1806_04640 B1806_04640 aspA aspA B1806_12485 B1806_12485 B1806_12480 B1806_12480 B1806_12475 B1806_12475 B1806_14195 B1806_14195 B1806_14200 B1806_14200 B1806_14205 B1806_14205 B1806_14210 B1806_14210 B1806_14215 B1806_14215 mdh mdh B1806_10025 B1806_10025 B1806_10030 B1806_10030 B1806_14725 B1806_14725 sucC sucC pdhA pdhA B1806_12115 B1806_12115 B1806_12110 B1806_12110 GCA_002077135_03423 GCA_002077135_03423
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
B1806_04475Unannotated protein. (287 aa)
B1806_06315Unannotated protein; Belongs to the citrate synthase family. (428 aa)
B1806_06545Unannotated protein. (442 aa)
B1806_07650Unannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (899 aa)
B1806_14945Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (442 aa)
B1806_14935Unannotated protein. (594 aa)
pckGUnannotated protein; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (593 aa)
B1806_04640Unannotated protein. (474 aa)
aspAUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
B1806_12485Unannotated protein. (943 aa)
B1806_12480Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (420 aa)
B1806_12475Unannotated protein. (474 aa)
B1806_14195Unannotated protein. (89 aa)
B1806_14200Unannotated protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (258 aa)
B1806_14205Unannotated protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (595 aa)
B1806_14210Unannotated protein. (127 aa)
B1806_14215Unannotated protein. (131 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
B1806_10025Unannotated protein. (351 aa)
B1806_10030Unannotated protein. (612 aa)
B1806_14725Unannotated protein. (341 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (360 aa)
B1806_12115Unannotated protein. (325 aa)
B1806_12110Unannotated protein. (465 aa)
GCA_002077135_03423Unannotated protein. (428 aa)
Your Current Organism:
Metallibacterium scheffleri
NCBI taxonomy Id: 993689
Other names: DSM 24874, JCM 17596, M. scheffleri, Metallibacterium scheffleri Ziegler et al. 2013, gamma proteobacterium DKE, strain DKE6
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