16 items (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCN4	Cyclic nucleotide-binding domain-containing protein. (774 aa)
	CNGA2	Cyclic nucleotide gated channel subunit alpha 2. (663 aa)
	HCN2	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (885 aa)
	CNGB3	Cyclic nucleotide-binding domain-containing protein. (665 aa)
	CNGA3	Cyclic nucleotide-binding domain-containing protein. (700 aa)
	PRKG1	Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (471 aa)
	PRKAR1A	Uncharacterized protein. (411 aa)
	PRKG2	cGMP-dependent protein kinase. (762 aa)
	HCN1	Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (548 aa)
	CNGA4	Cyclic nucleotide gated channel subunit alpha 4. (570 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (305 aa)
	CNBD2	Cyclic nucleotide binding domain containing 2. (583 aa)
	CNGA1	Cyclic nucleotide gated channel subunit alpha 1. (690 aa)
	W5NS75_SHEEP	Cyclic nucleotide-binding domain-containing protein. (1315 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (377 aa)

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNGA1	CNGB3	ENSOARP00000017942	ENSOARP00000012474	Cyclic nucleotide gated channel subunit alpha 1.	Cyclic nucleotide-binding domain-containing protein.	0.925
CNGA1	W5NS75_SHEEP	ENSOARP00000017942	ENSOARP00000001015	Cyclic nucleotide gated channel subunit alpha 1.	Cyclic nucleotide-binding domain-containing protein.	0.999
CNGA2	CNGA3	ENSOARP00000009206	ENSOARP00000014559	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide-binding domain-containing protein.	0.547
CNGA2	CNGA4	ENSOARP00000009206	ENSOARP00000020182	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide gated channel subunit alpha 4.	0.994
CNGA2	CNGB3	ENSOARP00000009206	ENSOARP00000012474	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide-binding domain-containing protein.	0.851
CNGA2	W5NS75_SHEEP	ENSOARP00000009206	ENSOARP00000001015	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide-binding domain-containing protein.	0.977
CNGA3	CNGA2	ENSOARP00000014559	ENSOARP00000009206	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide gated channel subunit alpha 2.	0.547
CNGA3	CNGB3	ENSOARP00000014559	ENSOARP00000012474	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.947
CNGA3	W5NS75_SHEEP	ENSOARP00000014559	ENSOARP00000001015	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.833
CNGA4	CNGA2	ENSOARP00000020182	ENSOARP00000009206	Cyclic nucleotide gated channel subunit alpha 4.	Cyclic nucleotide gated channel subunit alpha 2.	0.994
CNGA4	CNGB3	ENSOARP00000020182	ENSOARP00000012474	Cyclic nucleotide gated channel subunit alpha 4.	Cyclic nucleotide-binding domain-containing protein.	0.867
CNGA4	W5NS75_SHEEP	ENSOARP00000020182	ENSOARP00000001015	Cyclic nucleotide gated channel subunit alpha 4.	Cyclic nucleotide-binding domain-containing protein.	0.978
CNGB3	CNGA1	ENSOARP00000012474	ENSOARP00000017942	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide gated channel subunit alpha 1.	0.925
CNGB3	CNGA2	ENSOARP00000012474	ENSOARP00000009206	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide gated channel subunit alpha 2.	0.851
CNGB3	CNGA3	ENSOARP00000012474	ENSOARP00000014559	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide-binding domain-containing protein.	0.947
CNGB3	CNGA4	ENSOARP00000012474	ENSOARP00000020182	Cyclic nucleotide-binding domain-containing protein.	Cyclic nucleotide gated channel subunit alpha 4.	0.867
HCN1	HCN2	ENSOARP00000009123	ENSOARP00000009444	Hyperpolarization activated cyclic nucleotide gated potassium channel 1.	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.	0.901
HCN2	HCN1	ENSOARP00000009444	ENSOARP00000009123	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.	Hyperpolarization activated cyclic nucleotide gated potassium channel 1.	0.901
HCN2	HCN4	ENSOARP00000009444	ENSOARP00000020411	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.	Cyclic nucleotide-binding domain-containing protein.	0.902
HCN4	HCN2	ENSOARP00000020411	ENSOARP00000009444	Cyclic nucleotide-binding domain-containing protein.	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.	0.902