node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTNNB1 | EP300 | ENSOARP00000003072 | ENSOARP00000019268 | Catenin beta 1. | E1A binding protein p300. | 0.992 |
CTNNB1 | IFNG | ENSOARP00000003072 | ENSOARP00000002060 | Catenin beta 1. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.483 |
CTNNB1 | IGF1 | ENSOARP00000003072 | ENSOARP00000017024 | Catenin beta 1. | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] | 0.538 |
CTNNB1 | PAX6 | ENSOARP00000003072 | ENSOARP00000017386 | Catenin beta 1. | Paired box 6. | 0.578 |
CTNNB1 | TGFB1 | ENSOARP00000003072 | ENSOARP00000008013 | Catenin beta 1. | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.693 |
EP300 | CTNNB1 | ENSOARP00000019268 | ENSOARP00000003072 | E1A binding protein p300. | Catenin beta 1. | 0.992 |
EP300 | GATA3 | ENSOARP00000019268 | ENSOARP00000014958 | E1A binding protein p300. | GATA binding protein 3. | 0.937 |
EP300 | GTF2B | ENSOARP00000019268 | ENSOARP00000016063 | E1A binding protein p300. | General transcription factor IIB. | 0.590 |
EP300 | PAX6 | ENSOARP00000019268 | ENSOARP00000017386 | E1A binding protein p300. | Paired box 6. | 0.491 |
EP300 | RB1 | ENSOARP00000019268 | ENSOARP00000008850 | E1A binding protein p300. | RB transcriptional corepressor 1. | 0.405 |
EP300 | TGFB1 | ENSOARP00000019268 | ENSOARP00000008013 | E1A binding protein p300. | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.506 |
GATA3 | EP300 | ENSOARP00000014958 | ENSOARP00000019268 | GATA binding protein 3. | E1A binding protein p300. | 0.937 |
GATA3 | HAND2 | ENSOARP00000014958 | ENSOARP00000016468 | GATA binding protein 3. | Heart and neural crest derivatives expressed 2. | 0.623 |
GATA3 | IFNG | ENSOARP00000014958 | ENSOARP00000002060 | GATA binding protein 3. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.847 |
GATA3 | TGFB1 | ENSOARP00000014958 | ENSOARP00000008013 | GATA binding protein 3. | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.403 |
GTF2B | EP300 | ENSOARP00000016063 | ENSOARP00000019268 | General transcription factor IIB. | E1A binding protein p300. | 0.590 |
HAND2 | GATA3 | ENSOARP00000016468 | ENSOARP00000014958 | Heart and neural crest derivatives expressed 2. | GATA binding protein 3. | 0.623 |
IFNG | CTNNB1 | ENSOARP00000002060 | ENSOARP00000003072 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Catenin beta 1. | 0.483 |
IFNG | GATA3 | ENSOARP00000002060 | ENSOARP00000014958 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | GATA binding protein 3. | 0.847 |
IFNG | IGF1 | ENSOARP00000002060 | ENSOARP00000017024 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] | 0.576 |