STRINGSTRING
ITGAL ITGAL ITGBL1 ITGBL1 ITGA3 ITGA3 ITGA9 ITGA9 COL16A1 COL16A1 ITGA6 ITGA6 ADAM9 ADAM9 FBN1 FBN1 ITGA10 ITGA10 ITGB5 ITGB5 EMILIN1 EMILIN1 ITGA11 ITGA11 MMRN1 MMRN1 VTN VTN ITGB1 ITGB1 ITGAE ITGAE ITGA4 ITGA4 ITGB7 ITGB7 ITGAV ITGAV ITGA5 ITGA5 ADAM17 ADAM17 W5NX55_SHEEP W5NX55_SHEEP ITGB3 ITGB3 ITGA7 ITGA7 ITGB8 ITGB8 EXT1 EXT1 ITGB4 ITGB4 NPNT NPNT CCN3 CCN3 ITGAD ITGAD ITGAX ITGAX ITGAM ITGAM ITGA8 ITGA8 ITGA1 ITGA1 ITGA2 ITGA2 FYB2 FYB2 PLPP3 PLPP3 ITGB6 ITGB6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGALVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1164 aa)
ITGBL1Integrin subunit beta like 1. (392 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1039 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
COL16A1Collagen type XVI alpha 1 chain. (1605 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1069 aa)
ADAM9ADAM metallopeptidase domain 9. (821 aa)
FBN1Fibrillin 1. (2876 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (802 aa)
EMILIN1Elastin microfibril interfacer 1. (990 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1184 aa)
MMRN1Multimerin 1. (1219 aa)
VTNSMB domain-containing protein. (475 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (798 aa)
ITGAEIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (725 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1034 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1051 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1078 aa)
ADAM17ADAM metallopeptidase domain 17. (825 aa)
W5NX55_SHEEPIntegrin_alpha2 domain-containing protein. (100 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (778 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1187 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (743 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (748 aa)
ITGB4Integrin beta. (1835 aa)
NPNTNephronectin. (599 aa)
CCN3Cellular communication network factor 3. (346 aa)
ITGADVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1160 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1161 aa)
ITGAMVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1149 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1064 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1166 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1171 aa)
FYB2FYN binding protein 2. (761 aa)
PLPP3acidPPc domain-containing protein. (312 aa)
ITGB6Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). (787 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.