23 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STAP1	Signal transducing adaptor family member 1. (293 aa)
	FCGR1A	Uncharacterized protein. (350 aa)
	W5Q8Q5_SHEEP	GUCT domain-containing protein. (116 aa)
	DDX1	DEAD-box helicase 1. (736 aa)
	W5Q0J0_SHEEP	GUCT domain-containing protein. (145 aa)
	DDX58	DExD/H-box helicase 58. (943 aa)
	ARG1	Arginase. (352 aa)
	ITGB2	Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (750 aa)
	F2RL1	F2R like trypsin receptor 1. (368 aa)
	W5PP49_SHEEP	GUCT domain-containing protein. (129 aa)
	ITGAM	VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1149 aa)
	CD177	CD177 molecule. (441 aa)
	SPI1	Spi-1 proto-oncogene. (260 aa)
	W5P5T4_SHEEP	NTR domain-containing protein. (901 aa)
	DDX21	Uncharacterized protein. (783 aa)
	TYROBP	TYRO protein tyrosine kinase binding protein. (109 aa)
	W5P1J7_SHEEP	GUCT domain-containing protein. (124 aa)
	DHX36	DEAH-box helicase 36. (1065 aa)
	W5NXP6_SHEEP	Anaphylatoxin-like domain-containing protein. (122 aa)
	W5NXM1_SHEEP	A2M domain-containing protein. (152 aa)
	W5NRI1_SHEEP	A2M_N_2 domain-containing protein. (680 aa)
	W5NRH2_SHEEP	Anaphylatoxin-like domain-containing protein. (126 aa)
	W5NPK5_SHEEP	A2M_recep domain-containing protein. (653 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARG1	ITGAM	ENSOARP00000014964	ENSOARP00000009667	Arginase.	VWFA domain-containing protein; Belongs to the integrin alpha chain family.	0.694
DDX1	DDX21	ENSOARP00000017583	ENSOARP00000005698	DEAD-box helicase 1.	Uncharacterized protein.	0.811
DDX1	DHX36	ENSOARP00000017583	ENSOARP00000003754	DEAD-box helicase 1.	DEAH-box helicase 36.	0.979
DDX1	W5P1J7_SHEEP	ENSOARP00000017583	ENSOARP00000004296	DEAD-box helicase 1.	GUCT domain-containing protein.	0.563
DDX1	W5PP49_SHEEP	ENSOARP00000017583	ENSOARP00000012225	DEAD-box helicase 1.	GUCT domain-containing protein.	0.563
DDX1	W5Q0J0_SHEEP	ENSOARP00000017583	ENSOARP00000016226	DEAD-box helicase 1.	GUCT domain-containing protein.	0.563
DDX1	W5Q8Q5_SHEEP	ENSOARP00000017583	ENSOARP00000019097	DEAD-box helicase 1.	GUCT domain-containing protein.	0.563
DDX21	DDX1	ENSOARP00000005698	ENSOARP00000017583	Uncharacterized protein.	DEAD-box helicase 1.	0.811
DDX21	DHX36	ENSOARP00000005698	ENSOARP00000003754	Uncharacterized protein.	DEAH-box helicase 36.	0.907
DHX36	DDX1	ENSOARP00000003754	ENSOARP00000017583	DEAH-box helicase 36.	DEAD-box helicase 1.	0.979
DHX36	DDX21	ENSOARP00000003754	ENSOARP00000005698	DEAH-box helicase 36.	Uncharacterized protein.	0.907
DHX36	W5P1J7_SHEEP	ENSOARP00000003754	ENSOARP00000004296	DEAH-box helicase 36.	GUCT domain-containing protein.	0.652
DHX36	W5PP49_SHEEP	ENSOARP00000003754	ENSOARP00000012225	DEAH-box helicase 36.	GUCT domain-containing protein.	0.652
DHX36	W5Q0J0_SHEEP	ENSOARP00000003754	ENSOARP00000016226	DEAH-box helicase 36.	GUCT domain-containing protein.	0.652
DHX36	W5Q8Q5_SHEEP	ENSOARP00000003754	ENSOARP00000019097	DEAH-box helicase 36.	GUCT domain-containing protein.	0.652
ITGAM	ARG1	ENSOARP00000009667	ENSOARP00000014964	VWFA domain-containing protein; Belongs to the integrin alpha chain family.	Arginase.	0.694
ITGAM	ITGB2	ENSOARP00000009667	ENSOARP00000013259	VWFA domain-containing protein; Belongs to the integrin alpha chain family.	Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...]	0.999
ITGAM	TYROBP	ENSOARP00000009667	ENSOARP00000005542	VWFA domain-containing protein; Belongs to the integrin alpha chain family.	TYRO protein tyrosine kinase binding protein.	0.512
ITGAM	W5NRI1_SHEEP	ENSOARP00000009667	ENSOARP00000000771	VWFA domain-containing protein; Belongs to the integrin alpha chain family.	A2M_N_2 domain-containing protein.	0.922
ITGB2	ITGAM	ENSOARP00000013259	ENSOARP00000009667	Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...]	VWFA domain-containing protein; Belongs to the integrin alpha chain family.	0.999