5 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MRTFB	Myocardin related transcription factor B. (1044 aa)
	CDC14B	Uncharacterized protein. (461 aa)
	W5PN72_SHEEP	Protein kinase domain-containing protein. (345 aa)
	STK38	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (466 aa)
	CDC14A	Cell division cycle 14A. (568 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC14A	STK38	ENSOARP00000019523	ENSOARP00000014472	Cell division cycle 14A.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.641
CDC14A	W5PN72_SHEEP	ENSOARP00000019523	ENSOARP00000011898	Cell division cycle 14A.	Protein kinase domain-containing protein.	0.641
CDC14B	STK38	ENSOARP00000009062	ENSOARP00000014472	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.641
CDC14B	W5PN72_SHEEP	ENSOARP00000009062	ENSOARP00000011898	Uncharacterized protein.	Protein kinase domain-containing protein.	0.641
STK38	CDC14A	ENSOARP00000014472	ENSOARP00000019523	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cell division cycle 14A.	0.641
STK38	CDC14B	ENSOARP00000014472	ENSOARP00000009062	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.641
W5PN72_SHEEP	CDC14A	ENSOARP00000011898	ENSOARP00000019523	Protein kinase domain-containing protein.	Cell division cycle 14A.	0.641
W5PN72_SHEEP	CDC14B	ENSOARP00000011898	ENSOARP00000009062	Protein kinase domain-containing protein.	Uncharacterized protein.	0.641