36 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRR14L	Proline rich 14 like. (2128 aa)
	PISD	Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (408 aa)
	AMD1	S-adenosylmethionine decarboxylase proenzyme. (338 aa)
	MLYCD	Malonyl-CoA decarboxylase. (353 aa)
	PDXDC1	Pyridoxal dependent decarboxylase domain containing 1. (790 aa)
	ECHDC1	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (307 aa)
	W5PCA2_SHEEP	Uncharacterized protein. (260 aa)
	ME1	Malic enzyme. (545 aa)
	W5P7K2_SHEEP	AIRC domain-containing protein. (438 aa)
	W5P775_SHEEP	Uncharacterized protein. (543 aa)
	W5P484_SHEEP	Uncharacterized protein. (256 aa)
	W5P477_SHEEP	CLLAC domain-containing protein. (152 aa)
	GAD2	Glutamate decarboxylase 2. (578 aa)
	W5P228_SHEEP	AIRC domain-containing protein. (426 aa)
	PPCDC	Phosphopantothenoylcysteine decarboxylase. (220 aa)
	GAD1	Glutamate decarboxylase 1. (599 aa)
	W5NV78_SHEEP	Uncharacterized protein. (125 aa)
	UROD	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (367 aa)
	W5PVY6_SHEEP	Uncharacterized protein. (102 aa)
	DDC	Dopa decarboxylase. (543 aa)
	GADL1	Glutamate decarboxylase like 1. (449 aa)
	ODC1	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
	ACOD1	Aconitate decarboxylase 1. (489 aa)
	CSAD	Uncharacterized protein. (507 aa)
	AZIN1	Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (620 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (724 aa)
	UMPS	Uridine monophosphate synthetase. (484 aa)
	GGCX	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. (758 aa)
	AZIN2	Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (519 aa)
	UXS1	UDP-glucuronate decarboxylase 1. (396 aa)
	HDC	Histidine decarboxylase. (658 aa)
	MVD	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (391 aa)
	W5PS89_SHEEP	OHCU_decarbox domain-containing protein. (173 aa)
	GOT1	Aspartate aminotransferase. (413 aa)
	ACMSD	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACMSD	MLYCD	ENSOARP00000012164	ENSOARP00000010416	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	Malonyl-CoA decarboxylase.	0.836
AMD1	AZIN1	ENSOARP00000010650	ENSOARP00000018246	S-adenosylmethionine decarboxylase proenzyme.	Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.602
AMD1	AZIN2	ENSOARP00000010650	ENSOARP00000022422	S-adenosylmethionine decarboxylase proenzyme.	Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.549
AMD1	ODC1	ENSOARP00000010650	ENSOARP00000016555	S-adenosylmethionine decarboxylase proenzyme.	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.753
AZIN1	AMD1	ENSOARP00000018246	ENSOARP00000010650	Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	S-adenosylmethionine decarboxylase proenzyme.	0.602
AZIN1	GAD2	ENSOARP00000018246	ENSOARP00000005214	Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Glutamate decarboxylase 2.	0.470
AZIN1	GOT1	ENSOARP00000018246	ENSOARP00000013317	Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Aspartate aminotransferase.	0.464
AZIN1	ODC1	ENSOARP00000018246	ENSOARP00000016555	Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.550
AZIN2	AMD1	ENSOARP00000022422	ENSOARP00000010650	Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	S-adenosylmethionine decarboxylase proenzyme.	0.549
AZIN2	GOT1	ENSOARP00000022422	ENSOARP00000013317	Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Aspartate aminotransferase.	0.464
AZIN2	W5NV78_SHEEP	ENSOARP00000022422	ENSOARP00000002074	Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	Uncharacterized protein.	0.458
CSAD	GADL1	ENSOARP00000017905	ENSOARP00000015806	Uncharacterized protein.	Glutamate decarboxylase like 1.	0.901
CSAD	GOT1	ENSOARP00000017905	ENSOARP00000013317	Uncharacterized protein.	Aspartate aminotransferase.	0.848
CSAD	ME1	ENSOARP00000017905	ENSOARP00000008043	Uncharacterized protein.	Malic enzyme.	0.437
DDC	GOT1	ENSOARP00000015447	ENSOARP00000013317	Dopa decarboxylase.	Aspartate aminotransferase.	0.918
GAD1	GAD2	ENSOARP00000002472	ENSOARP00000005214	Glutamate decarboxylase 1.	Glutamate decarboxylase 2.	0.951
GAD1	GOT1	ENSOARP00000002472	ENSOARP00000013317	Glutamate decarboxylase 1.	Aspartate aminotransferase.	0.821
GAD1	W5P775_SHEEP	ENSOARP00000002472	ENSOARP00000006279	Glutamate decarboxylase 1.	Uncharacterized protein.	0.901
GAD2	AZIN1	ENSOARP00000005214	ENSOARP00000018246	Glutamate decarboxylase 2.	Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.470
GAD2	GAD1	ENSOARP00000005214	ENSOARP00000002472	Glutamate decarboxylase 2.	Glutamate decarboxylase 1.	0.951