135 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TEX15	Testis expressed 15, meiosis and synapsis associated. (3179 aa)
	W5NQ37_SHEEP	Uncharacterized protein. (489 aa)
	WAPL	WAPL cohesin release factor. (1237 aa)
	TMEM183A	Transmembrane protein 183A. (376 aa)
	W5NRM1_SHEEP	MAGE domain-containing protein. (324 aa)
	TMEM229B	Transmembrane protein 229B. (168 aa)
	W5NSU4_SHEEP	MAGE domain-containing protein. (263 aa)
	W5NSV6_SHEEP	MAGE domain-containing protein. (273 aa)
	W5NT07_SHEEP	MAGE domain-containing protein. (264 aa)
	W5NT12_SHEEP	MAGE domain-containing protein. (367 aa)
	W5NU37_SHEEP	MAGE domain-containing protein. (254 aa)
	W5NU45_SHEEP	MAGE domain-containing protein. (253 aa)
	PLD6	Phospholipase D family member 6. (220 aa)
	TERB1	Telomere repeat binding bouquet formation protein 1. (732 aa)
	MAGEF1	MAGE family member F1. (307 aa)
	PSMC3IP	PSMC3 interacting protein. (217 aa)
	MND1	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (204 aa)
	CTCF	CCCTC-binding factor. (730 aa)
	W5P0X3_SHEEP	Uncharacterized protein. (260 aa)
	W5P170_SHEEP	MAGE domain-containing protein. (282 aa)
	W5P1C6_SHEEP	Uncharacterized protein. (332 aa)
	PNLDC1	PARN like, ribonuclease domain containing 1. (530 aa)
	TMEM106A	Transmembrane protein 106A. (261 aa)
	GTSF1L	Gametocyte specific factor 1 like. (156 aa)
	RASGRP4	RAS guanyl releasing protein 4. (673 aa)
	W5P7R1_SHEEP	MAGE domain-containing protein. (151 aa)
	PODN	Podocan. (657 aa)
	MAGED2	MAGE family member D2. (579 aa)
	NSMCE4A	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (299 aa)
	HORMAD2	HORMA domain containing 2. (308 aa)
	LOC101105393	MAGE domain-containing protein. (320 aa)
	SHOC1	Shortage in chiasmata 1. (1511 aa)
	TDRD9	Tudor domain containing 9. (1344 aa)
	MEI4	Meiotic double-stranded break formation protein 4. (395 aa)
	W5PBY6_SHEEP	MAGE domain-containing protein. (237 aa)
	STAG1	Stromal antigen 1. (1258 aa)
	MAD2L1BP	MAD2L1 binding protein. (274 aa)
	NSMCE2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (277 aa)
	MAU2	MAU2 sister chromatid cohesion factor. (622 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	W5PH48_SHEEP	MAGE domain-containing protein. (256 aa)
	W5PH65_SHEEP	MAGE domain-containing protein. (289 aa)
	W5PHG8_SHEEP	MAGE domain-containing protein. (198 aa)
	W5PHM5_SHEEP	Uncharacterized protein. (411 aa)
	W5PHR8_SHEEP	Uncharacterized protein. (430 aa)
	W5PHS1_SHEEP	MAGE domain-containing protein. (425 aa)
	LOC114111334	MAGE domain-containing protein. (261 aa)
	LOC105605704	MAGE domain-containing protein. (262 aa)
	W5PHW9_SHEEP	MAGE domain-containing protein. (236 aa)
	W5PI79_SHEEP	MAGE domain-containing protein. (342 aa)
	PIWIL4	Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family. (854 aa)
	SMC3	Structural maintenance of chromosomes protein. (1217 aa)
	SYCE2	Synaptonemal complex central element protein 2. (184 aa)
	PIWIL2	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (973 aa)
	RAD21	RAD21 cohesin complex component. (630 aa)
	ANKRD34B	Ankyrin repeat domain 34B. (512 aa)
	LOC101107506	MAGE domain-containing protein. (343 aa)
	LOC101102215	MAGE domain-containing protein. (337 aa)
	NIPBL	Nipped-B protein. (2804 aa)
	TDRD6	Tudor domain containing 6. (2015 aa)
	PDS5B	PDS5 cohesin associated factor B. (1449 aa)
	STK31	Serine/threonine kinase 31. (1019 aa)
	HSF2BP	Heat shock transcription factor 2 binding protein. (334 aa)
	MAJIN	Membrane anchored junction protein. (257 aa)
	DDX11	DEAD/H-box helicase 11. (903 aa)
	W5PQH6_SHEEP	S1-like domain-containing protein. (241 aa)
	MAEL	Maelstrom spermatogenic transposon silencer. (437 aa)
	W5PQY7_SHEEP	Uncharacterized protein. (393 aa)
	PDS5A	PDS5 cohesin associated factor A. (1337 aa)
	W5PRT8_SHEEP	Stathmin; Belongs to the stathmin family. (149 aa)
	TC2N	Tandem C2 domains, nuclear. (490 aa)
	W5PSN6_SHEEP	Uncharacterized protein. (156 aa)
	SMC5	SMC_N domain-containing protein. (1167 aa)
	W5PTV0_SHEEP	Tudor domain-containing protein. (116 aa)
	W5PUA0_SHEEP	MAGE domain-containing protein. (191 aa)
	SYCE1	Synaptonemal complex central element protein 1. (323 aa)
	SCML2	Scm polycomb group protein like 2. (704 aa)
	STAG2	Stromal antigen 2. (1233 aa)
	TDRD1	Uncharacterized protein. (1197 aa)
	MOB3A	MOB kinase activator 3A. (217 aa)
	FAM151B	Family with sequence similarity 151 member B. (276 aa)
	ESCO2	Establishment of sister chromatid cohesion N-acetyltransferase 2. (734 aa)
	SLC16A12	Solute carrier family 16 member 12. (486 aa)
	SYCP3	Synaptonemal complex protein 3. (225 aa)
	BOLL	Boule homolog, RNA binding protein. (295 aa)
	ZGLP1	Zinc finger GATA like protein 1. (270 aa)
	HFM1	Helicase for meiosis 1. (1434 aa)
	TEX11	Testis expressed 11. (920 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (409 aa)
	GTSF1	Gametocyte specific factor 1. (167 aa)
	TRBV19	T cell receptor beta variable 19. (127 aa)
	PIWIL1	Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (935 aa)
	SMC6	Structural maintenance of chromosomes 6. (1101 aa)
	MEIOB	Uncharacterized protein. (202 aa)
	ANKRD31	ANK_REP_REGION domain-containing protein. (1276 aa)
	SPATA22	Spermatogenesis associated 22. (326 aa)
	ZFX	Uncharacterized protein. (800 aa)
	STAG3	Stromal antigen 3. (1275 aa)
	TDRD5	Tudor domain containing 5. (1039 aa)
	W5Q855_SHEEP	MAGE domain-containing protein. (304 aa)
	LOC101108036	MAGE domain-containing protein. (262 aa)
	LOC114111425	MAGE domain-containing protein. (345 aa)
	MCMDC2	Minichromosome maintenance domain containing 2. (681 aa)
	W5Q948_SHEEP	MAGE domain-containing protein. (279 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (395 aa)
	MAGEB1	MAGE domain-containing protein. (419 aa)
	SWSAP1	SWIM-type zinc finger 7 associated protein 1. (250 aa)
	LOC101111610	MAGE domain-containing protein. (347 aa)
	W5QAF6_SHEEP	MAGE domain-containing protein. (345 aa)
	PIWIL3	Piwi like RNA-mediated gene silencing 3; Belongs to the argonaute family. (875 aa)
	MEI1	Meiotic double-stranded break formation protein 1. (1261 aa)
	LOC101107262	MAGE domain-containing protein. (347 aa)
	W5QBH0_SHEEP	MAGE domain-containing protein. (355 aa)
	W5QBI5_SHEEP	MAGE domain-containing protein. (379 aa)
	W5QBM1_SHEEP	MAGE domain-containing protein. (324 aa)
	LOC101121660	MAGE domain-containing protein. (333 aa)
	RAD21L1	RAD21 cohesin complex component like 1. (554 aa)
	NSMCE1	NSE1 homolog, SMC5-SMC6 complex component. (263 aa)
	W5QBY4_SHEEP	MAGE domain-containing protein. (150 aa)
	W5QC40_SHEEP	MAGE domain-containing protein. (344 aa)
	HENMT1	HEN methyltransferase 1. (382 aa)
	ASZ1	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...] (493 aa)
	REC114	REC114 meiotic recombination protein. (214 aa)
	W5QCI2_SHEEP	MAGE domain-containing protein. (338 aa)
	REC8	REC8 meiotic recombination protein. (592 aa)
	RNF212B	Ring finger protein 212B. (300 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1235 aa)
	MOV10L1	Mov10 like RISC complex RNA helicase 1. (1217 aa)
	GMCL1	BTB domain-containing protein. (529 aa)
	SYCE3	Synaptonemal complex central element protein 3. (87 aa)
	SYCP1	Synaptonemal complex protein 1. (1000 aa)
	HORMAD1	HORMA domain containing 1. (393 aa)
	TDRKH	Tudor and KH domain containing. (560 aa)
	TBPL2	TATA-box binding protein like 2. (378 aa)
	PCNX1	Pecanex 1. (2292 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD31	HORMAD1	ENSOARP00000017933	ENSOARP00000022408	ANK_REP_REGION domain-containing protein.	HORMA domain containing 1.	0.515
ANKRD31	HORMAD2	ENSOARP00000017933	ENSOARP00000006608	ANK_REP_REGION domain-containing protein.	HORMA domain containing 2.	0.482
ANKRD31	MAJIN	ENSOARP00000017933	ENSOARP00000012121	ANK_REP_REGION domain-containing protein.	Membrane anchored junction protein.	0.530
ANKRD31	MEI1	ENSOARP00000017933	ENSOARP00000019932	ANK_REP_REGION domain-containing protein.	Meiotic double-stranded break formation protein 1.	0.831
ANKRD31	MEI4	ENSOARP00000017933	ENSOARP00000007256	ANK_REP_REGION domain-containing protein.	Meiotic double-stranded break formation protein 4.	0.536
ANKRD31	MEIOB	ENSOARP00000017933	ENSOARP00000017923	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.430
ANKRD31	MND1	ENSOARP00000017933	ENSOARP00000003191	ANK_REP_REGION domain-containing protein.	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.	0.477
ANKRD31	REC114	ENSOARP00000017933	ENSOARP00000020419	ANK_REP_REGION domain-containing protein.	REC114 meiotic recombination protein.	0.959
ANKRD31	REC8	ENSOARP00000017933	ENSOARP00000020623	ANK_REP_REGION domain-containing protein.	REC8 meiotic recombination protein.	0.428
ANKRD31	SPO11	ENSOARP00000017933	ENSOARP00000019324	ANK_REP_REGION domain-containing protein.	SPO11 initiator of meiotic double stranded breaks.	0.527
ANKRD31	STAG3	ENSOARP00000017933	ENSOARP00000018490	ANK_REP_REGION domain-containing protein.	Stromal antigen 3.	0.419
ANKRD31	SYCE1	ENSOARP00000017933	ENSOARP00000014418	ANK_REP_REGION domain-containing protein.	Synaptonemal complex central element protein 1.	0.628
ANKRD31	SYCE2	ENSOARP00000017933	ENSOARP00000010843	ANK_REP_REGION domain-containing protein.	Synaptonemal complex central element protein 2.	0.442
ANKRD31	SYCP1	ENSOARP00000017933	ENSOARP00000021568	ANK_REP_REGION domain-containing protein.	Synaptonemal complex protein 1.	0.664
ANKRD31	SYCP3	ENSOARP00000017933	ENSOARP00000016365	ANK_REP_REGION domain-containing protein.	Synaptonemal complex protein 3.	0.513
ANKRD31	W5NQ37_SHEEP	ENSOARP00000017933	ENSOARP00000000277	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.470
ANKRD31	W5P0X3_SHEEP	ENSOARP00000017933	ENSOARP00000004072	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.470
ANKRD31	W5P1C6_SHEEP	ENSOARP00000017933	ENSOARP00000004225	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.470
ANKRD34B	FAM151B	ENSOARP00000011116	ENSOARP00000015868	Ankyrin repeat domain 34B.	Family with sequence similarity 151 member B.	0.457
ASZ1	BOLL	ENSOARP00000020381	ENSOARP00000016781	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...]	Boule homolog, RNA binding protein.	0.758