STRINGSTRING
PEX7 PEX7 W5NRD9_SHEEP W5NRD9_SHEEP ITIH4 ITIH4 W5NRN8_SHEEP W5NRN8_SHEEP MYOG MYOG W5NTE3_SHEEP W5NTE3_SHEEP H3-4 H3-4 NANOG NANOG KCTD19 KCTD19 PPP2R2B PPP2R2B W5P178_SHEEP W5P178_SHEEP TCP1 TCP1 LIN28A LIN28A EFNB2 EFNB2 FBXO17 FBXO17 W5P7G5_SHEEP W5P7G5_SHEEP W5P7I7_SHEEP W5P7I7_SHEEP PALM3 PALM3 W5P9Y2_SHEEP W5P9Y2_SHEEP KLF4 KLF4 MYC MYC MADCAM1 MADCAM1 LOC106990414 LOC106990414 W5PHI6_SHEEP W5PHI6_SHEEP POU5F1 POU5F1 MMS19 MMS19 PAX7 PAX7 PCSK4 PCSK4 W5PS91_SHEEP W5PS91_SHEEP W5PT25_SHEEP W5PT25_SHEEP MSH4 MSH4 W5PT85_SHEEP W5PT85_SHEEP FURIN FURIN LOC101115753 LOC101115753 DMRT1 DMRT1 SOX9 SOX9 ALB ALB AMH AMH MYF6 MYF6 MYF5 MYF5 SYCP3 SYCP3 PTPRC PTPRC MLH1 MLH1 YAE1 YAE1 SPO11 SPO11 TSPAN16 TSPAN16 REC8 REC8 W5QFP9_SHEEP W5QFP9_SHEEP HIST1H3A HIST1H3A SYCP1 SYCP1 PAX3 PAX3 HORMAD1 HORMAD1 MYOD1 MYOD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PEX7Peroxisomal biogenesis factor 7. (298 aa)
W5NRD9_SHEEPHistone domain-containing protein. (119 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (917 aa)
W5NRN8_SHEEPPOU-specific domain-containing protein. (298 aa)
MYOGBASIC domain-containing protein. (194 aa)
W5NTE3_SHEEPHistone H3; Belongs to the histone H3 family. (139 aa)
H3-4Histone H3; Belongs to the histone H3 family. (144 aa)
NANOGHomeobox domain-containing protein. (301 aa)
KCTD19Potassium channel tetramerization domain containing 19. (983 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (514 aa)
W5P178_SHEEPCCHC-type domain-containing protein. (203 aa)
TCP1T-complex 1. (558 aa)
LIN28ACCHC-type domain-containing protein. (204 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
FBXO17F-box protein 17. (161 aa)
W5P7G5_SHEEPUncharacterized protein. (284 aa)
W5P7I7_SHEEPUncharacterized protein. (302 aa)
PALM3Paralemmin 3. (731 aa)
W5P9Y2_SHEEPUncharacterized protein. (282 aa)
KLF4Uncharacterized protein. (340 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (423 aa)
MADCAM1Adhes-Ig_like domain-containing protein. (378 aa)
LOC106990414Histone H3; Belongs to the histone H3 family. (148 aa)
W5PHI6_SHEEPHistone H3; Belongs to the histone H3 family. (140 aa)
POU5F1POU domain protein. (360 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1053 aa)
PAX7Paired box 7. (501 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (701 aa)
W5PS91_SHEEPHistone H3; Belongs to the histone H3 family. (140 aa)
W5PT25_SHEEPPOU domain protein. (358 aa)
MSH4MutS homolog 4. (935 aa)
W5PT85_SHEEPUncharacterized protein. (343 aa)
FURINP/Homo B domain-containing protein; Belongs to the peptidase S8 family. (712 aa)
LOC101115753Histone H3; Belongs to the histone H3 family. (136 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (332 aa)
SOX9SRY-box transcription factor 9. (383 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (609 aa)
AMHAMH_N domain-containing protein. (213 aa)
MYF6Myogenic factor 6. (242 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
SYCP3Synaptonemal complex protein 3. (225 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1235 aa)
MLH1MutL homolog 1. (758 aa)
YAE1YAE1 maturation factor of ABCE1. (226 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (395 aa)
TSPAN16Tetraspanin 16; Belongs to the tetraspanin (TM4SF) family. (245 aa)
REC8REC8 meiotic recombination protein. (592 aa)
W5QFP9_SHEEPHistone H3; Belongs to the histone H3 family. (139 aa)
HIST1H3AHistone H3; Belongs to the histone H3 family. (139 aa)
SYCP1Synaptonemal complex protein 1. (1000 aa)
PAX3Paired box 3. (508 aa)
HORMAD1HORMA domain containing 1. (393 aa)
MYOD1Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (198 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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