12 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5NVS0_SHEEP	ADH_N domain-containing protein. (126 aa)
	W5NUH5_SHEEP	Uncharacterized protein. (281 aa)
	MECR	Mitochondrial trans-2-enoyl-CoA reductase. (373 aa)
	ZADH2	Zinc binding alcohol dehydrogenase domain containing 2. (365 aa)
	VAT1L	Vesicle amine transport 1 like. (359 aa)
	RTN4IP1	Reticulon 4 interacting protein 1. (396 aa)
	CRYZ	Crystallin zeta. (330 aa)
	LOC101111965	PKS_ER domain-containing protein. (378 aa)
	W5Q247_SHEEP	PKS_ER domain-containing protein. (375 aa)
	W5Q2E8_SHEEP	PKS_ER domain-containing protein. (354 aa)
	ADH5	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
	SORD	Sorbitol dehydrogenase; Polyol dehydrogenase that catalyzes the reversible NAD(+)- dependent oxidation of various sugar alcohols. Is mostly active with xylitol, L-iditol and D-sorbitol (D-glucitol) as substrates, leading to the C2-oxidized products D-xylulose, L-sorbose and D-fructose, respectively. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism (By similarity). May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility (By simil [...] (358 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101111965	W5NVS0_SHEEP	ENSOARP00000016513	ENSOARP00000002266	PKS_ER domain-containing protein.	ADH_N domain-containing protein.	0.711
MECR	RTN4IP1	ENSOARP00000002487	ENSOARP00000011932	Mitochondrial trans-2-enoyl-CoA reductase.	Reticulon 4 interacting protein 1.	0.490
MECR	ZADH2	ENSOARP00000002487	ENSOARP00000004882	Mitochondrial trans-2-enoyl-CoA reductase.	Zinc binding alcohol dehydrogenase domain containing 2.	0.561
RTN4IP1	MECR	ENSOARP00000011932	ENSOARP00000002487	Reticulon 4 interacting protein 1.	Mitochondrial trans-2-enoyl-CoA reductase.	0.490
W5NVS0_SHEEP	LOC101111965	ENSOARP00000002266	ENSOARP00000016513	ADH_N domain-containing protein.	PKS_ER domain-containing protein.	0.711
ZADH2	MECR	ENSOARP00000004882	ENSOARP00000002487	Zinc binding alcohol dehydrogenase domain containing 2.	Mitochondrial trans-2-enoyl-CoA reductase.	0.561