STRINGSTRING
JAM3 JAM3 W5NX55_SHEEP W5NX55_SHEEP CTNNA3 CTNNA3 W5P3S6_SHEEP W5P3S6_SHEEP DSG2 DSG2 DSC2 DSC2 NINJ1 NINJ1 PARVA PARVA MADCAM1 MADCAM1 ITGAD ITGAD ITGA7 ITGA7 ITGB3 ITGB3 IZUMO1 IZUMO1 ITGB2 ITGB2 ITGAV ITGAV PTPRC PTPRC ITGA5 ITGA5 GLDN GLDN CD2 CD2 CD58 CD58 RNASE10 RNASE10 PKP2 PKP2 CD200 CD200 W5QDC6_SHEEP W5QDC6_SHEEP JUP JUP ITGA4 ITGA4 ITGB7 ITGB7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAM3Junctional adhesion molecule 3. (329 aa)
W5NX55_SHEEPIntegrin_alpha2 domain-containing protein. (100 aa)
CTNNA3Catenin alpha 3. (560 aa)
W5P3S6_SHEEPUncharacterized protein. (157 aa)
DSG2Desmoglein 2. (1125 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (909 aa)
NINJ1Ninjurin 1. (151 aa)
PARVAParvin alpha. (341 aa)
MADCAM1Adhes-Ig_like domain-containing protein. (378 aa)
ITGADVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1160 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1187 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (778 aa)
IZUMO1Izumo-Ig domain-containing protein. (335 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (750 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1051 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1235 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1078 aa)
GLDNGliomedin. (551 aa)
CD2CD2 molecule. (338 aa)
CD58Uncharacterized protein. (248 aa)
RNASE10Inactive ribonuclease-like protein 10; Secreted proximal epididymal protein required for post- testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity (By similarity). (248 aa)
PKP2Plakophilin 2. (829 aa)
CD200CD200 molecule. (299 aa)
W5QDC6_SHEEPIg-like domain-containing protein. (177 aa)
JUPJunction plakoglobin. (747 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1034 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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