18 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OTC	Ornithine carbamoyltransferase, mitochondrial. (355 aa)
	ASL	Uncharacterized protein. (468 aa)
	GLUD1	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (522 aa)
	GAD1	Glutamate decarboxylase 1. (599 aa)
	ASNS	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	GAD2	Glutamate decarboxylase 2. (578 aa)
	W5P775_SHEEP	Uncharacterized protein. (543 aa)
	ALDH18A1	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)
	NAGS	N-acetylglutamate synthase. (525 aa)
	ASS1	Argininosuccinate synthase 1. (410 aa)
	GLS2	Glutaminase 2. (602 aa)
	GLS	Glutaminase. (634 aa)
	ASRGL1	Asparaginase and isoaspartyl peptidase 1. (312 aa)
	ALDH7A1	Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (539 aa)
	AASS	Aminoadipate-semialdehyde synthase. (926 aa)
	GLUL	Glutamine synthetase. (373 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1500 aa)
	CAD	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2223 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AASS	ALDH18A1	ENSOARP00000019953	ENSOARP00000006765	Aminoadipate-semialdehyde synthase.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.584
AASS	ALDH7A1	ENSOARP00000019953	ENSOARP00000019693	Aminoadipate-semialdehyde synthase.	Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.	0.957
AASS	ASL	ENSOARP00000019953	ENSOARP00000000699	Aminoadipate-semialdehyde synthase.	Uncharacterized protein.	0.540
AASS	ASS1	ENSOARP00000019953	ENSOARP00000008253	Aminoadipate-semialdehyde synthase.	Argininosuccinate synthase 1.	0.487
AASS	CPS1	ENSOARP00000019953	ENSOARP00000020635	Aminoadipate-semialdehyde synthase.	Carbamoyl-phosphate synthase 1.	0.487
AASS	GLS2	ENSOARP00000019953	ENSOARP00000009289	Aminoadipate-semialdehyde synthase.	Glutaminase 2.	0.487
ALDH18A1	AASS	ENSOARP00000006765	ENSOARP00000019953	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Aminoadipate-semialdehyde synthase.	0.584
ALDH18A1	ALDH7A1	ENSOARP00000006765	ENSOARP00000019693	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.	0.850
ALDH18A1	ASL	ENSOARP00000006765	ENSOARP00000000699	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Uncharacterized protein.	0.773
ALDH18A1	ASNS	ENSOARP00000006765	ENSOARP00000005016	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Asparagine synthetase [glutamine-hydrolyzing].	0.931
ALDH18A1	ASS1	ENSOARP00000006765	ENSOARP00000008253	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Argininosuccinate synthase 1.	0.796
ALDH18A1	CAD	ENSOARP00000006765	ENSOARP00000020648	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.814
ALDH18A1	CPS1	ENSOARP00000006765	ENSOARP00000020635	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Carbamoyl-phosphate synthase 1.	0.814
ALDH18A1	GAD1	ENSOARP00000006765	ENSOARP00000002472	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamate decarboxylase 1.	0.858
ALDH18A1	GAD2	ENSOARP00000006765	ENSOARP00000005214	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamate decarboxylase 2.	0.858
ALDH18A1	GLS	ENSOARP00000006765	ENSOARP00000014816	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutaminase.	0.853
ALDH18A1	GLS2	ENSOARP00000006765	ENSOARP00000009289	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutaminase 2.	0.972
ALDH18A1	GLUD1	ENSOARP00000006765	ENSOARP00000000794	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.984
ALDH18A1	GLUL	ENSOARP00000006765	ENSOARP00000020145	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamine synthetase.	0.920
ALDH18A1	NAGS	ENSOARP00000006765	ENSOARP00000006942	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	N-acetylglutamate synthase.	0.756