TGF_BETA_2 domain-containing protein.

Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]

TGF_BETA_2 domain-containing protein.

Lin-28 homolog B.

TGF_BETA_2 domain-containing protein.

Signal transducer and activator of transcription.

TGF_BETA_2 domain-containing protein.

Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]

DEAD-box helicase 5; Belongs to the DEAD box helicase family.

DExH-box helicase 9.

DEAD-box helicase 5; Belongs to the DEAD box helicase family.

Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]

DEAD-box helicase 5; Belongs to the DEAD box helicase family.

Fragile X mental retardation 1.

DEAD-box helicase 5; Belongs to the DEAD box helicase family.

FMR1 autosomal homolog 1.

DEAD-box helicase 5; Belongs to the DEAD box helicase family.

Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]

DEAD-box helicase 5; Belongs to the DEAD box helicase family.

TruB pseudouridine synthase family member 1.

DExH-box helicase 9.

DEAD-box helicase 5; Belongs to the DEAD box helicase family.

DExH-box helicase 9.

Receptor protein-tyrosine kinase.

DExH-box helicase 9.

ELAV-like protein; Belongs to the RRM elav family.

DExH-box helicase 9.

mRNA decay activator protein ZFP36; Zinc-finger RNA-binding protein that destabilizes numerous cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as an 3'- untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1, and hence promotes ARE-mediated mRNA deadenylation. Functions also by recruiting compo [...]

DND microRNA-mediated repression inhibitor 1.

FMR1 autosomal homolog 1.

DND microRNA-mediated repression inhibitor 1.

TIA1 cytotoxic granule associated RNA binding protein like 1.

Receptor protein-tyrosine kinase.

DExH-box helicase 9.

Receptor protein-tyrosine kinase.

Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]

Receptor protein-tyrosine kinase.

Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]

Receptor protein-tyrosine kinase.

Signal transducer and activator of transcription.