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| | ANGPT1 | Angiopoietin 1. (485 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (755 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (204 aa) |
| | FGFBP3 | Uncharacterized protein. (68 aa) |
| | W5PZL0_SHEEP | Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (613 aa) |
| | ACTA2 | Actin alpha 2, smooth muscle. (377 aa) |
| | W5PZE0_SHEEP | Uncharacterized protein. (85 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (892 aa) |
| | W5PYT1_SHEEP | Uncharacterized protein. (650 aa) |
| | ADRB2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (419 aa) |
| | DDAH1 | Dimethylarginine dimethylaminohydrolase 1. (337 aa) |
| | SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (367 aa) |
| | SERPINF2 | Serpin family F member 2; Belongs to the serpin family. (491 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (215 aa) |
| | ZDHHC21 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa) |
| | RHOA | RHOA. (193 aa) |
| | ADRB1 | Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity). (430 aa) |
| | PRKG1 | Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (471 aa) |
| | W5PVP9_SHEEP | Uncharacterized protein. (109 aa) |
| | SLC1A1 | Amino acid transporter. (524 aa) |
| | SMTNL2 | Smoothelin like 2. (353 aa) |
| | TBXA2R | Thromboxane A2 receptor. (305 aa) |
| | W5NRV5_SHEEP | Uncharacterized protein. (67 aa) |
| | C2CD4B | Uncharacterized protein. (76 aa) |
| | TJP2 | Uncharacterized protein; Belongs to the MAGUK family. (1211 aa) |
| | TRPM4 | Transient receptor potential cation channel subfamily M member 4. (1202 aa) |
| | ENSOARP00000000911 | annotation not available (76 aa) |
| | W5NRX4_SHEEP | Uncharacterized protein. (87 aa) |
| | ADRB3 | Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis. (395 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | AVPR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (331 aa) |
| | EXT2 | Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (737 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (758 aa) |
| | W5NYJ5_SHEEP | Cu2_monoox_C domain-containing protein. (278 aa) |
| | SNTA1 | Syntrophin alpha 1. (598 aa) |
| | CRP | Pentaxin. (224 aa) |
| | DRD5 | Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (471 aa) |
| | ARHGAP42 | Rho GTPase activating protein 42. (872 aa) |
| | SCPEP1 | Carboxypeptidase; Belongs to the peptidase S10 family. (452 aa) |
| | GCLC | Glutamate-cysteine ligase catalytic subunit. (588 aa) |
| | W5P8R1_SHEEP | G_PROTEIN_RECEP_F1_2 domain-containing protein. (358 aa) |
| | PDE2A | Phosphodiesterase. (938 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa) |
| | HTR1A | G_PROTEIN_RECEP_F1_2 domain-containing protein. (422 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (372 aa) |
| | SLIT2 | Slit guidance ligand 2. (1402 aa) |
| | SOD1-2 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (152 aa) |
| | NOS1 | Nitric oxide synthase, brain; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (By similarity); Belongs to the NOS family. (1463 aa) |
| | W5P0G0_SHEEP | Uncharacterized protein. (97 aa) |
| | RAMP2 | Receptor activity modifying protein 2. (177 aa) |
| | AGT | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. (485 aa) |
| | VSTM4 | V-set and transmembrane domain containing 4. (321 aa) |
| | ABCG2 | ABC transporter domain-containing protein. (685 aa) |
| | PTP4A3 | Protein tyrosine phosphatase 4A3. (171 aa) |
| | PLEC-2 | Uncharacterized protein. (73 aa) |
| | DOCK4 | Dedicator of cytokinesis 4; Belongs to the DOCK family. (1973 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (456 aa) |
| | ADRA1D | Adrenoceptor alpha 1D. (564 aa) |
| | FGB | Fibrinogen beta chain. (497 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa) |
| | MYLK3 | Myosin light chain kinase 3. (782 aa) |
| | HTR7 | 5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (450 aa) |
| | PLEC | Plectin. (4278 aa) |
| | W5Q2Y4_SHEEP | Uncharacterized protein. (272 aa) |
| | BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (387 aa) |
| | W5Q4M2_SHEEP | Uncharacterized protein. (193 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (524 aa) |
| | TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (1750 aa) |
| | HRH2 | Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (304 aa) |
| | FGG | Fibrinogen gamma chain. (434 aa) |
| | W5Q5E0_SHEEP | G_PROTEIN_RECEP_F1_2 domain-containing protein. (330 aa) |
| | FGA | Fibrinogen alpha chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it [...] (812 aa) |
| | SCNN1B | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] (632 aa) |
| | PLVAP | Plasmalemma vesicle associated protein. (445 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa) |
| | GCLM | Glutamate-cysteine ligase modifier subunit. (272 aa) |
| | BMP6 | Bone morphogenetic protein 6. (340 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1040 aa) |
| | CHRM3 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa) |
| | P2RX1 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa) |
| | GPER1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (168 aa) |
| | SLC16A2 | Solute carrier family 16 member 2. (399 aa) |
| | NPPA | Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family. (152 aa) |
| | BBS2 | Bardet-Biedl syndrome 2 protein homolog. (721 aa) |
| | HTR1D | G_PROTEIN_RECEP_F1_2 domain-containing protein. (377 aa) |
| | GRIP2 | Glutamate receptor interacting protein 2. (1020 aa) |
| | SLC1A2 | Amino acid transporter. (574 aa) |
| | VAMP2 | V-SNARE coiled-coil homology domain-containing protein. (110 aa) |
| | KLF2 | Uncharacterized protein. (112 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa) |
| | SLC5A6 | Solute carrier family 5 member 6; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (638 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1500 aa) |
| | UCN | Urocortin. (129 aa) |
| | HTR1B | 5-hydroxytryptamine receptor 1B. (389 aa) |
| | CASR | Calcium sensing receptor. (1032 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (514 aa) |
| | EDN2 | Endothelin 2. (180 aa) |
| | SLC2A1 | Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. (492 aa) |
| | KNG1 | Kininogen 1. (619 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (538 aa) |
| | C2CD4D | C2 domain-containing protein. (110 aa) |
| | FERMT2 | Fermitin family member 2. (687 aa) |
| | ACTG2 | Actin gamma 2, smooth muscle. (376 aa) |
| | SLC5A1 | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. (664 aa) |
| | TJP3 | Tight junction protein 3; Belongs to the MAGUK family. (887 aa) |
| | F2RL1 | F2R like trypsin receptor 1. (368 aa) |
| | DRD1 | Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (409 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (585 aa) |
| | COMP | Cartilage oligomeric matrix protein. (739 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1520 aa) |
| | SLC1A3 | Amino acid transporter. (542 aa) |
| | ADRA2A | Adrenoceptor alpha 2A. (391 aa) |
| | SLC27A4 | Solute carrier family 27 member 4. (649 aa) |
| | ADRA1B | Adrenoceptor alpha 1B. (296 aa) |
| | MKKS | McKusick-Kaufman syndrome. (572 aa) |
| | UTS2 | Uncharacterized protein. (112 aa) |
| | SMTNL1 | Calponin-homology (CH) domain-containing protein. (162 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (748 aa) |
| | AGTR2 | Type-2 angiotensin II receptor; Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (By similarity). (362 aa) |
| | W5PJ80_SHEEP | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (263 aa) |
| | ADRA1A | Adrenoceptor alpha 1A. (432 aa) |
| | W5PJ04_SHEEP | Uncharacterized protein. (191 aa) |
| | ABCC1 | ATP binding cassette subfamily C member 1. (1523 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) |
| | KCNMA1 | Potassium calcium-activated channel subfamily M alpha 1. (1073 aa) |
| | FABP5 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (140 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1372 aa) |
| | C2CD4C | C2 calcium dependent domain containing 4C. (290 aa) |
| | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1211 aa) |
| | EDNRA | Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity). (427 aa) |
| | SOD1 | Superoxide dismutase 1. (152 aa) |
