17 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WAPL	WAPL cohesin release factor. (1237 aa)
	STAG1	Stromal antigen 1. (1258 aa)
	MAU2	MAU2 sister chromatid cohesion factor. (622 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	SMC3	Structural maintenance of chromosomes protein. (1217 aa)
	RAD21	RAD21 cohesin complex component. (630 aa)
	NIPBL	Nipped-B protein. (2804 aa)
	PDS5B	PDS5 cohesin associated factor B. (1449 aa)
	DDX11	DEAD/H-box helicase 11. (903 aa)
	W5PQY7_SHEEP	Uncharacterized protein. (393 aa)
	PDS5A	PDS5 cohesin associated factor A. (1337 aa)
	STAG2	Stromal antigen 2. (1233 aa)
	ESCO2	Establishment of sister chromatid cohesion N-acetyltransferase 2. (734 aa)
	STAG3	Stromal antigen 3. (1275 aa)
	RAD21L1	RAD21 cohesin complex component like 1. (554 aa)
	REC8	REC8 meiotic recombination protein. (592 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1235 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX11	ESCO2	ENSOARP00000012282	ENSOARP00000015925	DEAD/H-box helicase 11.	Establishment of sister chromatid cohesion N-acetyltransferase 2.	0.830
DDX11	NIPBL	ENSOARP00000012282	ENSOARP00000011369	DEAD/H-box helicase 11.	Nipped-B protein.	0.816
DDX11	PDS5A	ENSOARP00000012282	ENSOARP00000013105	DEAD/H-box helicase 11.	PDS5 cohesin associated factor A.	0.602
DDX11	RAD21	ENSOARP00000012282	ENSOARP00000011111	DEAD/H-box helicase 11.	RAD21 cohesin complex component.	0.780
DDX11	RAD21L1	ENSOARP00000012282	ENSOARP00000020132	DEAD/H-box helicase 11.	RAD21 cohesin complex component like 1.	0.485
DDX11	SMC1A	ENSOARP00000012282	ENSOARP00000009210	DEAD/H-box helicase 11.	Structural maintenance of chromosomes protein.	0.634
DDX11	SMC3	ENSOARP00000012282	ENSOARP00000010465	DEAD/H-box helicase 11.	Structural maintenance of chromosomes protein.	0.687
DDX11	WAPL	ENSOARP00000012282	ENSOARP00000000467	DEAD/H-box helicase 11.	WAPL cohesin release factor.	0.477
ESCO2	DDX11	ENSOARP00000015925	ENSOARP00000012282	Establishment of sister chromatid cohesion N-acetyltransferase 2.	DEAD/H-box helicase 11.	0.830
ESCO2	MAU2	ENSOARP00000015925	ENSOARP00000009028	Establishment of sister chromatid cohesion N-acetyltransferase 2.	MAU2 sister chromatid cohesion factor.	0.771
ESCO2	NIPBL	ENSOARP00000015925	ENSOARP00000011369	Establishment of sister chromatid cohesion N-acetyltransferase 2.	Nipped-B protein.	0.811
ESCO2	PDS5A	ENSOARP00000015925	ENSOARP00000013105	Establishment of sister chromatid cohesion N-acetyltransferase 2.	PDS5 cohesin associated factor A.	0.899
ESCO2	PDS5B	ENSOARP00000015925	ENSOARP00000011715	Establishment of sister chromatid cohesion N-acetyltransferase 2.	PDS5 cohesin associated factor B.	0.937
ESCO2	RAD21	ENSOARP00000015925	ENSOARP00000011111	Establishment of sister chromatid cohesion N-acetyltransferase 2.	RAD21 cohesin complex component.	0.955
ESCO2	RAD21L1	ENSOARP00000015925	ENSOARP00000020132	Establishment of sister chromatid cohesion N-acetyltransferase 2.	RAD21 cohesin complex component like 1.	0.752
ESCO2	REC8	ENSOARP00000015925	ENSOARP00000020623	Establishment of sister chromatid cohesion N-acetyltransferase 2.	REC8 meiotic recombination protein.	0.795
ESCO2	SMC1A	ENSOARP00000015925	ENSOARP00000009210	Establishment of sister chromatid cohesion N-acetyltransferase 2.	Structural maintenance of chromosomes protein.	0.879
ESCO2	SMC1B	ENSOARP00000015925	ENSOARP00000020828	Establishment of sister chromatid cohesion N-acetyltransferase 2.	Structural maintenance of chromosomes protein.	0.868
ESCO2	SMC3	ENSOARP00000015925	ENSOARP00000010465	Establishment of sister chromatid cohesion N-acetyltransferase 2.	Structural maintenance of chromosomes protein.	0.977
ESCO2	STAG1	ENSOARP00000015925	ENSOARP00000008447	Establishment of sister chromatid cohesion N-acetyltransferase 2.	Stromal antigen 1.	0.620