STRINGSTRING
FBXW9 FBXW9 W5PQY7_SHEEP W5PQY7_SHEEP BUB1 BUB1 W5PYF0_SHEEP W5PYF0_SHEEP ESCO2 ESCO2 SGO1 SGO1 SGO2 SGO2 DSCC1 DSCC1 GPN3 GPN3 STAG3 STAG3 HASPIN HASPIN HDAC8 HDAC8 RAD21L1 RAD21L1 REC8 REC8 SMC1B SMC1B NAA50 NAA50 BUB1B BUB1B CDC20 CDC20 HORMAD1 HORMAD1 POGZ POGZ PDS5A PDS5A W5NX36_SHEEP W5NX36_SHEEP MRE11 MRE11 STAG2 STAG2 MCMBP MCMBP GPN2 GPN2 FBXW7 FBXW7 PHB2 PHB2 CHTF8 CHTF8 KIF22 KIF22 HORMAD2 HORMAD2 STAG1 STAG1 RB1 RB1 MAU2 MAU2 ESCO1 ESCO1 SMC1A SMC1A SMC3 SMC3 RAD21 RAD21 NIPBL NIPBL PDS5B PDS5B DDX11 DDX11 RAD51C RAD51C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBXW9F-box and WD repeat domain containing 9. (450 aa)
W5PQY7_SHEEPUncharacterized protein. (393 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1081 aa)
W5PYF0_SHEEPShugoshin_C domain-containing protein. (378 aa)
ESCO2Establishment of sister chromatid cohesion N-acetyltransferase 2. (734 aa)
SGO1Shugoshin_C domain-containing protein. (521 aa)
SGO2Shugoshin 2. (1245 aa)
DSCC1DNA replication and sister chromatid cohesion 1. (324 aa)
GPN3GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (150 aa)
STAG3Stromal antigen 3. (1275 aa)
HASPINHistone H3 associated protein kinase. (721 aa)
HDAC8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (446 aa)
RAD21L1RAD21 cohesin complex component like 1. (554 aa)
REC8REC8 meiotic recombination protein. (592 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
NAA50N(alpha)-acetyltransferase 50, NatE catalytic subunit. (169 aa)
BUB1BUncharacterized protein. (1062 aa)
CDC20Cell division cycle 20. (504 aa)
HORMAD1HORMA domain containing 1. (393 aa)
POGZPogo transposable element derived with ZNF domain. (1413 aa)
PDS5APDS5 cohesin associated factor A. (1337 aa)
W5NX36_SHEEPHELICc2 domain-containing protein. (179 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
STAG2Stromal antigen 2. (1233 aa)
MCMBPMinichromosome maintenance complex binding protein. (645 aa)
GPN2GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (285 aa)
FBXW7F-box and WD repeat domain containing 7. (709 aa)
PHB2Prohibitin. (270 aa)
CHTF8Chromosome transmission fidelity factor 8. (138 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (682 aa)
HORMAD2HORMA domain containing 2. (308 aa)
STAG1Stromal antigen 1. (1258 aa)
RB1RB transcriptional corepressor 1. (939 aa)
MAU2MAU2 sister chromatid cohesion factor. (622 aa)
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (841 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
RAD21RAD21 cohesin complex component. (630 aa)
NIPBLNipped-B protein. (2804 aa)
PDS5BPDS5 cohesin associated factor B. (1449 aa)
DDX11DEAD/H-box helicase 11. (903 aa)
RAD51CRAD51 paralog C. (384 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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