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| | CCL21 | C-C motif chemokine ligand 21. (131 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa) |
| | CEBPB | BZIP domain-containing protein. (126 aa) |
| | CD274 | CD274 molecule. (293 aa) |
| | PDCD1LG2 | Programmed cell death 1 ligand 2. (302 aa) |
| | TNFAIP8L2 | TNF alpha induced protein 8 like 2. (184 aa) |
| | W5PVR8_SHEEP | Uncharacterized protein. (511 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (471 aa) |
| | ZAP70 | Tyrosine-protein kinase. (616 aa) |
| | IL4I1 | Interleukin 4 induced 1. (501 aa) |
| | RHOA | RHOA. (193 aa) |
| | ZDHHC21 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa) |
| | ZP3 | ZP domain-containing protein. (408 aa) |
| | IL12RB1 | Uncharacterized protein. (731 aa) |
| | GATA3 | GATA binding protein 3. (322 aa) |
| | ARG1 | Arginase. (352 aa) |
| | LGALS1 | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis. (108 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | RARA | Retinoic acid receptor alpha. (453 aa) |
| | ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (256 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (230 aa) |
| | VNN1 | Vanin 1. (501 aa) |
| | ZC3H8 | Zinc finger CCCH-type containing 8. (303 aa) |
| | ADTRP | Androgen dependent TFPI regulating protein. (230 aa) |
| | TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (763 aa) |
| | EFNB1 | Ephrin B1; Belongs to the ephrin family. (348 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (381 aa) |
| | PRKAR1A | Uncharacterized protein. (411 aa) |
| | PAWR | Uncharacterized protein. (168 aa) |
| | IRF1 | Interferon regulatory factor. (322 aa) |
| | FCHO1 | FCH domain only 1. (886 aa) |
| | HSPD1 | Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | W5Q1M3_SHEEP | Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa) |
| | OVAR-DRB1 | Ig-like domain-containing protein. (165 aa) |
| | W5Q266_SHEEP | MHC_II_beta domain-containing protein. (167 aa) |
| | W5Q2C4_SHEEP | Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1235 aa) |
| | SELENOK | Selenoprotein K. (92 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (172 aa) |
| | W5Q2V1_SHEEP | Ig-like domain-containing protein. (266 aa) |
| | EFNB3 | Ephrin B3; Belongs to the ephrin family. (340 aa) |
| | NKAP | NFKB activating protein. (368 aa) |
| | TYK2 | Tyrosine-protein kinase. (1161 aa) |
| | W5Q3B8_SHEEP | Galectin. (123 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | CD6 | CD6 molecule. (656 aa) |
| | W5Q3J8_SHEEP | Ig-like domain-containing protein. (244 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (405 aa) |
| | CD5 | CD5 molecule. (495 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1134 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | LOC101102156 | Galectin. (355 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | GLMN | Glomulin, FKBP associated protein. (592 aa) |
| | DQA | MHC class II DQA; Belongs to the MHC class II family. (255 aa) |
| | SCRIB | Scribble planar cell polarity protein. (1499 aa) |
| | W5Q4M2_SHEEP | Uncharacterized protein. (193 aa) |
| | W5Q4S5_SHEEP | Ig-like domain-containing protein. (265 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (296 aa) |
| | EPHB6 | EPH receptor B6. (931 aa) |
| | BTNL2 | Butyrophilin like 2. (593 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1052 aa) |
| | ARG2 | Arginase. (354 aa) |
| | BMP4 | TGF_BETA_2 domain-containing protein. (409 aa) |
| | LCK | Tyrosine-protein kinase. (559 aa) |
| | NCK2 | NCK adaptor protein 2. (343 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | IL36B | Interleukin-1. (154 aa) |
| | W5QHY0_SHEEP | Uncharacterized protein. (416 aa) |
| | BCL6 | BCL6 transcription repressor. (702 aa) |
| | W5QH04_SHEEP | Amine oxidase. (518 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (248 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa) |
| | TFRC | Transferrin receptor. (770 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (285 aa) |
| | CD86 | Ig-like domain-containing protein. (338 aa) |
| | W5QFT0_SHEEP | Uncharacterized protein. (175 aa) |
| | W5QFS8_SHEEP | Uncharacterized protein. (159 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (797 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (419 aa) |
| | FUT9 | Fucosyltransferase 9. (361 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (809 aa) |
| | W5QF49_SHEEP | Ig-like domain-containing protein. (229 aa) |
| | IHH | Indian hedgehog signaling molecule. (378 aa) |
| | CD80 | Uncharacterized protein. (309 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (433 aa) |
| | TIGIT | T cell immunoreceptor with Ig and ITIM domains. (297 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (470 aa) |
| | IGFBP2 | Insulin-like growth factor-binding protein 2; Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. (231 aa) |
| | SOX12 | Uncharacterized protein. (117 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (542 aa) |
| | W5QCM7_SHEEP | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (528 aa) |
| | W5QCK3_SHEEP | Ig-like domain-containing protein. (99 aa) |
| | STAT5B | Signal transducer and activator of transcription. (791 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (90 aa) |
| | HHLA2 | HERV-H LTR-associating 2. (334 aa) |
| | CD44 | CD44 molecule (Indian blood group). (705 aa) |
| | CBLB | Cbl proto-oncogene B. (983 aa) |
| | TNFRSF13C | TNF receptor superfamily member 13C. (187 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (390 aa) |
| | FGL2 | Fibrinogen like 2. (441 aa) |
| | NFKBIZ | NFKB inhibitor zeta. (624 aa) |
| | W5QAT4_SHEEP | Uncharacterized protein. (290 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (210 aa) |
| | ICOS | Inducible T cell costimulator. (209 aa) |
| | CTLA4 | Cytotoxic T-lymphocyte-associated protein 4. (221 aa) |
| | CD28 | IGv domain-containing protein. (265 aa) |
| | W5Q9P4_SHEEP | BZIP domain-containing protein. (372 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (153 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (543 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (620 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1013 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) |
| | GLI3 | GLI family zinc finger 3. (1213 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (713 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (223 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (865 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (335 aa) |
| | LOC443162 | Galectin. (162 aa) |
| | W5NT44_SHEEP | AIG1-type G domain-containing protein. (311 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | BMI1 | RING-type domain-containing protein. (326 aa) |
| | W5NU18_SHEEP | AIG1-type G domain-containing protein. (344 aa) |
| | W5NU82_SHEEP | AIG1-type G domain-containing protein. (307 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (222 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (393 aa) |
| | W5NV38_SHEEP | Uncharacterized protein. (88 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | W5NV67_SHEEP | Uncharacterized protein. (87 aa) |
| | W5NVJ1_SHEEP | HMG box domain-containing protein. (612 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (747 aa) |
| | W5NVV4_SHEEP | Ig-like domain-containing protein. (163 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (221 aa) |
| | IDO1 | Indoleamine-pyrrole 2,3 dioxygenase. (410 aa) |
| | W5NWG2_SHEEP | Uncharacterized protein. (42 aa) |
| | TMEM131L | Transmembrane 131 like. (1559 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (204 aa) |
| | MAD1L1 | Uncharacterized protein. (208 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (292 aa) |
| | CBFB | Core-binding factor subunit beta. (143 aa) |
| | W5NXG9_SHEEP | TNF_2 domain-containing protein. (153 aa) |
| | W5NXL0_SHEEP | Ig-like domain-containing protein. (224 aa) |
| | W5NXN9_SHEEP | AIG1-type G domain-containing protein. (204 aa) |
| | SOX13 | Uncharacterized protein. (176 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (630 aa) |
| | XBP1 | BZIP domain-containing protein. (412 aa) |
| | W5NYC7_SHEEP | Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa) |
| | W5NYD7_SHEEP | Uncharacterized protein. (99 aa) |
| | TARM1 | Uncharacterized protein. (292 aa) |
| | RASAL3 | RAS protein activator like 3. (1018 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | CCL25 | SCY domain-containing protein. (150 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (553 aa) |
| | TSPAN32 | Uncharacterized protein. (227 aa) |
| | IGF2 | Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...] (263 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1238 aa) |
| | SMAD7 | MH2 domain-containing protein. (257 aa) |
| | ZP4 | Zona pellucida glycoprotein 4. (540 aa) |
| | ADA | Adenosine deaminase. (363 aa) |
| | W5P2C3_SHEEP | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (363 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1153 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (473 aa) |
| | W5P404_SHEEP | Uncharacterized protein. (393 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (905 aa) |
| | VSIG4 | V-set and immunoglobulin domain containing 4. (392 aa) |
| | W5P5N5_SHEEP | Uncharacterized protein. (163 aa) |
| | RIPOR2 | PL48 domain-containing protein. (1092 aa) |
| | W5P650_SHEEP | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (253 aa) |
| | MALT1 | MALT1 paracaspase. (764 aa) |
| | TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (288 aa) |
| | CHST2 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (437 aa) |
| | LGALS7 | Galectin. (139 aa) |
| | LOC101112249 | Galectin. (139 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (652 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (166 aa) |
| | BAD | BCL2 associated agonist of cell death. (179 aa) |
| | W5P8I1_SHEEP | Uncharacterized protein. (145 aa) |
| | DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (765 aa) |
| | LAG3 | Lymphocyte activating 3. (520 aa) |
| | W5NS64_SHEEP | C-type lectin domain-containing protein. (167 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (655 aa) |
| | STAT5A | Signal transducer and activator of transcription 5A; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. (788 aa) |
| | W5NRI4_SHEEP | Uncharacterized protein. (59 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (700 aa) |
| | RHOH | RhoH. (191 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (409 aa) |
| | W5NPE8_SHEEP | Ig-like domain-containing protein. (77 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (161 aa) |
| | VSIR | V-set immunoregulatory receptor. (311 aa) |
| | SHH | Uncharacterized protein. (232 aa) |
| | LRRC1 | Leucine rich repeat containing 1. (443 aa) |
| | SKAP1 | Src kinase associated phosphoprotein 1. (270 aa) |
| | MARCHF7 | Membrane associated ring-CH-type finger 7. (706 aa) |
| | LOC101108961 | Ig-like domain-containing protein. (262 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | CCDC88B | Coiled-coil domain containing 88B. (1375 aa) |
| | DYA | Ig-like domain-containing protein; Belongs to the MHC class II family. (318 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (249 aa) |
| | LOC101115073 | Ig-like domain-containing protein. (267 aa) |
| | ABL1 | Tyrosine-protein kinase. (1020 aa) |
| | SIRPA | Uncharacterized protein. (506 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (273 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (275 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2408 aa) |
| | IL6ST | Interleukin 6 signal transducer. (918 aa) |
| | W5PCJ1_SHEEP | Uncharacterized protein. (301 aa) |
| | W5PCM7_SHEEP | Uncharacterized protein. (388 aa) |
| | ASS1 | Argininosuccinate synthase 1. (410 aa) |
| | IL20RB | Interleukin 20 receptor subunit beta. (310 aa) |
| | FAM49B | Family with sequence similarity 49 member B. (373 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | W5PD66_SHEEP | AGC-kinase C-terminal domain-containing protein. (403 aa) |
| | SYK | Tyrosine-protein kinase. (633 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation; Belongs to the IL-7/IL-9 family. (142 aa) |
| | LOC101109746 | Ig-like domain-containing protein. (267 aa) |
| | AIF1 | Allograft inflammatory factor 1. (147 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) |
| | CD27 | CD27 molecule. (274 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | TBX21 | T-box transcription factor 21. (533 aa) |
| | GCNT1 | Glucosaminyl (N-acetyl) transferase 1. (428 aa) |
| | CCL28 | C-C motif chemokine. (129 aa) |
| | PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (442 aa) |
| | SLAMF1 | Ig-like domain-containing protein. (378 aa) |
| | PYCARD | PYD and CARD domain containing. (196 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (201 aa) |
| | LAX1 | Lymphocyte transmembrane adaptor 1. (378 aa) |
| | FGL1 | Fibrinogen like 1. (315 aa) |
| | CCL19 | C-C motif chemokine. (115 aa) |
| | IL23A | Uncharacterized protein. (190 aa) |
| | PLA2G2F | Phospholipase A(2). (196 aa) |
| | PLA2G2D | Phospholipase A(2). (147 aa) |
| | DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1817 aa) |
| | ZMIZ1-2 | Zmiz1_N domain-containing protein. (68 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (845 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (969 aa) |
| | FUT4 | Fucosyltransferase 4. (364 aa) |
| | EGR3 | Early growth response 3. (351 aa) |
| | TMIGD2 | Transmembrane and immunoglobulin domain containing 2. (307 aa) |
| | FOXP3 | Fork-head domain-containing protein. (474 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | SELP | P-selectin; Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. (769 aa) |
| | FOXO3 | Fork-head domain-containing protein. (473 aa) |
| | PRDX2 | Peroxiredoxin 2. (198 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (602 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase, mitochondrial. (893 aa) |
| | HAS2 | Hyaluronan synthase 2. (558 aa) |
| | SELE | Uncharacterized protein. (484 aa) |
| | IL12RB2 | Uncharacterized protein. (867 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | W5PNY3_SHEEP | SH2 domain-containing protein. (459 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa) |
| | TNFRSF21 | TNF receptor superfamily member 21. (618 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1251 aa) |
| | ILDR2 | Immunoglobulin like domain containing receptor 2. (531 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa) |
| | SLC7A1 | AA_permease_C domain-containing protein. (319 aa) |
| | DHPS | Uncharacterized protein. (369 aa) |
| | IL15 | Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. (161 aa) |
| | W5PRK3_SHEEP | Cyclic nucleotide-binding domain-containing protein. (213 aa) |
| | WNK1 | WNK lysine deficient protein kinase 1. (2337 aa) |
| | ITGB2 | Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (750 aa) |
| | W5PSW0_SHEEP | Ig-like domain-containing protein. (295 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | GPNMB | Glycoprotein nmb. (555 aa) |
| | LOXL3 | Lysyl oxidase like 3. (737 aa) |
| | ST3GAL4 | Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (334 aa) |
| | W5PTP1_SHEEP | Amino_oxidase domain-containing protein. (265 aa) |
| | CD83 | CD83 molecule. (205 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (663 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1140 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (442 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (619 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (324 aa) |
| | DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2101 aa) |
| | HLX | Homeobox domain-containing protein. (241 aa) |
