STRINGSTRING
TGOLN2 TGOLN2 W5Q0H1_SHEEP W5Q0H1_SHEEP MYO1D MYO1D ARFRP1 ARFRP1 W5PLN5_SHEEP W5PLN5_SHEEP VPS52 VPS52 W5PGH7_SHEEP W5PGH7_SHEEP HOOK1 HOOK1 WDR91 WDR91 LAMP1 LAMP1 RAB6A RAB6A DOP1A DOP1A UBE2O UBE2O SNX6 SNX6 SNF8 SNF8 TBC1D10A TBC1D10A HEATR5A HEATR5A PREPL PREPL TBC1D10B TBC1D10B EMP2 EMP2 RAB14 RAB14 W5PM71_SHEEP W5PM71_SHEEP SNX3 SNX3 HOOK2 HOOK2 TBC1D14 TBC1D14 TBC1D10C TBC1D10C WASHC1 WASHC1 TRAPPC10 TRAPPC10 VPS53 VPS53 RGP1 RGP1 KIF16B KIF16B VTI1A VTI1A VPS51 VPS51 KLHL20 KLHL20 DCTN1 DCTN1 DENND5A DENND5A RILP RILP DENND2A DENND2A CLTC CLTC VPS26B VPS26B RIC1 RIC1 TBC1D17 TBC1D17 GGA1 GGA1 DOP1B DOP1B WDR81 WDR81 W5PY13_SHEEP W5PY13_SHEEP TMEM87B TMEM87B W5PYU2_SHEEP W5PYU2_SHEEP W5PYX8_SHEEP W5PYX8_SHEEP SNX16 SNX16 W5PZ14_SHEEP W5PZ14_SHEEP ARL1 ARL1 GOLT1B GOLT1B W5Q4F6_SHEEP W5Q4F6_SHEEP VPS54 VPS54 CLN5 CLN5 YKT6 YKT6 RAB5A RAB5A SGSM2 SGSM2 EHD3 EHD3 CCDC91 CCDC91 VPS26A VPS26A W5P5F9_SHEEP W5P5F9_SHEEP SNX8 SNX8 FLNA FLNA PIK3C3 PIK3C3 RAB7B RAB7B EPS15 EPS15 RAB29 RAB29 VPS50 VPS50 ANKRD27 ANKRD27 SLC66A2 SLC66A2 RAB7A RAB7A AP1G1 AP1G1 BECN1 BECN1 CORO1A CORO1A SNX2 SNX2 W5QC68_SHEEP W5QC68_SHEEP HOOK3 HOOK3 ANKFY1 ANKFY1 FAM160A2 FAM160A2 W5QB18_SHEEP W5QB18_SHEEP STX6 STX6 RAB9A RAB9A SNX5 SNX5 TBC1D23 TBC1D23 SNX32 SNX32 AKTIP AKTIP AP4M1 AP4M1 STX5 STX5 TRIM27 TRIM27 MAGEL2 MAGEL2 TPCN2 TPCN2 STX16-NPEPL1 STX16-NPEPL1 RBSN RBSN VPS29 VPS29 W5Q3D2_SHEEP W5Q3D2_SHEEP GAK GAK W5NZ01_SHEEP W5NZ01_SHEEP SPAG9 SPAG9 AP1AR AP1AR CLN3 CLN3 WIPI1 WIPI1 STX8 STX8 WASHC2C WASHC2C GOLT1A GOLT1A PIP4K2A PIP4K2A LMTK2 LMTK2 GCC2 GCC2 BET1L BET1L RNF126 RNF126 STX10 STX10 HEATR5B HEATR5B RAB9B RAB9B PPFIA2 PPFIA2 BAIAP3 BAIAP3 VPS35 VPS35 SORT1 SORT1 VTI1B VTI1B ATG14 ATG14 SNX1 SNX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGOLN2Uncharacterized protein. (341 aa)
W5Q0H1_SHEEPUncharacterized protein. (431 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (930 aa)
ARFRP1ADP-ribosylation factor related protein 1. (201 aa)
W5PLN5_SHEEPV-SNARE coiled-coil homology domain-containing protein. (150 aa)
VPS52VPS52 subunit of GARP complex. (724 aa)
W5PGH7_SHEEPV-SNARE coiled-coil homology domain-containing protein. (109 aa)
HOOK1Hook microtubule tethering protein 1. (733 aa)
WDR91WD repeat domain 91. (681 aa)
LAMP1Lysosomal associated membrane protein 1. (392 aa)
RAB6ARAB6A, member RAS oncogene family. (208 aa)
DOP1ADOP1 leucine zipper like protein A. (2467 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1167 aa)
SNX6Sorting nexin 6. (388 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
TBC1D10ATBC1 domain family member 10A. (441 aa)
HEATR5AHEAT repeat containing 5A. (2044 aa)
PREPLProlyl endopeptidase like. (727 aa)
TBC1D10BTBC1 domain family member 10B. (802 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
W5PM71_SHEEPPH domain-containing protein. (183 aa)
SNX3Sorting nexin 3. (162 aa)
HOOK2Hook microtubule tethering protein 2. (719 aa)
TBC1D14TBC1 domain family member 14. (773 aa)
TBC1D10CTBC1 domain family member 10C. (440 aa)
WASHC1WH2 domain-containing protein. (269 aa)
TRAPPC10Foie-gras_1 domain-containing protein. (1265 aa)
VPS53VPS53 subunit of GARP complex. (832 aa)
RGP1RGP1 homolog, RAB6A GEF complex partner 1. (432 aa)
KIF16BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1360 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (224 aa)
VPS51VPS51 subunit of GARP complex. (788 aa)
KLHL20Kelch like family member 20. (622 aa)
DCTN1CAP-Gly domain-containing protein. (1297 aa)
DENND5ADENN domain containing 5A. (1191 aa)
RILPUncharacterized protein. (103 aa)
DENND2ADENN domain containing 2A. (1044 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa)
VPS26BVPS26, retromer complex component B. (213 aa)
RIC1RIC1 homolog, RAB6A GEF complex partner 1. (1422 aa)
TBC1D17TBC1 domain family member 17. (645 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (633 aa)
DOP1BDOP1 leucine zipper like protein B. (2285 aa)
WDR81WD repeat domain 81. (1883 aa)
W5PY13_SHEEPUncharacterized protein. (145 aa)
TMEM87BTransmembrane protein 87B. (492 aa)
W5PYU2_SHEEPProtein kinase domain-containing protein. (697 aa)
W5PYX8_SHEEPUncharacterized protein. (216 aa)
SNX16Sorting nexin 16. (314 aa)
W5PZ14_SHEEPWD_REPEATS_REGION domain-containing protein. (470 aa)
ARL1Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
GOLT1BGolgi transport 1B. (138 aa)
W5Q4F6_SHEEPPX domain-containing protein. (163 aa)
VPS54VPS54 subunit of GARP complex. (979 aa)
CLN5Ceroid-lipofuscinosis neuronal protein 5, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family. (357 aa)
YKT6Uncharacterized protein; Belongs to the synaptobrevin family. (198 aa)
RAB5AUncharacterized protein. (215 aa)
SGSM2Small G protein signaling modulator 2. (1056 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (531 aa)
CCDC91Coiled-coil domain containing 91. (442 aa)
VPS26AVPS26, retromer complex component A. (368 aa)
W5P5F9_SHEEPUncharacterized protein. (136 aa)
SNX8Sorting nexin 8. (419 aa)
FLNAFilamin A. (2633 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (945 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (912 aa)
RAB29RAB29, member RAS oncogene family. (203 aa)
VPS50VPS50 subunit of EARP/GARPII complex. (966 aa)
ANKRD27Ankyrin repeat domain 27. (1048 aa)
SLC66A2Uncharacterized protein. (250 aa)
RAB7ARAS oncogene family-like 7A. (207 aa)
AP1G1AP-1 complex subunit gamma. (842 aa)
BECN1Beclin 1. (448 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
SNX2Sorting nexin 2. (484 aa)
W5QC68_SHEEPUncharacterized protein; Belongs to the synaptobrevin family. (187 aa)
HOOK3Hook microtubule tethering protein 3. (719 aa)
ANKFY1Ankyrin repeat and FYVE domain containing 1. (1174 aa)
FAM160A2Family with sequence similarity 160 member A2. (969 aa)
W5QB18_SHEEPUncharacterized protein. (309 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (257 aa)
RAB9ARAB9A. (203 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
TBC1D23TBC1 domain family member 23. (700 aa)
SNX32Sorting nexin 32. (352 aa)
AKTIPAKT interacting protein. (293 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (455 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (355 aa)
TRIM27Tripartite motif containing 27. (513 aa)
MAGEL2MAGE domain-containing protein. (681 aa)
TPCN2Uncharacterized protein. (721 aa)
STX16-NPEPL1t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (273 aa)
RBSNRabenosyn, RAB effector. (758 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)
W5Q3D2_SHEEPPX domain-containing protein. (168 aa)
GAKCyclin G associated kinase. (1098 aa)
W5NZ01_SHEEPCoronin; Belongs to the WD repeat coronin family. (924 aa)
SPAG9Sperm associated antigen 9. (1325 aa)
AP1ARAdaptor related protein complex 1 associated regulatory protein. (274 aa)
CLN3Battenin. (438 aa)
WIPI1Uncharacterized protein. (68 aa)
STX8Syntaxin 8. (180 aa)
WASHC2CCAP-ZIP_m domain-containing protein. (1332 aa)
GOLT1AGolgi transport 1A. (133 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (404 aa)
LMTK2Lemur tyrosine kinase 2. (1443 aa)
GCC2GRIP and coiled-coil domain containing 2. (1646 aa)
BET1LBet1 golgi vesicular membrane trafficking protein like. (111 aa)
RNF126Ring finger protein 126. (327 aa)
STX10Syntaxin 10. (201 aa)
HEATR5BHEAT repeat containing 5B. (2070 aa)
RAB9BRAB9B, member RAS oncogene family. (201 aa)
PPFIA2PTPRF interacting protein alpha 2. (1223 aa)
BAIAP3BAI1 associated protein 3. (965 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (795 aa)
SORT1Sortilin. (965 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
ATG14Autophagy related 14. (512 aa)
SNX1Sorting nexin 1. (474 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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