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| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (382 aa) |
| | RAB33A | RAB33A, member RAS oncogene family. (237 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1733 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | GNA13 | G protein subunit alpha 13. (294 aa) |
| | RAP2B | RAP2B, member of RAS oncogene family. (183 aa) |
| | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1183 aa) |
| | W5Q034_SHEEP | N-terminal Ras-GEF domain-containing protein. (127 aa) |
| | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1. (1256 aa) |
| | NF1 | Neurofibromin 1. (2824 aa) |
| | W5PZ15_SHEEP | Uncharacterized protein. (180 aa) |
| | TMEM19 | Transmembrane protein 19. (335 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (395 aa) |
| | LOC101104530 | Uncharacterized protein. (200 aa) |
| | RHOA | RHOA. (193 aa) |
| | CDC42EP1 | CDC42 effector protein 1. (312 aa) |
| | CDKN1A | Uncharacterized protein. (163 aa) |
| | DBNL | Drebrin like. (440 aa) |
| | CDC42EP4 | CDC42 effector protein 4. (327 aa) |
| | RAB33B | RAB33B, member RAS oncogene family. (202 aa) |
| | RAPGEFL1 | Rap guanine nucleotide exchange factor like 1. (576 aa) |
| | RRAS | RAS related. (214 aa) |
| | RALB | RAS like proto-oncogene B. (228 aa) |
| | DOK1 | Docking protein 1. (475 aa) |
| | RAP2C | RAP2C, member of RAS oncogene family. (183 aa) |
| | RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1. (585 aa) |
| | WAS | WASP actin nucleation promoting factor. (464 aa) |
| | PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5. (1040 aa) |
| | RAPGEF5 | Rap guanine nucleotide exchange factor 5. (808 aa) |
| | PDIA2 | Protein disulfide isomerase family A member 2. (540 aa) |
| | ARHGDIG | Rho GDP dissociation inhibitor gamma. (218 aa) |
| | RAB35 | RAB35, member RAS oncogene family. (202 aa) |
| | PDPN | Uncharacterized protein. (168 aa) |
| | RAB39A | RAB39A, member RAS oncogene family. (217 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1520 aa) |
| | CDK2 | Protein kinase domain-containing protein. (298 aa) |
| | DOK2 | Docking protein 2. (262 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (474 aa) |
| | RABGEF1 | Uncharacterized protein. (503 aa) |
| | RASGRP3 | RAS guanyl releasing protein 3. (694 aa) |
| | WASF1 | WASP family member 1. (559 aa) |
| | RAB9B | RAB9B, member RAS oncogene family. (201 aa) |
| | SYNGAP1 | Synaptic Ras GTPase activating protein 1. (1326 aa) |
| | DGKI | Diacylglycerol kinase. (924 aa) |
| | CDH13 | Cadherin 13. (608 aa) |
| | RGL2 | Ral guanine nucleotide dissociation stimulator like 2. (719 aa) |
| | RFXANK | Regulatory factor X associated ankyrin containing protein. (297 aa) |
| | W5PHF9_SHEEP | DEP domain-containing protein. (113 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1372 aa) |
| | RASGRP2 | RAS guanyl releasing protein 2. (667 aa) |
| | KPNB1 | Karyopherin subunit beta 1. (866 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1364 aa) |
| | RB1 | RB transcriptional corepressor 1. (939 aa) |
| | CDC42 | Cell division cycle 42. (237 aa) |
| | AIF1 | Allograft inflammatory factor 1. (147 aa) |
| | MRAS | Muscle RAS oncogene homolog. (209 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (151 aa) |
| | RRAS2 | RAS related 2. (187 aa) |
| | CTNNAL1 | Catenin alpha like 1. (684 aa) |
| | RAB4B | Uncharacterized protein. (215 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1535 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1262 aa) |
| | ARHGAP5 | Rho GTPase activating protein 5. (1503 aa) |
| | W5P836_SHEEP | WH2 domain-containing protein. (638 aa) |
| | EPS8L2 | PID domain-containing protein. (166 aa) |
| | IQGAP3 | IQ motif containing GTPase activating protein 3. (1633 aa) |
| | NGFR | Nerve growth factor receptor. (436 aa) |
| | W5P784_SHEEP | Uncharacterized protein. (191 aa) |
| | ERAS | ES cell expressed Ras. (234 aa) |
| | RAB30 | RAB30, member RAS oncogene family. (203 aa) |
| | RASGRP4 | RAS guanyl releasing protein 4. (673 aa) |
| | LOC101114909 | Death domain-containing protein. (250 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1039 aa) |
| | W5P5M6_SHEEP | Uncharacterized protein. (797 aa) |
| | CNKSR1 | Connector enhancer of kinase suppressor of Ras 1. (710 aa) |
| | BRK1 | Uncharacterized protein. (105 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (833 aa) |
| | RIT1 | Uncharacterized protein. (234 aa) |
| | RAB21 | Uncharacterized protein. (221 aa) |
| | PPP1R21 | Protein phosphatase 1 regulatory subunit 21. (780 aa) |
| | GDI1 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (432 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) |
| | KIAA0355 | KIAA0355. (1024 aa) |
| | GNA12 | G protein subunit alpha 12. (383 aa) |
| | W5P2F2_SHEEP | IRS-type PTB domain-containing protein. (270 aa) |
| | SYNJ2BP | PDZ domain-containing protein. (145 aa) |
| | NISCH | Nischarin. (1494 aa) |
| | RASGEF1A | RasGEF domain family member 1A. (495 aa) |
| | TRIM28 | Tripartite motif containing 28. (835 aa) |
| | W5P130_SHEEP | N-terminal Ras-GEF domain-containing protein. (228 aa) |
| | W5P126_SHEEP | Uncharacterized protein. (228 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2298 aa) |
| | RAB39B | RAB39B, member RAS oncogene family. (258 aa) |
| | ZNF304 | Zinc finger protein 304. (690 aa) |
| | ELMO1 | Engulfment and cell motility 1. (727 aa) |
| | KSR2 | Kinase suppressor of ras 2. (950 aa) |
| | WASF2 | WASP family member 2. (504 aa) |
| | RIPOR1 | RHO family interacting cell polarization regulator 1. (1225 aa) |
| | RAB4A | Uncharacterized protein. (233 aa) |
| | RHOU | Ras homolog family member U. (171 aa) |
| | PHACTR4 | Phosphatase and actin regulator. (716 aa) |
| | RAP2A | RAP2A, member of RAS oncogene family. (183 aa) |
| | CDC42EP5 | CRIB domain-containing protein. (79 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1620 aa) |
| | W5NVW5_SHEEP | Uncharacterized protein. (75 aa) |
| | RGL1 | Ral guanine nucleotide dissociation stimulator like 1. (803 aa) |
| | RAC1 | Uncharacterized protein. (180 aa) |
| | EPS8L1 | EPS8 like 1. (727 aa) |
| | RASGEF1C | RasGEF domain family member 1C. (381 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1364 aa) |
| | LAT | Linker for activation of T cells. (258 aa) |
| | RAP1B | RAP1B, member of RAS oncogene family. (184 aa) |
| | RAPGEF4 | Rap guanine nucleotide exchange factor 4. (1035 aa) |
| | RAB12 | RAB12, member RAS oncogene family. (243 aa) |
| | RHOH | RhoH. (191 aa) |
| | RANGRF | RAN guanine nucleotide release factor. (186 aa) |
| | ADGRG1 | Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (690 aa) |
| | W5NQH3_SHEEP | Protein kinase domain-containing protein. (188 aa) |
| | RASGEF1B | RasGEF domain family member 1B. (552 aa) |
| | RACGAP1 | Rac GTPase activating protein 1. (632 aa) |
| | RAB9A | RAB9A. (203 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (191 aa) |
| | BRAP | BRCA1 associated protein. (699 aa) |
| | GPSM2 | G protein signaling modulator 2. (681 aa) |
| | EPS8L3 | EPS8 like 3. (594 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (925 aa) |
| | CELSR1 | Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2704 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (797 aa) |
| | C15orf62 | Chromosome 15 open reading frame 62. (178 aa) |
| | RHOV | Uncharacterized protein. (168 aa) |
| | BCL6 | BCL6 transcription repressor. (702 aa) |
| | EPS8 | Epidermal growth factor receptor pathway substrate 8. (845 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1311 aa) |
| | RERG | RAS like estrogen regulated growth inhibitor. (199 aa) |
| | ARHGDIB | Rho GDP dissociation inhibitor beta. (200 aa) |
| | USP50 | Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (378 aa) |
| | USP8 | Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1089 aa) |
| | RHOJ | Ras homolog family member J. (236 aa) |
| | RAB15 | RAB15, member RAS oncogene family. (212 aa) |
| | W5QJ76_SHEEP | PDZ domain-containing protein. (124 aa) |
| | ARHGDIA | Rho GDP dissociation inhibitor alpha. (206 aa) |
| | MYO9B | Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2121 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (463 aa) |
| | SHTN1 | Shootin 1. (621 aa) |
| | FARP2 | FERM, ARH/RhoGEF and pleckstrin domain protein 2. (979 aa) |
| | RALA | RAS like proto-oncogene A. (206 aa) |
| | SGSM3 | Small G protein signaling modulator 3. (744 aa) |
| | TAX1BP3 | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1546 aa) |
| | NCKAP1 | NCK associated protein 1. (1126 aa) |
| | W5Q4M2_SHEEP | Uncharacterized protein. (193 aa) |
| | CDC42EP3 | CDC42 effector protein 3. (254 aa) |
| | RASSF1 | Uncharacterized protein. (268 aa) |
| | RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2. (557 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa) |
| | W5Q2U3_SHEEP | Phorbol-ester/DAG-type domain-containing protein. (926 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1254 aa) |
| | PLEKHG7 | Chromosome 12 open reading frame 74. (414 aa) |
| | W5Q2I6_SHEEP | Uncharacterized protein. (194 aa) |
