(5 nodes) Mixed, incl. Collagen V binding, and EF hand network (Ovis aries)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSPB3	Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family. (149 aa)
	ERF	ETS2 repressor factor. (510 aa)
	ECM2	Extracellular matrix protein 2. (703 aa)
	DPT	Dermatopontin. (201 aa)
	W5PZ73_SHEEP	EF-hand domain-containing protein. (169 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DPT	ECM2	ENSOARP00000009905	ENSOARP00000008834	Dermatopontin.	Extracellular matrix protein 2.	0.784
ECM2	DPT	ENSOARP00000008834	ENSOARP00000009905	Extracellular matrix protein 2.	Dermatopontin.	0.784
ECM2	ERF	ENSOARP00000008834	ENSOARP00000008606	Extracellular matrix protein 2.	ETS2 repressor factor.	0.713
ECM2	HSPB3	ENSOARP00000008834	ENSOARP00000005996	Extracellular matrix protein 2.	Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family.	0.522
ECM2	W5PZ73_SHEEP	ENSOARP00000008834	ENSOARP00000015759	Extracellular matrix protein 2.	EF-hand domain-containing protein.	0.558
ERF	ECM2	ENSOARP00000008606	ENSOARP00000008834	ETS2 repressor factor.	Extracellular matrix protein 2.	0.713
ERF	HSPB3	ENSOARP00000008606	ENSOARP00000005996	ETS2 repressor factor.	Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family.	0.913
ERF	W5PZ73_SHEEP	ENSOARP00000008606	ENSOARP00000015759	ETS2 repressor factor.	EF-hand domain-containing protein.	0.612
HSPB3	ECM2	ENSOARP00000005996	ENSOARP00000008834	Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family.	Extracellular matrix protein 2.	0.522
HSPB3	ERF	ENSOARP00000005996	ENSOARP00000008606	Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family.	ETS2 repressor factor.	0.913
HSPB3	W5PZ73_SHEEP	ENSOARP00000005996	ENSOARP00000015759	Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family.	EF-hand domain-containing protein.	0.579
W5PZ73_SHEEP	ECM2	ENSOARP00000015759	ENSOARP00000008834	EF-hand domain-containing protein.	Extracellular matrix protein 2.	0.558
W5PZ73_SHEEP	ERF	ENSOARP00000015759	ENSOARP00000008606	EF-hand domain-containing protein.	ETS2 repressor factor.	0.612
W5PZ73_SHEEP	HSPB3	ENSOARP00000015759	ENSOARP00000005996	EF-hand domain-containing protein.	Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family.	0.579