STRINGSTRING
DCTN1 DCTN1 CHMP1A CHMP1A SPAG4 SPAG4 CHMP4C CHMP4C CHMP7 CHMP7 NUP155 NUP155 DMPK DMPK LEMD2 LEMD2 REEP4 REEP4 W5PLV7_SHEEP W5PLV7_SHEEP W5PM25_SHEEP W5PM25_SHEEP SPAST SPAST W5PN51_SHEEP W5PN51_SHEEP UBXN2B UBXN2B SUN2 SUN2 W5QII7_SHEEP W5QII7_SHEEP LOC101107266 LOC101107266 ZMPSTE24 ZMPSTE24 NUP93 NUP93 NSFL1C NSFL1C LMNB1 LMNB1 GPER1 GPER1 TOR1AIP1 TOR1AIP1 UBXN2A UBXN2A PLK1 PLK1 CHMP2B CHMP2B SUN3 SUN3 NEMP2 NEMP2 PAFAH1B1 PAFAH1B1 CTDNEP1 CTDNEP1 CHMP6 CHMP6 TMEM43 TMEM43 BANF1 BANF1 LEMD3 LEMD3 AKAP8L AKAP8L CHMP2A CHMP2A TARDBP TARDBP EMD EMD SUN5 SUN5 LMNA LMNA SUN1 SUN1 TMEM170A TMEM170A NEMP1 NEMP1 TOR1A TOR1A TOR1B TOR1B CHMP5 CHMP5 ANKLE2 ANKLE2 LMNB2 LMNB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DCTN1CAP-Gly domain-containing protein. (1297 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
SPAG4Sperm associated antigen 4. (440 aa)
CHMP4CCharged multivesicular body protein 4C. (236 aa)
CHMP7Charged multivesicular body protein 7. (452 aa)
NUP155Nucleoporin 155. (1394 aa)
DMPKDM1 protein kinase. (513 aa)
LEMD2LEM domain containing 2. (301 aa)
REEP4Receptor expression-enhancing protein. (261 aa)
W5PLV7_SHEEPUncharacterized protein. (335 aa)
W5PM25_SHEEPUncharacterized protein. (162 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (624 aa)
W5PN51_SHEEPUncharacterized protein. (219 aa)
UBXN2BUBX domain protein 2B. (309 aa)
SUN2Sad1 and UNC84 domain containing 2. (804 aa)
W5QII7_SHEEPUncharacterized protein. (217 aa)
LOC101107266Uncharacterized protein. (222 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (824 aa)
NSFL1CNSFL1 cofactor. (370 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (168 aa)
TOR1AIP1Torsin 1A interacting protein 1. (579 aa)
UBXN2AUBX domain protein 2A. (258 aa)
PLK1Serine/threonine-protein kinase PLK. (605 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
SUN3Sad1 and UNC84 domain containing 3. (359 aa)
NEMP2Nuclear envelope integral membrane protein 2. (390 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (244 aa)
CHMP6Charged multivesicular body protein 6. (180 aa)
TMEM43Transmembrane protein 43. (400 aa)
BANF1Barrier to autointegration factor 1. (89 aa)
LEMD3LEM domain containing 3. (856 aa)
AKAP8LA-kinase anchoring protein 8 like; Belongs to the AKAP95 family. (711 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
TARDBPUncharacterized protein. (415 aa)
EMDEmerin. (206 aa)
SUN5Sad1 and UNC84 domain containing 5. (380 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (658 aa)
SUN1Sad1 and UNC84 domain containing 1. (814 aa)
TMEM170AUncharacterized protein. (106 aa)
NEMP1Nuclear envelope integral membrane protein 1. (487 aa)
TOR1ATorsin family 1 member A. (362 aa)
TOR1BTorsin family 1 member B. (276 aa)
CHMP5Uncharacterized protein. (221 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (975 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (539 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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