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PKLR PKLR PGAM1 PGAM1 ENO2 ENO2 TPI1 TPI1 ENO3 ENO3 BPGM BPGM GAPDH GAPDH PGK2 PGK2 ENO1 ENO1 W5PK04_SHEEP W5PK04_SHEEP PGAM2 PGAM2 PFKP PFKP W5PYK2_SHEEP W5PYK2_SHEEP PCK1 PCK1 ENO4 ENO4 PGK1 PGK1 PARP6 PARP6 PCK2 PCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (593 aa)
PGAM1Uncharacterized protein. (208 aa)
ENO2Enolase 2. (434 aa)
TPI1Triosephosphate isomerase. (214 aa)
ENO3Enolase 3. (434 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (334 aa)
PGK2Phosphoglycerate kinase. (417 aa)
ENO1Enolase 1. (452 aa)
W5PK04_SHEEPPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (200 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (256 aa)
PFKP6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (790 aa)
W5PYK2_SHEEPEnolase_C domain-containing protein. (317 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (620 aa)
ENO4Enolase 4. (613 aa)
PGK1Phosphoglycerate kinase. (420 aa)
PARP6Poly [ADP-ribose] polymerase. (610 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (724 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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