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| | TNNI1 | Troponin I1, slow skeletal type. (189 aa) |
| | AGTRAP | Angiotensin II receptor associated protein. (159 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (456 aa) |
| | ADRA1D | Adrenoceptor alpha 1D. (564 aa) |
| | FGB | Fibrinogen beta chain. (497 aa) |
| | RANGRF | RAN guanine nucleotide release factor. (186 aa) |
| | GPR37L1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (206 aa) |
| | SMTNL2 | Smoothelin like 2. (353 aa) |
| | SCN3B | Sodium voltage-gated channel beta subunit 3. (215 aa) |
| | W5NRV5_SHEEP | Uncharacterized protein. (67 aa) |
| | C2CD4B | Uncharacterized protein. (76 aa) |
| | NPR1 | Guanylate cyclase. (1064 aa) |
| | ENSOARP00000000911 | annotation not available (76 aa) |
| | W5NRX4_SHEEP | Uncharacterized protein. (87 aa) |
| | W5NS14_SHEEP | BHLH domain-containing protein. (132 aa) |
| | W5NSG0_SHEEP | Uncharacterized protein. (41 aa) |
| | NOX1 | NADPH oxidase 1. (593 aa) |
| | ADRB3 | Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis. (395 aa) |
| | W5NT88_SHEEP | Uncharacterized protein; Belongs to the actin family. (339 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | KCNH2 | Potassium voltage-gated channel subfamily H member 2. (739 aa) |
| | AVPR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (331 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1932 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1364 aa) |
| | EXT2 | Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (737 aa) |
| | W5NUQ0_SHEEP | Uncharacterized protein. (234 aa) |
| | TNNI3 | Troponin I3, cardiac type. (212 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (758 aa) |
| | VSTM4 | V-set and transmembrane domain containing 4. (321 aa) |
| | NOS3 | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity). (1205 aa) |
| | W5NVG7_SHEEP | Myosin_tail_1 domain-containing protein. (128 aa) |
| | REN | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. (406 aa) |
| | GAA | Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (930 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | PTP4A3 | Protein tyrosine phosphatase 4A3. (171 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa) |
| | PLEC-2 | Uncharacterized protein. (73 aa) |
| | KCNQ1 | Ion_trans domain-containing protein; Belongs to the potassium channel family. (383 aa) |
| | E2F4 | E2F transcription factor 4. (469 aa) |
| | DOCK4 | Dedicator of cytokinesis 4; Belongs to the DOCK family. (1973 aa) |
| | W5NYJ5_SHEEP | Cu2_monoox_C domain-containing protein. (278 aa) |
| | AGT | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. (485 aa) |
| | IMMP2L | Uncharacterized protein. (80 aa) |
| | RAMP2 | Receptor activity modifying protein 2. (177 aa) |
| | W5P0G0_SHEEP | Uncharacterized protein. (97 aa) |
| | ENPEP | Aminopeptidase. (953 aa) |
| | SUCNR1 | Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (329 aa) |
| | RYR2 | Ryanodine receptor 2. (4788 aa) |
| | TNNI2 | Troponin I2, fast skeletal type. (203 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa) |
| | W5P203_SHEEP | Uncharacterized protein. (66 aa) |
| | NOS1 | Nitric oxide synthase, brain; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (By similarity); Belongs to the NOS family. (1463 aa) |
| | STK39 | Serine/threonine kinase 39. (390 aa) |
| | SOD1-2 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (152 aa) |
| | TNNC1 | Troponin C1, slow skeletal and cardiac type. (161 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. The activity of isoform FSH-R1 is mediated by G proteins which activate adenylate cyclase. Isoform FSH-R2 and isoform FSH-R3 also bind FSH, but this does not result in activation of adenylate cyclase. Isoform FSH-R3 may be involved in calcium signaling. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (By similarity). (656 aa) |
| | GNA12 | G protein subunit alpha 12. (383 aa) |
| | SCN1B | Sodium voltage-gated channel beta subunit 1. (237 aa) |
| | SLIT2 | Slit guidance ligand 2. (1402 aa) |
| | SCN1A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2001 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (372 aa) |
| | W5P4X8_SHEEP | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (615 aa) |
| | TBX20 | T-box transcription factor 20. (399 aa) |
| | CARTPT | CART prepropeptide. (90 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (182 aa) |
| | CPA3 | Carboxypeptidase A3. (418 aa) |
| | HTR1A | G_PROTEIN_RECEP_F1_2 domain-containing protein. (422 aa) |
| | GSN | Uncharacterized protein. (782 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa) |
| | KCNK6 | Potassium channel subfamily K member. (312 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1213 aa) |
| | PDE2A | Phosphodiesterase. (938 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (482 aa) |
| | PRCP | Prolylcarboxypeptidase. (497 aa) |
| | RASL10B | RAS like family 10 member B. (237 aa) |
| | W5P8R1_SHEEP | G_PROTEIN_RECEP_F1_2 domain-containing protein. (358 aa) |
| | OR51E2 | Olfactory receptor. (320 aa) |
| | KCNE3 | Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa) |
| | MYL3 | Myosin light chain 3. (199 aa) |
| | GCLC | Glutamate-cysteine ligase catalytic subunit. (588 aa) |
| | SCPEP1 | Carboxypeptidase; Belongs to the peptidase S10 family. (452 aa) |
| | OXTR | Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (368 aa) |
| | ARHGAP42 | Rho GTPase activating protein 42. (872 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (607 aa) |
| | KCNE1 | Uncharacterized protein. (129 aa) |
| | KCNE2 | Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa) |
| | DRD5 | Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (471 aa) |
| | CRP | Pentaxin. (224 aa) |
| | SNTA1 | Syntrophin alpha 1. (598 aa) |
| | SOD1 | Superoxide dismutase 1. (152 aa) |
| | TAC3 | Uncharacterized protein. (126 aa) |
| | GSK3A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (451 aa) |
| | TRDN | Uncharacterized protein. (281 aa) |
| | CDC42 | Cell division cycle 42. (237 aa) |
| | SCN4B | Sodium voltage-gated channel beta subunit 4. (232 aa) |
| | EDNRA | Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity). (427 aa) |
| | NDST2 | Uncharacterized protein. (879 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1211 aa) |
| | SCN2B | Sodium voltage-gated channel beta subunit 2. (258 aa) |
| | GATA6 | GATA binding protein 6. (613 aa) |
| | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) |
| | C2CD4C | C2 calcium dependent domain containing 4C. (290 aa) |
| | NAV2 | Neuron navigator 2. (2319 aa) |
| | GAS6 | Growth arrest specific 6. (594 aa) |
| | ECE1 | Endothelin converting enzyme 1. (752 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1372 aa) |
| | CSRP3 | Cysteine and glycine-rich protein 3. (194 aa) |
| | KCNMA1 | Potassium calcium-activated channel subfamily M alpha 1. (1073 aa) |
| | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. (303 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) |
| | SGCZ | Uncharacterized protein. (181 aa) |
| | GRK2 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (606 aa) |
| | W5PJ04_SHEEP | Uncharacterized protein. (191 aa) |
| | ADRA1A | Adrenoceptor alpha 1A. (432 aa) |
| | W5PJ80_SHEEP | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (263 aa) |
| | AGTR2 | Type-2 angiotensin II receptor; Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (By similarity). (362 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (748 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (832 aa) |
| | SMTNL1 | Calponin-homology (CH) domain-containing protein. (162 aa) |
| | F5 | Coagulation factor V; Belongs to the multicopper oxidase family. (2066 aa) |
| | NUP155 | Nucleoporin 155. (1394 aa) |
| | UTS2 | Uncharacterized protein. (112 aa) |
| | MKKS | McKusick-Kaufman syndrome. (572 aa) |
| | ADRA1B | Adrenoceptor alpha 1B. (296 aa) |
| | ENSOARP00000011199 | annotation not available (80 aa) |
| | SGCD | Sarcoglycan delta. (289 aa) |
| | ADRA2A | Adrenoceptor alpha 2A. (391 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1520 aa) |
| | NPY | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (84 aa) |
| | COMP | Cartilage oligomeric matrix protein. (739 aa) |
| | P2RX2 | Purinergic receptor P2X 2. (312 aa) |
| | CORO2A | Coronin; Belongs to the WD repeat coronin family. (525 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (585 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | FFAR3 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (326 aa) |
| | ADM | Adrenomedullin. (189 aa) |
| | DRD1 | Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa) |
| | TCAP | Titin-cap. (167 aa) |
| | F2RL1 | F2R like trypsin receptor 1. (368 aa) |
| | W5PQ13_SHEEP | Uncharacterized protein. (433 aa) |
| | MYL4 | Myosin light chain 4. (193 aa) |
| | ANPEP | Aminopeptidase. (968 aa) |
| | TJP3 | Tight junction protein 3; Belongs to the MAGUK family. (887 aa) |
| | W5PR25_SHEEP | Coronin; Belongs to the WD repeat coronin family. (376 aa) |
| | ACTG2 | Actin gamma 2, smooth muscle. (376 aa) |
| | NPR3 | Natriuretic peptide receptor 3. (517 aa) |
| | TBXA2R | Thromboxane A2 receptor. (305 aa) |
| | WNK1 | WNK lysine deficient protein kinase 1. (2337 aa) |
| | SLC4A5 | Anion exchange protein. (1142 aa) |
| | ACE2 | Angiotensin-converting enzyme. (805 aa) |
| | UMOD | Uromodulin. (643 aa) |
| | TRPM4 | Transient receptor potential cation channel subfamily M member 4. (1202 aa) |
| | CACNB2 | Calcium voltage-gated channel auxiliary subunit beta 2. (613 aa) |
| | ACE | Angiotensin-converting enzyme. (1206 aa) |
| | TJP2 | Uncharacterized protein; Belongs to the MAGUK family. (1211 aa) |
| | GNA11 | G protein subunit alpha 11. (314 aa) |
| | W5PU85_SHEEP | Angiotensin-converting enzyme. (624 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2147 aa) |
| | FLI1 | Fli-1 proto-oncogene, ETS transcription factor. (407 aa) |
| | KCNJ5 | Potassium voltage-gated channel subfamily J member 5. (429 aa) |
| | ADM5 | Uncharacterized protein. (107 aa) |
| | SGCG | Sarcoglycan gamma. (291 aa) |
| | PRKG1 | Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (471 aa) |
| | NPY1R | Neuropeptide Y receptor type 1; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family. (383 aa) |
| | ADRB1 | Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity). (430 aa) |
| | KCNJ2 | Potassium voltage-gated channel subfamily J member 2. (427 aa) |
| | RHOA | RHOA. (193 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | ZDHHC21 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (215 aa) |
| | SERPINF2 | Serpin family F member 2; Belongs to the serpin family. (491 aa) |
| | SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (367 aa) |
| | PTGS1 | Prostaglandin G/H synthase 1; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells. (593 aa) |
| | KLK1 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (266 aa) |
| | W5PXT2_SHEEP | Uncharacterized protein. (145 aa) |
| | W5PXT5_SHEEP | Amino_oxidase domain-containing protein. (152 aa) |
| | HRH3 | Histamine receptor H3. (409 aa) |
| | DDAH1 | Dimethylarginine dimethylaminohydrolase 1. (337 aa) |
| | ADRB2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (419 aa) |
| | AR | Androgen receptor. (881 aa) |
| | W5PYT1_SHEEP | Uncharacterized protein. (650 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (892 aa) |
| | ID2 | BHLH domain-containing protein. (149 aa) |
| | MYL10 | Myosin light chain 10. (176 aa) |
| | TRHDE | Aminopeptidase. (871 aa) |
| | W5PZE0_SHEEP | Uncharacterized protein. (85 aa) |
| | ACTA2 | Actin alpha 2, smooth muscle. (377 aa) |
| | FGFBP3 | Uncharacterized protein. (68 aa) |
| | APLN | Apelin. (82 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (204 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (755 aa) |
| | ANGPT1 | Angiopoietin 1. (485 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (385 aa) |
| | GNA13 | G protein subunit alpha 13. (294 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1585 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa) |
| | MYLK3 | Myosin light chain kinase 3. (782 aa) |
| | ADH5 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa) |
| | HTR7 | 5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (450 aa) |
| | PLEC | Plectin. (4278 aa) |
| | W5Q2Y4_SHEEP | Uncharacterized protein. (272 aa) |
| | BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (387 aa) |
| | MYL7 | EF-hand domain-containing protein. (201 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2893 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2148 aa) |
| | CORIN | Corin, serine peptidase. (1067 aa) |
| | KCNN2 | Potassium calcium-activated channel subfamily N member 2. (724 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1071 aa) |
| | GLP1R | Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (252 aa) |
| | W5Q4M2_SHEEP | Uncharacterized protein. (193 aa) |
| | LVRN | Aminopeptidase. (985 aa) |
| | TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (1750 aa) |
| | HRH2 | Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (304 aa) |
| | FGG | Fibrinogen gamma chain. (434 aa) |
| | W5Q5E0_SHEEP | G_PROTEIN_RECEP_F1_2 domain-containing protein. (330 aa) |
| | FGA | Fibrinogen alpha chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it [...] (812 aa) |
| | SCNN1B | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] (632 aa) |
| | PLVAP | Plasmalemma vesicle associated protein. (445 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa) |
| | GCLM | Glutamate-cysteine ligase modifier subunit. (272 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (386 aa) |
| | BMP6 | Bone morphogenetic protein 6. (340 aa) |
| | W5Q741_SHEEP | Uncharacterized protein. (70 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1040 aa) |
| | MYL2 | Myosin light chain 2. (166 aa) |
| | CHRM3 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa) |
| | ERAP1 | Aminopeptidase. (942 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (454 aa) |
| | P2RX1 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa) |
| | ERAP2 | Aminopeptidase. (968 aa) |
| | KCNE5 | Potassium voltage-gated channel subfamily E regulatory subunit 5. (138 aa) |
| | LNPEP | Leucyl and cystinyl aminopeptidase. (1026 aa) |
| | GPER1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (168 aa) |
| | NPPA | Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family. (152 aa) |
| | POMC | Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate. (254 aa) |
| | BBS2 | Bardet-Biedl syndrome 2 protein homolog. (721 aa) |
| | HTR1D | G_PROTEIN_RECEP_F1_2 domain-containing protein. (377 aa) |
| | CORO2B | Coronin; Belongs to the WD repeat coronin family. (480 aa) |
| | GRIP2 | Glutamate receptor interacting protein 2. (1020 aa) |
| | ADM2 | Uncharacterized protein. (38 aa) |
| | W5QBX2_SHEEP | Uncharacterized protein. (238 aa) |
| | BBS4 | Bardet-Biedl syndrome 4. (507 aa) |
| | VAMP2 | V-SNARE coiled-coil homology domain-containing protein. (110 aa) |
| | QRFP | Uncharacterized protein. (131 aa) |
| | EMILIN1 | Elastin microfibril interfacer 1. (990 aa) |
| | KLF2 | Uncharacterized protein. (112 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1500 aa) |
| | PKP2 | Plakophilin 2. (829 aa) |
| | MYH7 | Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (716 aa) |
| | UCN | Urocortin. (129 aa) |
| | KCND3 | Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa) |
| | HTR1B | 5-hydroxytryptamine receptor 1B. (389 aa) |
| | ACTC1 | Actin alpha cardiac muscle 1. (378 aa) |
| | CASR | Calcium sensing receptor. (1032 aa) |
| | CASQ2 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (431 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. (1021 aa) |
| | ABCC9 | ATP binding cassette subfamily C member 9. (1551 aa) |
| | KCNJ8 | Potassium voltage-gated channel subfamily J member 8. (424 aa) |
| | SPX | Spexin hormone. (116 aa) |
| | EDN2 | Endothelin 2. (180 aa) |
| | UTS2B | Urotensin 2B. (119 aa) |
| | ADIPOQ | C1q domain-containing protein. (283 aa) |
| | KNG1 | Kininogen 1. (619 aa) |
| | PTPRO | Protein tyrosine phosphatase receptor type O. (1221 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (538 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa) |
| | C2CD4D | C2 domain-containing protein. (110 aa) |
| | FERMT2 | Fermitin family member 2. (687 aa) |
| | GCH1 | GTP cyclohydrolase 1. (254 aa) |
