36 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKAR1A	Uncharacterized protein. (411 aa)
	CNBD2	Cyclic nucleotide binding domain containing 2. (583 aa)
	STING1	Transmembrane protein 173. (378 aa)
	PDE11A	Phosphodiesterase. (914 aa)
	FKBP1B	Peptidylprolyl isomerase. (108 aa)
	PDE6G	Phosphodiesterase 6G. (102 aa)
	CNGA4	Cyclic nucleotide gated channel subunit alpha 4. (570 aa)
	PDE2A	Phosphodiesterase. (938 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (377 aa)
	PDE10A	Phosphodiesterase. (791 aa)
	PDE6C	Phosphodiesterase. (855 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1620 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
	W5NS75_SHEEP	Cyclic nucleotide-binding domain-containing protein. (1315 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (1035 aa)
	PDE4D	Phosphodiesterase. (674 aa)
	PRKG2	cGMP-dependent protein kinase. (762 aa)
	MAP2	Microtubule-associated protein. (1865 aa)
	POPDC2	Popeye domain containing 2. (368 aa)
	PDE6H	Phosphodiesterase 6H. (83 aa)
	HCN1	Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (548 aa)
	CNGA2	Cyclic nucleotide gated channel subunit alpha 2. (663 aa)
	W5PLE2_SHEEP	Uncharacterized protein. (93 aa)
	PDE4B	Phosphodiesterase. (544 aa)
	BVES	Blood vessel epicardial substance. (617 aa)
	CNGB3	Cyclic nucleotide-binding domain-containing protein. (665 aa)
	W5PRK3_SHEEP	Cyclic nucleotide-binding domain-containing protein. (213 aa)
	SLC19A1	Solute carrier family 19 member 1. (508 aa)
	CNGA3	Cyclic nucleotide-binding domain-containing protein. (700 aa)
	PRKG1	Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (471 aa)
	W5PZE0_SHEEP	Uncharacterized protein. (85 aa)
	W5PZF6_SHEEP	PKcGMP_CC domain-containing protein. (82 aa)
	PDE5A	Phosphodiesterase. (865 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (305 aa)
	PDE4A	Phosphodiesterase. (809 aa)
	CNGA1	Cyclic nucleotide gated channel subunit alpha 1. (690 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNGA1	CNGB3	ENSOARP00000017942	ENSOARP00000012474	Cyclic nucleotide gated channel subunit alpha 1.	Cyclic nucleotide-binding domain-containing protein.	0.925
CNGA1	PDE4A	ENSOARP00000017942	ENSOARP00000017441	Cyclic nucleotide gated channel subunit alpha 1.	Phosphodiesterase.	0.510
CNGA1	PDE6C	ENSOARP00000017942	ENSOARP00000003557	Cyclic nucleotide gated channel subunit alpha 1.	Phosphodiesterase.	0.575
CNGA1	PDE6H	ENSOARP00000017942	ENSOARP00000022234	Cyclic nucleotide gated channel subunit alpha 1.	Phosphodiesterase 6H.	0.594
CNGA1	W5NS75_SHEEP	ENSOARP00000017942	ENSOARP00000001015	Cyclic nucleotide gated channel subunit alpha 1.	Cyclic nucleotide-binding domain-containing protein.	0.999
CNGA2	CNGA3	ENSOARP00000009206	ENSOARP00000014559	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide-binding domain-containing protein.	0.547
CNGA2	CNGA4	ENSOARP00000009206	ENSOARP00000020182	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide gated channel subunit alpha 4.	0.994
CNGA2	CNGB3	ENSOARP00000009206	ENSOARP00000012474	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide-binding domain-containing protein.	0.851
CNGA2	PDE2A	ENSOARP00000009206	ENSOARP00000006073	Cyclic nucleotide gated channel subunit alpha 2.	Phosphodiesterase.	0.507
CNGA2	PDE4A	ENSOARP00000009206	ENSOARP00000017441	Cyclic nucleotide gated channel subunit alpha 2.	Phosphodiesterase.	0.513
CNGA2	PDE6C	ENSOARP00000009206	ENSOARP00000003557	Cyclic nucleotide gated channel subunit alpha 2.	Phosphodiesterase.	0.595
CNGA2	PDE6H	ENSOARP00000009206	ENSOARP00000022234	Cyclic nucleotide gated channel subunit alpha 2.	Phosphodiesterase 6H.	0.457
CNGA2	W5NS75_SHEEP	ENSOARP00000009206	ENSOARP00000001015	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide-binding domain-containing protein.	0.977
CNGA3	CNGA2	ENSOARP00000014559	ENSOARP00000009206	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide gated channel subunit alpha 2.	0.547
CNGA3	CNGB3	ENSOARP00000014559	ENSOARP00000012474	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.947
CNGA3	PDE2A	ENSOARP00000014559	ENSOARP00000006073	Cyclic nucleotide-binding domain-containing protein.	Phosphodiesterase.	0.413
CNGA3	PDE4A	ENSOARP00000014559	ENSOARP00000017441	Cyclic nucleotide-binding domain-containing protein.	Phosphodiesterase.	0.439
CNGA3	PDE6C	ENSOARP00000014559	ENSOARP00000003557	Cyclic nucleotide-binding domain-containing protein.	Phosphodiesterase.	0.937
CNGA3	PDE6H	ENSOARP00000014559	ENSOARP00000022234	Cyclic nucleotide-binding domain-containing protein.	Phosphodiesterase 6H.	0.936
CNGA3	W5NS75_SHEEP	ENSOARP00000014559	ENSOARP00000001015	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.833