47 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DMC1	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa)
	TEX15	Testis expressed 15, meiosis and synapsis associated. (3179 aa)
	MLH3	MutL homolog 3. (1485 aa)
	MRE11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
	TERB1	Telomere repeat binding bouquet formation protein 1. (732 aa)
	PSMC3IP	PSMC3 interacting protein. (217 aa)
	MND1	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (204 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1268 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (411 aa)
	FANCD2	FA complementation group D2. (1454 aa)
	W5P5E4_SHEEP	DNA_MISMATCH_REPAIR_2 domain-containing protein. (835 aa)
	SUN1	Sad1 and UNC84 domain containing 1. (814 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (404 aa)
	NDC1	NDC1 transmembrane nucleoporin. (676 aa)
	MEI4	Meiotic double-stranded break formation protein 4. (395 aa)
	BAG6	BCL2 associated athanogene 6. (1152 aa)
	W5PBQ6_SHEEP	Uncharacterized protein. (171 aa)
	MEIOC	Meiosis specific with coiled-coil domain. (963 aa)
	SYCE2	Synaptonemal complex central element protein 2. (184 aa)
	MAJIN	Membrane anchored junction protein. (257 aa)
	MAEL	Maelstrom spermatogenic transposon silencer. (437 aa)
	MSH4	MutS homolog 4. (935 aa)
	CCDC155	Coiled-coil domain containing 155. (564 aa)
	SYCE1	Synaptonemal complex central element protein 1. (323 aa)
	UBE2B	Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	CCDC36	Coiled-coil domain containing 36. (599 aa)
	TEX11	Testis expressed 11. (920 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (409 aa)
	BRIP1	BRCA1 interacting protein C-terminal helicase 1. (995 aa)
	C1orf146	Chromosome 1 open reading frame 146. (181 aa)
	TEX12	Testis expressed 12. (123 aa)
	MEIOB	Uncharacterized protein. (202 aa)
	ANKRD31	ANK_REP_REGION domain-containing protein. (1276 aa)
	SPATA22	Spermatogenesis associated 22. (326 aa)
	ZCWPW1	Zinc finger CW-type and PWWP domain containing 1. (646 aa)
	STAG3	Stromal antigen 3. (1275 aa)
	SIRT7	Sirtuin 7. (323 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (395 aa)
	RAD21L1	RAD21 cohesin complex component like 1. (554 aa)
	REC8	REC8 meiotic recombination protein. (592 aa)
	RNF212B	Ring finger protein 212B. (300 aa)
	AGO4	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (871 aa)
	CCNB1IP1	Cyclin B1 interacting protein 1. (277 aa)
	SYCE3	Synaptonemal complex central element protein 3. (87 aa)
	SYCP1	Synaptonemal complex protein 1. (1000 aa)
	HORMAD1	HORMA domain containing 1. (393 aa)
	C14orf39	Chromosome 14 open reading frame 39. (584 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD31	HORMAD1	ENSOARP00000017933	ENSOARP00000022408	ANK_REP_REGION domain-containing protein.	HORMA domain containing 1.	0.515
ANKRD31	MAJIN	ENSOARP00000017933	ENSOARP00000012121	ANK_REP_REGION domain-containing protein.	Membrane anchored junction protein.	0.530
ANKRD31	MEI4	ENSOARP00000017933	ENSOARP00000007256	ANK_REP_REGION domain-containing protein.	Meiotic double-stranded break formation protein 4.	0.536
ANKRD31	MEIOB	ENSOARP00000017933	ENSOARP00000017923	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.430
ANKRD31	MND1	ENSOARP00000017933	ENSOARP00000003191	ANK_REP_REGION domain-containing protein.	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.	0.477
ANKRD31	MSH4	ENSOARP00000017933	ENSOARP00000013633	ANK_REP_REGION domain-containing protein.	MutS homolog 4.	0.483
ANKRD31	REC8	ENSOARP00000017933	ENSOARP00000020623	ANK_REP_REGION domain-containing protein.	REC8 meiotic recombination protein.	0.428
ANKRD31	SPO11	ENSOARP00000017933	ENSOARP00000019324	ANK_REP_REGION domain-containing protein.	SPO11 initiator of meiotic double stranded breaks.	0.527
ANKRD31	STAG3	ENSOARP00000017933	ENSOARP00000018490	ANK_REP_REGION domain-containing protein.	Stromal antigen 3.	0.419
ANKRD31	SYCE1	ENSOARP00000017933	ENSOARP00000014418	ANK_REP_REGION domain-containing protein.	Synaptonemal complex central element protein 1.	0.628
ANKRD31	SYCE2	ENSOARP00000017933	ENSOARP00000010843	ANK_REP_REGION domain-containing protein.	Synaptonemal complex central element protein 2.	0.442
ANKRD31	SYCP1	ENSOARP00000017933	ENSOARP00000021568	ANK_REP_REGION domain-containing protein.	Synaptonemal complex protein 1.	0.664
ANKRD31	W5P5E4_SHEEP	ENSOARP00000017933	ENSOARP00000005647	ANK_REP_REGION domain-containing protein.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.416
BRIP1	DMC1	ENSOARP00000017303	ENSOARP00000016725	BRCA1 interacting protein C-terminal helicase 1.	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.472
BRIP1	FANCD2	ENSOARP00000017303	ENSOARP00000005599	BRCA1 interacting protein C-terminal helicase 1.	FA complementation group D2.	0.586
BRIP1	MEIOB	ENSOARP00000017303	ENSOARP00000017923	BRCA1 interacting protein C-terminal helicase 1.	Uncharacterized protein.	0.492
BRIP1	MRE11	ENSOARP00000017303	ENSOARP00000002235	BRCA1 interacting protein C-terminal helicase 1.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.849
C14orf39	SYCE1	ENSOARP00000022707	ENSOARP00000014418	Chromosome 14 open reading frame 39.	Synaptonemal complex central element protein 1.	0.418
C14orf39	SYCE2	ENSOARP00000022707	ENSOARP00000010843	Chromosome 14 open reading frame 39.	Synaptonemal complex central element protein 2.	0.407
CCDC155	DMC1	ENSOARP00000013861	ENSOARP00000016725	Coiled-coil domain containing 155.	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.703