STRINGSTRING
RAD21 RAD21 CORT CORT C14orf39 C14orf39 FAM43A FAM43A SYCP1 SYCP1 SYCE3 SYCE3 W5QF56_SHEEP W5QF56_SHEEP CCNB1IP1 CCNB1IP1 MEAF6 MEAF6 SMC1B SMC1B RNF212B RNF212B REC8 REC8 HJURP HJURP REC114 REC114 CENPA CENPA RAD21L1 RAD21L1 SNPH SNPH FAM43B FAM43B CENPO CENPO SPO11 SPO11 SPC24 SPC24 KAT5 KAT5 MTBP MTBP RRS1 RRS1 PLK1 PLK1 STAG3 STAG3 RAD9B RAD9B W5Q6B9_SHEEP W5Q6B9_SHEEP ENSOARP00000018020 ENSOARP00000018020 SMC6 SMC6 TEX12 TEX12 DSN1 DSN1 SGO2 SGO2 ENSOARP00000017131 ENSOARP00000017131 TEX11 TEX11 SGO1 SGO1 FBXO28 FBXO28 SYCP2 SYCP2 SYCP3 SYCP3 W5Q0W9_SHEEP W5Q0W9_SHEEP SYCP2L SYCP2L ENSOARP00000016348 ENSOARP00000016348 W5PYU1_SHEEP W5PYU1_SHEEP SS18L1 SS18L1 W5PYF0_SHEEP W5PYF0_SHEEP BUB1 BUB1 W5PXP9_SHEEP W5PXP9_SHEEP NCAPH NCAPH STAG2 STAG2 SKA3 SKA3 CDT1 CDT1 LOC101117679 LOC101117679 NIFK NIFK NCAPD3 NCAPD3 ZWINT ZWINT BLM BLM FKBP6 FKBP6 MSH4 MSH4 RAD52 RAD52 DYNLL1 DYNLL1 HUS1 HUS1 W5PS09_SHEEP W5PS09_SHEEP CENPQ CENPQ SKA2 SKA2 CHEK1 CHEK1 RAD1 RAD1 RAD9A RAD9A W5PMZ0_SHEEP W5PMZ0_SHEEP W5P234_SHEEP W5P234_SHEEP CKAP5 CKAP5 MIS12 MIS12 SKA1 SKA1 TRAPPC12 TRAPPC12 BIRC5 BIRC5 AFMID AFMID LOC101102276 LOC101102276 CENPH CENPH SHOC1 SHOC1 MEI4 MEI4 CENPC CENPC W5PB19_SHEEP W5PB19_SHEEP ANAPC16 ANAPC16 TTK TTK W5PBQ6_SHEEP W5PBQ6_SHEEP SMC2 SMC2 CENPW CENPW STAG1 STAG1 NCAPG2 NCAPG2 NCAPD2 NCAPD2 CENPN CENPN NSMCE2 NSMCE2 BOD1L1 BOD1L1 SMC1A SMC1A NDE1 NDE1 BOD1 BOD1 CHAMP1 CHAMP1 W5PIJ1_SHEEP W5PIJ1_SHEEP ITGB3BP ITGB3BP SMC3 SMC3 GPATCH11 GPATCH11 W5PJN9_SHEEP W5PJN9_SHEEP W5P1T8_SHEEP W5P1T8_SHEEP SPC25 SPC25 NCAPG NCAPG ZIM3 ZIM3 CENPT CENPT RCC1 RCC1 W5NXW0_SHEEP W5NXW0_SHEEP SMC4 SMC4 MLH3 MLH3 RSKR RSKR CENPI CENPI BANF1 BANF1 RSPH10B RSPH10B SPAG5 SPAG5 CDCA7 CDCA7 WAPL WAPL HMGB4 HMGB4 CDYL CDYL HMGB2 HMGB2 SYCE2 SYCE2 W5PKF7_SHEEP W5PKF7_SHEEP NSL1 NSL1 W5PL10_SHEEP W5PL10_SHEEP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD21RAD21 cohesin complex component. (630 aa)
CORTSomatostatin domain-containing protein. (105 aa)
C14orf39Chromosome 14 open reading frame 39. (584 aa)
FAM43AFamily with sequence similarity 43 member A. (421 aa)
SYCP1Synaptonemal complex protein 1. (1000 aa)
SYCE3Synaptonemal complex central element protein 3. (87 aa)
W5QF56_SHEEPUncharacterized protein. (600 aa)
CCNB1IP1Cyclin B1 interacting protein 1. (277 aa)
MEAF6MYST/Esa1 associated factor 6. (184 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
RNF212BRing finger protein 212B. (300 aa)
REC8REC8 meiotic recombination protein. (592 aa)
HJURPHolliday junction recognition protein. (699 aa)
REC114REC114 meiotic recombination protein. (214 aa)
CENPAHistone domain-containing protein. (139 aa)
RAD21L1RAD21 cohesin complex component like 1. (554 aa)
SNPHSyntaphilin. (545 aa)
FAM43BFamily with sequence similarity 43 member B. (176 aa)
CENPOUncharacterized protein. (296 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (395 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (221 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (543 aa)
MTBPMDM2 binding protein. (926 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (358 aa)
PLK1Serine/threonine-protein kinase PLK. (605 aa)
STAG3Stromal antigen 3. (1275 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (429 aa)
W5Q6B9_SHEEPGFA domain-containing protein. (217 aa)
ENSOARP00000018020annotation not available (91 aa)
SMC6Structural maintenance of chromosomes 6. (1101 aa)
TEX12Testis expressed 12. (123 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (412 aa)
SGO2Shugoshin 2. (1245 aa)
ENSOARP00000017131annotation not available (209 aa)
TEX11Testis expressed 11. (920 aa)
SGO1Shugoshin_C domain-containing protein. (521 aa)
FBXO28F-box protein 28. (371 aa)
SYCP2Synaptonemal complex protein 2. (1260 aa)
SYCP3Synaptonemal complex protein 3. (225 aa)
W5Q0W9_SHEEPDynein light chain. (88 aa)
SYCP2LSynaptonemal complex protein 2 like. (856 aa)
ENSOARP00000016348annotation not available (209 aa)
W5PYU1_SHEEPFHA domain-containing protein. (3257 aa)
SS18L1SS18L1 subunit of BAF chromatin remodeling complex. (396 aa)
W5PYF0_SHEEPShugoshin_C domain-containing protein. (378 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1081 aa)
W5PXP9_SHEEPHSF_DOMAIN domain-containing protein. (431 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (732 aa)
STAG2Stromal antigen 2. (1233 aa)
SKA3Spindle and kinetochore associated complex subunit 3. (417 aa)
CDT1Chromatin licensing and DNA replication factor 1. (490 aa)
LOC101117679Uncharacterized protein. (206 aa)
NIFKNucleolar protein interacting with the FHA domain of MKI67. (296 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1398 aa)
ZWINTZW10 interacting kinetochore protein. (286 aa)
BLMBLM RecQ like helicase. (1429 aa)
FKBP6Peptidylprolyl isomerase. (331 aa)
MSH4MutS homolog 4. (935 aa)
RAD52RAD52 homolog, DNA repair protein. (416 aa)
DYNLL1Dynein light chain. (91 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (288 aa)
W5PS09_SHEEPHistone domain-containing protein. (142 aa)
CENPQCentromere protein Q. (271 aa)
SKA2Spindle and kinetochore associated complex subunit 2. (120 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
RAD1RAD1 checkpoint DNA exonuclease. (279 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (393 aa)
W5PMZ0_SHEEPUncharacterized protein. (1538 aa)
W5P234_SHEEPUncharacterized protein. (106 aa)
CKAP5Cytoskeleton associated protein 5. (2075 aa)
MIS12Uncharacterized protein. (206 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
TRAPPC12Trafficking protein particle complex 12. (634 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (307 aa)
LOC101102276Uncharacterized protein. (201 aa)
CENPHCentromere protein H. (244 aa)
SHOC1Shortage in chiasmata 1. (1511 aa)
MEI4Meiotic double-stranded break formation protein 4. (395 aa)
CENPCCentromere protein C; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions; Belongs to the CENP-C/MIF2 family. (944 aa)
W5PB19_SHEEPUncharacterized protein. (553 aa)
ANAPC16Anaphase promoting complex subunit 16. (110 aa)
TTKTTK protein kinase. (856 aa)
W5PBQ6_SHEEPUncharacterized protein. (171 aa)
SMC2Structural maintenance of chromosomes protein. (1191 aa)
CENPWCentromere protein W. (103 aa)
STAG1Stromal antigen 1. (1258 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1140 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1394 aa)
CENPNCentromere protein N. (339 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (277 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (2919 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
NDE1NudE neurodevelopment protein 1. (350 aa)
BOD1Uncharacterized protein. (159 aa)
CHAMP1Chromosome alignment maintaining phosphoprotein 1. (781 aa)
W5PIJ1_SHEEPVert_HS_TF domain-containing protein. (447 aa)
ITGB3BPUncharacterized protein. (212 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
GPATCH11G-patch domain containing 11. (262 aa)
W5PJN9_SHEEPUncharacterized protein. (296 aa)
W5P1T8_SHEEPHistone domain-containing protein. (155 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (226 aa)
NCAPGNon-SMC condensin I complex subunit G. (1030 aa)
ZIM3KRAB domain-containing protein. (174 aa)
CENPTCentromere protein T. (566 aa)
RCC1Regulator of chromosome condensation 1. (422 aa)
W5NXW0_SHEEPHistone domain-containing protein. (113 aa)
SMC4Structural maintenance of chromosomes protein. (1288 aa)
MLH3MutL homolog 3. (1485 aa)
RSKRRibosomal protein S6 kinase related. (278 aa)
CENPICentromere protein I. (740 aa)
BANF1Barrier to autointegration factor 1. (89 aa)
RSPH10BUncharacterized protein. (872 aa)
SPAG5Sperm associated antigen 5. (1194 aa)
CDCA7Cell division cycle associated 7. (452 aa)
WAPLWAPL cohesin release factor. (1237 aa)
HMGB4High mobility group box 4. (194 aa)
CDYLChromodomain Y like. (546 aa)
HMGB2Uncharacterized protein. (209 aa)
SYCE2Synaptonemal complex central element protein 2. (184 aa)
W5PKF7_SHEEPDynein light chain. (91 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (283 aa)
W5PL10_SHEEPUncharacterized protein. (376 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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