(29 nodes) Mitochondrial protein import, and Tubulin/FtsZ family, GTPase domain network (Ovis aries)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	TIMM17A	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (172 aa)
	W5NSC6_SHEEP	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (97 aa)
	CHCHD4	Coiled-coil-helix-coiled-coil-helix domain containing 4. (140 aa)
	TIMM8A	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (97 aa)
	GPR157	G_PROTEIN_RECEP_F2_4 domain-containing protein. (212 aa)
	W5NV07_SHEEP	Uncharacterized protein. (36 aa)
	LOC101118849	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (209 aa)
	TIMM44	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (451 aa)
	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3. (535 aa)
	W5P0F0_SHEEP	Uncharacterized protein. (160 aa)
	W5P1I3_SHEEP	J domain-containing protein. (116 aa)
	ENSOARP00000004282	annotation not available (116 aa)
	MSTO1	Misato mitochondrial distribution and morphology regulator 1. (572 aa)
	TIMM21	Translocase of inner mitochondrial membrane 21. (244 aa)
	GRPEL2	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (232 aa)
	SLC25A22	Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
	TIMM50	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (360 aa)
	C3orf18	Chromosome 3 open reading frame 18. (162 aa)
	W5PJK2_SHEEP	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (330 aa)
	TIMM10	Translocase of inner mitochondrial membrane 10. (90 aa)
	W5PM68_SHEEP	Uncharacterized protein. (469 aa)
	TIMM22	Translocase of inner mitochondrial membrane 22. (196 aa)
	TIMM17B	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (172 aa)
	CISD2	CDGSH iron sulfur domain 2. (102 aa)
	W5Q1T7_SHEEP	Uncharacterized protein. (185 aa)
	HSPA9	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
	GFER	Sulfhydryl oxidase. (327 aa)
	TIMM10B	zf-Tim10_DDP domain-containing protein. (116 aa)
	TIMM9	Translocase of inner mitochondrial membrane 9. (89 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3orf18	GRPEL2	ENSOARP00000009525	ENSOARP00000005622	Chromosome 3 open reading frame 18.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.459
C3orf18	HSPA9	ENSOARP00000009525	ENSOARP00000017758	Chromosome 3 open reading frame 18.	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	0.701
C3orf18	LOC101118849	ENSOARP00000009525	ENSOARP00000002512	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.692
C3orf18	TIMM10	ENSOARP00000009525	ENSOARP00000010649	Chromosome 3 open reading frame 18.	Translocase of inner mitochondrial membrane 10.	0.461
C3orf18	TIMM17A	ENSOARP00000009525	ENSOARP00000000228	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.459
C3orf18	TIMM17B	ENSOARP00000009525	ENSOARP00000012446	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.459
C3orf18	TIMM21	ENSOARP00000009525	ENSOARP00000005053	Chromosome 3 open reading frame 18.	Translocase of inner mitochondrial membrane 21.	0.508
C3orf18	TIMM44	ENSOARP00000009525	ENSOARP00000003307	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.668
C3orf18	TIMM50	ENSOARP00000009525	ENSOARP00000006668	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.486
C3orf18	TIMM9	ENSOARP00000009525	ENSOARP00000022688	Chromosome 3 open reading frame 18.	Translocase of inner mitochondrial membrane 9.	0.447
C3orf18	W5P0F0_SHEEP	ENSOARP00000009525	ENSOARP00000003898	Chromosome 3 open reading frame 18.	Uncharacterized protein.	0.459
CHCHD4	GFER	ENSOARP00000001273	ENSOARP00000018417	Coiled-coil-helix-coiled-coil-helix domain containing 4.	Sulfhydryl oxidase.	0.952
CHCHD4	LOC101118849	ENSOARP00000001273	ENSOARP00000002512	Coiled-coil-helix-coiled-coil-helix domain containing 4.	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.408
CHCHD4	TIMM10	ENSOARP00000001273	ENSOARP00000010649	Coiled-coil-helix-coiled-coil-helix domain containing 4.	Translocase of inner mitochondrial membrane 10.	0.842
CHCHD4	TIMM10B	ENSOARP00000001273	ENSOARP00000019468	Coiled-coil-helix-coiled-coil-helix domain containing 4.	zf-Tim10_DDP domain-containing protein.	0.741
CHCHD4	TIMM21	ENSOARP00000001273	ENSOARP00000005053	Coiled-coil-helix-coiled-coil-helix domain containing 4.	Translocase of inner mitochondrial membrane 21.	0.476
CHCHD4	TIMM22	ENSOARP00000001273	ENSOARP00000011966	Coiled-coil-helix-coiled-coil-helix domain containing 4.	Translocase of inner mitochondrial membrane 22.	0.539
CHCHD4	TIMM50	ENSOARP00000001273	ENSOARP00000006668	Coiled-coil-helix-coiled-coil-helix domain containing 4.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.514
CHCHD4	TIMM8A	ENSOARP00000001273	ENSOARP00000001687	Coiled-coil-helix-coiled-coil-helix domain containing 4.	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family.	0.678
CHCHD4	TIMM9	ENSOARP00000001273	ENSOARP00000022688	Coiled-coil-helix-coiled-coil-helix domain containing 4.	Translocase of inner mitochondrial membrane 9.	0.866