34 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZNF112	Uncharacterized protein. (906 aa)
	RAD51AP1	RAD51 associated protein 1. (328 aa)
	BHMG1	Basic helix-loop-helix and HMG-box containing 1. (624 aa)
	CALR	Calreticulin. (417 aa)
	W5NPF4_SHEEP	Uncharacterized protein. (120 aa)
	W5NPG5_SHEEP	Uncharacterized protein. (165 aa)
	W5NQ37_SHEEP	Uncharacterized protein. (489 aa)
	FBXO43	F-box protein 43. (707 aa)
	W5NXV5_SHEEP	KRAB-related domain-containing protein. (294 aa)
	ENSOARP00000003040	annotation not available (294 aa)
	W5P0X3_SHEEP	Uncharacterized protein. (260 aa)
	W5P1C6_SHEEP	Uncharacterized protein. (332 aa)
	FBXO5	F-box protein 5. (413 aa)
	W5P3E2_SHEEP	Uncharacterized protein. (294 aa)
	HORMAD1	HORMA domain containing 1. (393 aa)
	CDC20	Cell division cycle 20. (504 aa)
	MOS	Protein kinase domain-containing protein. (211 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (409 aa)
	W5Q2Z7_SHEEP	Uncharacterized protein. (164 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	WEE2	Wee1-like protein kinase. (566 aa)
	UBE2B	Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	DMRT1	Doublesex and mab-3 related transcription factor 1. (332 aa)
	FZR1	WD_REPEATS_REGION domain-containing protein. (493 aa)
	RAD1	RAD1 checkpoint DNA exonuclease. (279 aa)
	NANOS2	Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa)
	W5PNI9_SHEEP	WD_REPEATS_REGION domain-containing protein. (224 aa)
	OOEP	Oocyte expressed protein isoform 1. (140 aa)
	PIWIL2	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (973 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (391 aa)
	LIF	LIF interleukin 6 family cytokine. (202 aa)
	PSMA8	Proteasome subunit alpha type. (250 aa)
	MSX1	Msh homeobox 1. (284 aa)
	STRA8	Stimulated by retinoic acid 8. (366 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC20	FBXO43	ENSOARP00000022072	ENSOARP00000001648	Cell division cycle 20.	F-box protein 43.	0.554
CDC20	FBXO5	ENSOARP00000022072	ENSOARP00000004240	Cell division cycle 20.	F-box protein 5.	0.989
CDC20	FZR1	ENSOARP00000022072	ENSOARP00000013395	Cell division cycle 20.	WD_REPEATS_REGION domain-containing protein.	0.513
CDC20	TRIP13	ENSOARP00000022072	ENSOARP00000017264	Cell division cycle 20.	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.	0.854
CDC20	W5PNI9_SHEEP	ENSOARP00000022072	ENSOARP00000012015	Cell division cycle 20.	WD_REPEATS_REGION domain-containing protein.	0.511
CDC20	WEE2	ENSOARP00000022072	ENSOARP00000015005	Cell division cycle 20.	Wee1-like protein kinase.	0.413
DMRT1	NANOS2	ENSOARP00000014169	ENSOARP00000012291	Doublesex and mab-3 related transcription factor 1.	Nanos C2HC-type zinc finger 2; Belongs to the nanos family.	0.426
DMRT1	STRA8	ENSOARP00000014169	ENSOARP00000009039	Doublesex and mab-3 related transcription factor 1.	Stimulated by retinoic acid 8.	0.533
ENSOARP00000003040	W5Q2Z7_SHEEP	ENSOARP00000003040	ENSOARP00000017085	annotation not available	Uncharacterized protein.	0.418
FBXO43	CDC20	ENSOARP00000001648	ENSOARP00000022072	F-box protein 43.	Cell division cycle 20.	0.554
FBXO43	FZR1	ENSOARP00000001648	ENSOARP00000013395	F-box protein 43.	WD_REPEATS_REGION domain-containing protein.	0.549
FBXO43	W5PNI9_SHEEP	ENSOARP00000001648	ENSOARP00000012015	F-box protein 43.	WD_REPEATS_REGION domain-containing protein.	0.549
FBXO43	WEE2	ENSOARP00000001648	ENSOARP00000015005	F-box protein 43.	Wee1-like protein kinase.	0.752
FBXO5	CDC20	ENSOARP00000004240	ENSOARP00000022072	F-box protein 5.	Cell division cycle 20.	0.989
FBXO5	FZR1	ENSOARP00000004240	ENSOARP00000013395	F-box protein 5.	WD_REPEATS_REGION domain-containing protein.	0.947
FBXO5	RAD51AP1	ENSOARP00000004240	ENSOARP00000010559	F-box protein 5.	RAD51 associated protein 1.	0.537
FBXO5	W5PNI9_SHEEP	ENSOARP00000004240	ENSOARP00000012015	F-box protein 5.	WD_REPEATS_REGION domain-containing protein.	0.933
FZR1	CDC20	ENSOARP00000013395	ENSOARP00000022072	WD_REPEATS_REGION domain-containing protein.	Cell division cycle 20.	0.513
FZR1	FBXO43	ENSOARP00000013395	ENSOARP00000001648	WD_REPEATS_REGION domain-containing protein.	F-box protein 43.	0.549
FZR1	FBXO5	ENSOARP00000013395	ENSOARP00000004240	WD_REPEATS_REGION domain-containing protein.	F-box protein 5.	0.947