43 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPAG8	Sperm associated antigen 8. (493 aa)
	ACTRT3	Actin related protein T3; Belongs to the actin family. (368 aa)
	HSPA2	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (636 aa)
	MLH3	MutL homolog 3. (1485 aa)
	CTCF	CCCTC-binding factor. (730 aa)
	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1042 aa)
	TERF2	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (502 aa)
	STPG4	Sperm-tail PG-rich repeat containing 4. (232 aa)
	CDK7	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (354 aa)
	CELF1	CUGBP Elav-like family member 1. (517 aa)
	TERF2IP	TERF2 interacting protein. (367 aa)
	ZMYND15	Zinc finger MYND-type containing 15. (777 aa)
	ANKRD37	Ankyrin repeat domain 37. (158 aa)
	STRA8	Stimulated by retinoic acid 8. (366 aa)
	TOPBP1	DNA topoisomerase II binding protein 1. (1524 aa)
	PATZ1	POZ/BTB and AT hook containing zinc finger 1. (628 aa)
	TRIM24	Tripartite motif containing 24. (934 aa)
	CDK2	Protein kinase domain-containing protein. (298 aa)
	DAZAP1	DAZ associated protein 1. (401 aa)
	AIRE	Autoimmune regulator. (440 aa)
	MAEL	Maelstrom spermatogenic transposon silencer. (437 aa)
	LIMK1	LIM domain kinase 1. (624 aa)
	TCFL5	Transcription factor like 5. (346 aa)
	ANKRD17	Ankyrin repeat domain 17. (2466 aa)
	TAF3	TATA-box binding protein associated factor 3. (794 aa)
	TOP2A	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1546 aa)
	TBPL1	TATA-box binding protein like 1. (188 aa)
	TAF4	TATA-box binding protein associated factor 4. (770 aa)
	ZFPM2	Zinc finger protein, FOG family member 2. (1142 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (409 aa)
	TESMIN	Testis expressed metallothionein like protein. (536 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (267 aa)
	TAF10	TATA-box binding protein associated factor 10. (195 aa)
	SPATA24	Spermatogenesis associated 24. (205 aa)
	STAG3	Stromal antigen 3. (1275 aa)
	TERF2IP-2	Telomeric repeat-binding factor 2-interacting protein 1. (44 aa)
	LOC101121602	ANK_REP_REGION domain-containing protein. (2585 aa)
	MORC1	MORC family CW-type zinc finger 1. (985 aa)
	REC8	REC8 meiotic recombination protein. (592 aa)
	SYCP1	Synaptonemal complex protein 1. (1000 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	SCMH1	Scm polycomb group protein homolog 1. (654 aa)
	KDM3A	Lysine demethylase 3A. (1319 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTRT3	TBPL1	ENSOARP00000000829	ENSOARP00000015709	Actin related protein T3; Belongs to the actin family.	TATA-box binding protein like 1.	0.409
AIRE	PCNA	ENSOARP00000012667	ENSOARP00000018385	Autoimmune regulator.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.475
ANKRD37	KDM3A	ENSOARP00000008375	ENSOARP00000022208	Ankyrin repeat domain 37.	Lysine demethylase 3A.	0.480
CDK2	CDK7	ENSOARP00000011447	ENSOARP00000006130	Protein kinase domain-containing protein.	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	0.981
CDK2	MLH3	ENSOARP00000011447	ENSOARP00000001705	Protein kinase domain-containing protein.	MutL homolog 3.	0.432
CDK2	PCNA	ENSOARP00000011447	ENSOARP00000018385	Protein kinase domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.831
CDK2	RAD51	ENSOARP00000011447	ENSOARP00000021748	Protein kinase domain-containing protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.526
CDK2	SYCP1	ENSOARP00000011447	ENSOARP00000021568	Protein kinase domain-containing protein.	Synaptonemal complex protein 1.	0.404
CDK2	TERF2	ENSOARP00000011447	ENSOARP00000003807	Protein kinase domain-containing protein.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.449
CDK2	TOP2A	ENSOARP00000011447	ENSOARP00000015382	Protein kinase domain-containing protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.659
CDK7	CDK2	ENSOARP00000006130	ENSOARP00000011447	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.981
CDK7	PCNA	ENSOARP00000006130	ENSOARP00000018385	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.402
CDK7	RAD51	ENSOARP00000006130	ENSOARP00000021748	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.400
CDK7	TAF10	ENSOARP00000006130	ENSOARP00000018441	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	TATA-box binding protein associated factor 10.	0.751
CDK7	TAF3	ENSOARP00000006130	ENSOARP00000014943	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	TATA-box binding protein associated factor 3.	0.764
CDK7	TAF4	ENSOARP00000006130	ENSOARP00000015964	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	TATA-box binding protein associated factor 4.	0.793
CDK7	TBPL1	ENSOARP00000006130	ENSOARP00000015709	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	TATA-box binding protein like 1.	0.500
CTCF	STAG3	ENSOARP00000003248	ENSOARP00000018490	CCCTC-binding factor.	Stromal antigen 3.	0.547
CTCF	TAF3	ENSOARP00000003248	ENSOARP00000014943	CCCTC-binding factor.	TATA-box binding protein associated factor 3.	0.413
KDM3A	ANKRD37	ENSOARP00000022208	ENSOARP00000008375	Lysine demethylase 3A.	Ankyrin repeat domain 37.	0.480